Skin science article
Skin Deva Matrixyl 3000 + Hyaluronic Acid Serum Versus Cos De BAHA PT M.A. Peptide Facial Toner
Skin Deva Matrixyl 3000 + Hyaluronic Acid Serum Versus Cos De BAHA PT M.A. Peptide Facial Toner This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and hydrate skin. This anti-aging toner
Skin Deva Matrixyl 3000 + Hyaluronic Acid Serum Versus Cos De BAHA PT M.A. Peptide Facial Toner
This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and hydrate skin.
This anti-aging toner is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Acetyl Hexapeptide-8
Palmitoyl Pentapeptide-4
Aloe Barbadensis Leaf
Glycerin
Hyaluronic Acid
Benzyl Alcohol
Dehydroacetic Acid
Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Aloe Barbadensis Leaf, Glycerin, Hyaluronic Acid, Benzyl Alcohol, Dehydroacetic Acid
Aloe Barbadensis Leaf Extract
Propanediol
1,2-Hexanediol
Betaine
Sodium Hyaluronate
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Beta-Glucan
Allantoin
Rosa Damascena Extract
Lavandula Angustifolia Flower Extract
Camellia Sinensis Leaf Extract
Melissa Officinalis Leaf Extract
Artemisia Vulgaris Extract
Aloe Barbadensis Leaf Extract, Propanediol, Glycerin, 1,2-Hexanediol, Betaine, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Hexapeptide-8, Beta-Glucan, Allantoin, Rosa Damascena Extract, Lavandula Angustifolia Flower Extract, Camellia Sinensis Leaf Extract, Melissa Officinalis Leaf Extract, Artemisia Vulgaris Extract
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.