Skin science article
SkinCeuticals Triple Lipid Restore 2:4:2 Versus First Aid Beauty Ultra Repair Face Moisturizer
SkinCeuticals Triple Lipid Restore 2:4:2 Versus First Aid Beauty Ultra Repair Face Moisturizer This barrier-repair moisturizer is formulated around Cholesterol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. This barrier-repair
SkinCeuticals Triple Lipid Restore 2:4:2 Versus First Aid Beauty Ultra Repair Face Moisturizer
This barrier-repair moisturizer is formulated around Cholesterol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.
This barrier-repair moisturizer is formulated around Avena Sativa Kernel Flour and Squalane to strengthen the skin barrier and calm redness.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dimethicone
Hydrogenated Polyisobutene
Glycerin
Cholesterol
C12-15 Alkyl Benzoate
Ceramide NP
Helianthus Annuus Seed Oil Unsaponifiables
Bis-PEG-18 Methyl Ether Dimethyl Silane
Sodium Polyacrylate
PEG-10 Dimethicone
Nylon-12
Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
Dimethicone/PEG-10/15 Crosspolymer
Phenoxyethanol
Disteardimonium Hectorite
Hydroxyethylpiperazine Ethane Sulfonic Acid
Ammonium Polyacryloyldimethyl Taurate
Chlorphenesin
Caprylyl Glycol
PEG/PPG-18/18 Dimethicone
Propylene Carbonate
Disodium EDTA
Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer
Adenosine
Dipropylene Glycol
Lavandula Angustifolia Oil
Rosmarinus Officinalis Leaf Oil
T-Butyl Alcohol
Mentha Piperita Oil
Sodium Citrate
Linalool
Isobutane
Ceramide EOP
BHT
Tocopherol
Limonene
Water, Dimethicone, Hydrogenated Polyisobutene, Glycerin, Cholesterol, C12-15 Alkyl Benzoate, Ceramide NP, Helianthus Annuus Seed Oil Unsaponifiables, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sodium Polyacrylate, PEG-10 Dimethicone, Nylon-12, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Phenoxyethanol, Disteardimonium Hectorite, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ammonium Polyacryloyldimethyl Taurate, Chlorphenesin, Caprylyl Glycol, PEG/PPG-18/18 Dimethicone, Propylene Carbonate, Disodium EDTA, Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer, Adenosine, Dipropylene Glycol, Lavandula Angustifolia Oil, Rosmarinus Officinalis Leaf Oil, T-Butyl Alcohol, Mentha Piperita Oil, Sodium Citrate, Linalool, Isobutane, Ceramide EOP, BHT, Tocopherol, Limonene
Glyceryl Stearate Se
Caprylic/Capric Triglyceride
Urea
Cetyl Alcohol
Avena Sativa Kernel Flour
Squalane
Butyrospermum Parkii Butter
Allantoin
Persea Gratissima Oil
N-Butyl Alcohol
Carbomer
Chrysanthemum Parthenium Extract
Camellia Sinensis Leaf Extract
Glycyrrhiza Glabra Root Extract
Sodium Hydroxide
Leuconostoc/Radish Root Ferment Filtrate
Tetrasodium EDTA
Water, Glyceryl Stearate Se, Glycerin, Caprylic/Capric Triglyceride, Dimethicone, Urea, Cetyl Alcohol, Avena Sativa Kernel Flour, Squalane, Caprylyl Glycol, Butyrospermum Parkii Butter, Allantoin, Persea Gratissima Oil, N-Butyl Alcohol, Carbomer, Chrysanthemum Parthenium Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Sodium Hydroxide, Ceramide NP, Leuconostoc/Radish Root Ferment Filtrate, Phenoxyethanol, Tetrasodium EDTA
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!