Sidmool Galatokside Real N.M.F Barrier Serum Versus Isntree Ultra-Low Molecular Hyaluronic Acid Serum

Sidmool Galatokside Real N.M.F Barrier Serum Versus Isntree Ultra-Low Molecular Hyaluronic Acid Serum

This barrier-repair serum is formulated around Galactomyces Ferment Filtrate and Sodium PCA to strengthen the skin barrier and hydrate skin.

This hydrating serum is formulated around Panthenol and Hydrolyzed Hyaluronic Acid to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Galactomyces Ferment Filtrate 71%

Sodium PCA

Sodium Lactate

Urea

Pentylene Glycol

Glycosaminoglycans

Glycerin

Butylene Glycol

Polyglutamic Acid

Hyaluronic Acid

Sodium Hyaluronate

Oligopeptide-1

Rh-Polypeptide-11

Sh-Oligopeptide-2

Madecassoside

Madecassic Acid

Asiaticoside

Asiatic Acid

Rosa Damascena Callus Culture Extract

Allantoin

Adenosine

Dipotassium Glycyrrhizate

1,2-Hexanediol

Heptyl Glucoside

Galactomyces Ferment Filtrate 71%, Sodium PCA, Sodium Lactate, Urea, Pentylene Glycol, Glycosaminoglycans, Glycerin, Butylene Glycol, Polyglutamic Acid, Hyaluronic Acid, Sodium Hyaluronate, Oligopeptide-1, Rh-Polypeptide-11, Sh-Oligopeptide-2, Madecassoside, Madecassic Acid, Asiaticoside, Asiatic Acid, Rosa Damascena Callus Culture Extract, Allantoin, Adenosine, Dipotassium Glycyrrhizate, 1,2-Hexanediol, Heptyl Glucoside

Sea Water

Water

Methylpropanediol

Betaine

Carbomer

Caprylyl Glycol

Tromethamine

Ethylhexylglycerin

Xanthan Gum

Panthenol

Malachite Extract

Hydrolyzed Hyaluronic Acid

Disodium EDTA

Glyceryl Acrylate/Acrylic Acid Copolymer

Glyceryl Glucoside

Potassium Hyaluronate

Hydrolyzed Sodium Hyaluronate

Sodium Acetylated Hyaluronate

Hydroxypropyltrimonium Hyaluronate

Sodium Hyaluronate Crosspolymer

Dimethylsilanol Hyaluronate

Hydrolyzed Calcium Hyaluronate

Sodium Sulfated Hyaluronate

Beta-Glucan

Sodium Stearoyl Hyaluronate

Sodium Oleoyl Hyaluronate

Sea Water, Water, Methylpropanediol, Glycerin, Butylene Glycol, 1,2-Hexanediol, Betaine, Pentylene Glycol, Carbomer, Caprylyl Glycol, Allantoin, Tromethamine, Ethylhexylglycerin, Xanthan Gum, Panthenol, Malachite Extract, Hydrolyzed Hyaluronic Acid, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Glyceryl Glucoside, Sodium Hyaluronate, Potassium Hyaluronate, Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Dimethylsilanol Hyaluronate, Hydrolyzed Calcium Hyaluronate, Sodium Sulfated Hyaluronate, Madecassoside, Beta-Glucan, Sodium Stearoyl Hyaluronate, Sodium Oleoyl Hyaluronate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Madecassoside is one of four active compounds found in Centella asiatica and is one of the main reasons Centella is so effective at calming irritated skin and supporting the moisture barrier.

There's a solid body of peer-reviewed research backing Madecassoside for several skin benefits. Studies have found:

Madecassoside pairs well with other hydrating or antioxidant ingredients like Ascorbic Acid or Hyaluronic Acid.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

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