Skin science article
SkinCity Skincare Clearing 10% Azelaic Acid Serum Versus Allies of Skin Azelaic & Kojic Advanced Clarifying Serum
SkinCity Skincare Clearing 10% Azelaic Acid Serum Versus Allies of Skin Azelaic & Kojic Advanced Clarifying Serum This acne serum is formulated around Azelaic Acid and Centella Asiatica Flower/Leaf/Stem Extract to clear breakouts and calm redness. This brighte
SkinCity Skincare Clearing 10% Azelaic Acid Serum Versus Allies of Skin Azelaic & Kojic Advanced Clarifying Serum
This acne serum is formulated around Azelaic Acid and Centella Asiatica Flower/Leaf/Stem Extract to clear breakouts and calm redness.
This brightening serum is formulated around Azelaic Acid and Kojic Acid to fade the look of dark spots and clear breakouts.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Azelaic Acid
Isopropyl Isostearate
Glycerin
Centella Asiatica Flower/Leaf/Stem Extract
Triticum Monococcum Stem Water
Phenoxyethanol
Sclerotium Gum
Lysolecithin
Butylene Glycol
Xanthan Gum
Pullulan
Glycyrrhiza Glabra Root Extract
PEG-40 Hydrogenated Castor Oil
Bisabolol
Ganoderma Lucidum Extract
Ethylhexylglycerin
Silica
Propanediol
Biosaccharide Gum-1
Caprylyl Glycol
1,2-Hexanediol
Citric Acid
Sodium Benzoate
Potassium Sorbate
Water, Azelaic Acid, Isopropyl Isostearate, Glycerin, Centella Asiatica Flower/Leaf/Stem Extract, Triticum Monococcum Stem Water, Phenoxyethanol, Sclerotium Gum, Lysolecithin, Butylene Glycol, Xanthan Gum, Pullulan, Glycyrrhiza Glabra Root Extract, PEG-40 Hydrogenated Castor Oil, Bisabolol, Ganoderma Lucidum Extract, Ethylhexylglycerin, Silica, Propanediol, Biosaccharide Gum-1, Caprylyl Glycol, 1,2-Hexanediol, Citric Acid, Sodium Benzoate, Potassium Sorbate
Aloe Barbadensis Leaf Juice
Caprylic/Capric Triglyceride
Kojic Acid
Polysorbate 20
Hexylresorcinol
Ethyl Linoleate
Leuconostoc/Radish Root Ferment Filtrate
Dodecane
Hydroxyethylcellulose
Helianthus Annuus Seed Oil
Squalane
Glyceryl Laurate
Glyceryl Undecylenate
Allantoin
Ribose
Sodium Acetate
Bakuchiol
Cellulose
Water, Azelaic Acid, Butylene Glycol, Aloe Barbadensis Leaf Juice, Propanediol, Caprylic/Capric Triglyceride, Kojic Acid, Polysorbate 20, Glycerin, Caprylyl Glycol, Hexylresorcinol, Ethyl Linoleate, Leuconostoc/Radish Root Ferment Filtrate, Dodecane, Hydroxyethylcellulose, Xanthan Gum, Helianthus Annuus Seed Oil, Squalane, Bisabolol, Glyceryl Laurate, Glyceryl Undecylenate, Allantoin, Ribose, Sodium Acetate, Bakuchiol, Glycyrrhiza Glabra Root Extract, Cellulose, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.
What makes it special?
OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.
Here's what each tier does best:
Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.
Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.
Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.
It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.
A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.
In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.
You'll likely see use concentrations quite low, usually 0.1-0.2%.
Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.