Skin science article
Shiseido Benefiance Wrinkle Smoothing Contour Serum Versus NeoStrata Skin Active Triple Therapy Lifting Serum
Shiseido Benefiance Wrinkle Smoothing Contour Serum Versus NeoStrata Skin Active Triple Therapy Lifting Serum This anti-aging serum is formulated around Retinyl Acetate and Caffeine to soften the look of wrinkles. This anti-aging serum is formulated around Glu
Shiseido Benefiance Wrinkle Smoothing Contour Serum Versus NeoStrata Skin Active Triple Therapy Lifting Serum
This anti-aging serum is formulated around Retinyl Acetate and Caffeine to soften the look of wrinkles.
This anti-aging serum is formulated around Gluconolactone to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
Pentaerythrityl Tetraethylhexanoate
Dimethicone
Glycerin
Dipropylene Glycol
Sd Alcohol 40-B
Behenyl Alcohol
Silica
PEG-400
Batyl Alcohol
Phenoxyethanol
Methylparaben
Carbomer
Dimethylacrylamide/Sodium Acryloyldimethyltaurate Crosspolymer
Trisodium EDTA
Tocopheryl Acetate
Retinyl Acetate
Alcohol
Helianthus Annuus Seed Oil
BHT
Polyquaternium-51
Parfum
Potassium Hydroxide
Caffeine
Xanthan Gum
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
PPG-3 Dipivalate
Rosa Canina Fruit Oil
CI 77492
Tocopherol
Sapindus Mukorossi Peel Extract
Linalool
Limonene
Sodium Metabisulfite
Triisostearin
Uncaria Gambir Extract
Citronellol
Angelica Keiskei Leaf/Stem Extract
Trimethylolpropane Triethylhexanoate
Geraniol
Cellulose
Camellia Sinensis Leaf Extract
Sodium Acetylated Hyaluronate
Hydroxyproline
Ziziphus Jujuba Fruit Extract
Chlorella Vulgaris Extract
Methicone
Tetradecene
Eucheuma Serra/Grateloupia Sparsa/Saccharina Angustata/Ulva Linza/Undaria Pinnatifida Extract
Curcuma Longa Rhizome Extract
Saccharina Angustata/Undaria Pinnatifida Extract
Panax Ginseng Root Extract
Ascorbyl Dipalmitate
Water, Butylene Glycol, Pentaerythrityl Tetraethylhexanoate, Dimethicone, Glycerin, Dipropylene Glycol, Sd Alcohol 40-B, Behenyl Alcohol, Silica, PEG-400, Batyl Alcohol, Phenoxyethanol, Methylparaben, Carbomer, Dimethylacrylamide/Sodium Acryloyldimethyltaurate Crosspolymer, Trisodium EDTA, Tocopheryl Acetate, Retinyl Acetate, Alcohol, Helianthus Annuus Seed Oil, BHT, Polyquaternium-51, Parfum, Potassium Hydroxide, Caffeine, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, PPG-3 Dipivalate, Rosa Canina Fruit Oil, CI 77492, Tocopherol, Sapindus Mukorossi Peel Extract, Linalool, Limonene, Sodium Metabisulfite, Triisostearin, Uncaria Gambir Extract, Citronellol, Angelica Keiskei Leaf/Stem Extract, Trimethylolpropane Triethylhexanoate, Geraniol, Cellulose, Camellia Sinensis Leaf Extract, Sodium Acetylated Hyaluronate, Hydroxyproline, Ziziphus Jujuba Fruit Extract, Chlorella Vulgaris Extract, Methicone, Tetradecene, Eucheuma Serra/Grateloupia Sparsa/Saccharina Angustata/Ulva Linza/Undaria Pinnatifida Extract, Curcuma Longa Rhizome Extract, Saccharina Angustata/Undaria Pinnatifida Extract, Panax Ginseng Root Extract, Ascorbyl Dipalmitate
PEG-8
Gluconolactone
1,2-Hexanediol
Cyclopentasiloxane
Pentylene Glycol
PEG-12 Dimethicone
Polymethylsilsesquioxane
Acetyl Tyrosinamide
Cyclohexasiloxane
Hydrolyzed Sodium Hyaluronate
Dimethiconol
Biosaccharide Gum-1
Polyacrylate-13
Polyisobutene
Isopropyl Myristate
Polysorbate 20
Sodium Sulfite
Ammonium Hydroxide
Caprylyl Glycol
Methyldihydrojasmonate
2,6-Dimethyl-7-Octen-2-Ol
Ethyl Acetoacetate
Methyl Benzodioxepinone
Chlorphenesin
CI 17200
CI 42090
Water, PEG-8, Gluconolactone, 1,2-Hexanediol, Cyclopentasiloxane, Glycerin, Pentylene Glycol, PEG-12 Dimethicone, Polymethylsilsesquioxane, Acetyl Tyrosinamide, Cyclohexasiloxane, Hydrolyzed Sodium Hyaluronate, Dimethiconol, Biosaccharide Gum-1, Polyacrylate-13, Polyisobutene, Isopropyl Myristate, Polysorbate 20, Sodium Sulfite, BHT, Ammonium Hydroxide, Caprylyl Glycol, Xanthan Gum, Methyldihydrojasmonate, 2,6-Dimethyl-7-Octen-2-Ol, Ethyl Acetoacetate, Methyl Benzodioxepinone, Phenoxyethanol, Chlorphenesin, CI 17200, CI 42090
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
BHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.