SkinBetter Science Intensive AlphaRet Overnight Cream Versus Paula's Choice Pro Retinaldehyde Dual-Retinoid Treatment

SkinBetter Science Intensive AlphaRet Overnight Cream Versus Paula's Choice Pro Retinaldehyde Dual-Retinoid Treatment

This anti-aging treatment is formulated around Glycolic Acid and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.

This anti-aging treatment is formulated around Retinal and Oleyl Adapalenate to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycolic Acid

Sodium Glycolate

Cetearyl Olivate

Pentylene Glycol

Cyclopentasiloxane

Isohexadecane

Sorbitan Olivate

Tetrahexyldecyl Ascorbate

Glycerin

Ceresin

Glycol Palmitate

Butylene Glycol

Niacinamide

Squalane

Methyl Gluceth-20

Ethyl Lactyl Retinoate

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Ceramide NP

Hyaluronic Acid

Ubiquinone

Tocopherol

Bisabolol

Tocopheryl Acetate

Superoxide Dismutase

Butyrospermum Parkii Butter

Allantoin Glycyrrhetinic Acid

Sodium PCA

Panthenol

Camellia Sinensis Leaf Extract

Portulaca Oleracea Extract

Linoleic Acid

Cholesterol

Linolenic Acid

Magnesium Aluminum Silicate

Dimethyl Isosorbide

Dimethicone

Glyceryl Stearate

PEG-100 Stearate

Steareth-2

Hydroxyethylcellulose

Acacia Senegal Gum

Xanthan Gum

Hydrated Silica

Carbomer

Polysorbate 20

Tromethamine

Disodium EDTA

Ethylhexylglycerin

Phenoxyethanol

CI 77891

Water, Glycolic Acid, Sodium Glycolate, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, CI 77891

Caprylic/Capric Triglyceride

Simmondsia Chinensis Seed Oil

Polyglyceryl-2 Stearate

Propanediol

Polyglyceryl-3 Diisostearate

Sodium Stearoyl Glutamate

Retinal

Oleyl Adapalenate

Saccharomyces Ferment Filtrate

Albatrellus Confluens Extract

Punica Granatum Pericarp Extract

Stearyl Alcohol

Hydroxyapatite

Cetyl Glyceryl Ether

Ricinus Communis Seed Oil

Sodium Polyacrylate

Isopropyl Myristate

Hydroxyacetophenone

Caprylhydroxamic Acid

Sodium Phytate

Hydroxystearic Acid

Ceramide AP

1,2-Hexanediol

Sorbitan Oleate

Naringin

Citric Acid

Titanium Dioxide

Water, Caprylic/Capric Triglyceride, Simmondsia Chinensis Seed Oil, Dimethicone, Polyglyceryl-2 Stearate, Propanediol, Polyglyceryl-3 Diisostearate, Sodium Stearoyl Glutamate, Retinal, Oleyl Adapalenate, Tocopherol, Tocopheryl Acetate, Saccharomyces Ferment Filtrate, Albatrellus Confluens Extract, Punica Granatum Pericarp Extract, Glyceryl Stearate, Stearyl Alcohol, Hydroxyapatite, Butylene Glycol, Cetyl Glyceryl Ether, Ricinus Communis Seed Oil, Sodium Polyacrylate, Isopropyl Myristate, Hydroxyacetophenone, Caprylhydroxamic Acid, Sodium Phytate, Xanthan Gum, Glycerin, Hydroxystearic Acid, Ceramide AP, 1,2-Hexanediol, Sorbitan Oleate, Naringin, Citric Acid, Titanium Dioxide

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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