Shiseido Ultimune Power Infusing Serum Concentrate Versus Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide

Shiseido Ultimune Power Infusing Serum Concentrate Versus Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide

This barrier-repair serum is formulated around Trehalose to strengthen the skin barrier and soften the look of wrinkles.

This anti-aging serum is formulated around Niacinamide and Ceramide NP to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Alcohol Denat.

Glycerin

Butylene Glycol

PEG/PPG-17/4 Dimethyl Ether

Triethylhexanoin

Cyclohexasiloxane

Dimethicone

Phenoxyethanol

Trehalose

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

PEG-14m

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tocopheryl Acetate

PEG/PPG-14/7 Dimethyl Ether

Rosa Damascena Flower Water

Parfum

Disodium EDTA

Potassium Hydroxide

Silica

Isoceteth-10

Linalool

Lauryl Betaine

Ginkgo Biloba Leaf Extract

Geraniol

Citronellol

Origanum Majorana Leaf Extract

Nelumbo Nucifera Germ Extract

Alcohol

Sodium Carboxymethyl Beta-Glucan

BHT

Thymus Serpyllum Extract

Perilla Ocymoides Leaf Extract

Sodium Bicarbonate

Iris Florentina Root Extract

Sodium Benzoate

Ganoderma Lucidum Stem Extract

Water, Alcohol Denat., Glycerin, Butylene Glycol, PEG/PPG-17/4 Dimethyl Ether, Triethylhexanoin, Cyclohexasiloxane, Dimethicone, Phenoxyethanol, Trehalose, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, PEG-14m, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate, PEG/PPG-14/7 Dimethyl Ether, Rosa Damascena Flower Water, Parfum, Disodium EDTA, Potassium Hydroxide, Silica, Isoceteth-10, Linalool, Lauryl Betaine, Ginkgo Biloba Leaf Extract, Geraniol, Citronellol, Origanum Majorana Leaf Extract, Nelumbo Nucifera Germ Extract, Alcohol, Sodium Carboxymethyl Beta-Glucan, BHT, Thymus Serpyllum Extract, Perilla Ocymoides Leaf Extract, Sodium Bicarbonate, Iris Florentina Root Extract, Sodium Benzoate, Ganoderma Lucidum Stem Extract

Pentylene Glycol

Niacinamide

Cetyl Alcohol

Isohexadecane

Isononyl Isononanoate

Diisopropyl Sebacate

2-Oleamido-1,3-Octadecanediol

4-T-Butylcyclohexanol

Acetyl Dipeptide-1 Cetyl Ester

Adenosine

Ceramide NP

Hydroxypalmitoyl Sphinganine

Lauroyl Lysine

Octyldodecanol

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Sodium Chloride

Sodium Hyaluronate

Sodium Hydroxide

Trisodium Ethylenediamine Disuccinate

Retinol

Tocopherol

Dicaprylyl Ether

Ammonium Polyacryloyldimethyl Taurate

Behenyl Alcohol

Caprylyl Glycol

Carbomer

Cetearyl Alcohol

Cetearyl Glucoside

Glycine Soja Oil

Helianthus Annuus Seed Oil

Hydroxyethylcellulose

Lecithin

Phenethyl Alcohol

Poloxamer 188

Polycaprolactone

Sorbitan Laurate

Steareth-100

CI 40800

Chlorphenesin

Water, Glycerin, Butylene Glycol, Pentylene Glycol, Niacinamide, Cetyl Alcohol, Isohexadecane, Isononyl Isononanoate, Diisopropyl Sebacate, 2-Oleamido-1,3-Octadecanediol, 4-T-Butylcyclohexanol, Acetyl Dipeptide-1 Cetyl Ester, Adenosine, Ceramide NP, Hydroxypalmitoyl Sphinganine, Lauroyl Lysine, Octyldodecanol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Chloride, Sodium Hyaluronate, Sodium Hydroxide, Trisodium Ethylenediamine Disuccinate, Retinol, Tocopherol, Dicaprylyl Ether, Ammonium Polyacryloyldimethyl Taurate, Behenyl Alcohol, Caprylyl Glycol, Carbomer, Cetearyl Alcohol, Cetearyl Glucoside, Glycine Soja Oil, Helianthus Annuus Seed Oil, Hydroxyethylcellulose, Lecithin, Phenethyl Alcohol, Poloxamer 188, Polycaprolactone, Sorbitan Laurate, Steareth-100, CI 40800, Chlorphenesin, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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