Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Skinfix Barrier+ Triple Lipid-Peptide Cream Versus Biossance Squalane + Vitamin C Rose Moisturizer

Skinfix Barrier+ Triple Lipid-Peptide Cream Versus Biossance Squalane + Vitamin C Rose Moisturizer This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin. This brightenin

Skinfix Barrier+ Triple Lipid-Peptide Cream Versus Biossance Squalane + Vitamin C Rose Moisturizer

This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin.

This brightening moisturizer is formulated around Squalane and Tetrahexyldecyl Ascorbate to brighten dull-looking skin and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Caprylic/Capric Triglyceride

Glycerin

Butyrospermum Parkii Butter

Olus Oil

Cetyl Lactate

Propanediol

C12-16 Alcohols

Caprylyl Caprylate/Caprate

Jojoba Oil/Macadamia Seed Oil Esters

Glyceryl Stearate Citrate

Palmitic Acid

Hydrogenated Lecithin

Oryza Sativa Bran Extract

Dilinoleic Acid/Propanediol Copolymer

Squalene

Ophiopogon Japonicus Root Extract

Xanthan Gum

Phytosteryl Sunflowerseedate

Glycine Soja Extract

Pentylene Glycol

Ceramide NP

Ceramide AP

Ceramide EOP

Hydrolyzed Rice Protein

Chondrus Crispus Extract

Hydrogenated Vegetable Glycerides

Helianthus Annuus Extract

Sodium Hyaluronate

Citric Acid

Phytosteryl Macadamiate

Tocopherol

Rosmarinus Officinalis Leaf Extract

Aloe Barbadensis Leaf Juice

Trisodium Ethylenediamine Disuccinate

Phytosterols

Sodium Lauroyl Lactylate

Gluconolactone

Phenethyl Alcohol

Phytosphingosine

Cholesterol

Carbomer

Potassium Sorbate

Ethylhexylglycerin

Sodium Benzoate

Phenoxyethanol

Water, Caprylic/Capric Triglyceride, Glycerin, Butyrospermum Parkii Butter, Olus Oil, Cetyl Lactate, Propanediol, C12-16 Alcohols, Caprylyl Caprylate/Caprate, Jojoba Oil/Macadamia Seed Oil Esters, Glyceryl Stearate Citrate, Palmitic Acid, Hydrogenated Lecithin, Oryza Sativa Bran Extract, Dilinoleic Acid/Propanediol Copolymer, Squalene, Ophiopogon Japonicus Root Extract, Xanthan Gum, Phytosteryl Sunflowerseedate, Glycine Soja Extract, Pentylene Glycol, Ceramide NP, Ceramide AP, Ceramide EOP, Hydrolyzed Rice Protein, Chondrus Crispus Extract, Hydrogenated Vegetable Glycerides, Helianthus Annuus Extract, Sodium Hyaluronate, Citric Acid, Phytosteryl Macadamiate, Tocopherol, Rosmarinus Officinalis Leaf Extract, Aloe Barbadensis Leaf Juice, Trisodium Ethylenediamine Disuccinate, Phytosterols, Sodium Lauroyl Lactylate, Gluconolactone, Phenethyl Alcohol, Phytosphingosine, Cholesterol, Carbomer, Potassium Sorbate, Ethylhexylglycerin, Sodium Benzoate, Phenoxyethanol

Squalane

Isoamyl Laurate

Cetearyl Olivate

Sorbitan Olivate

Tetrahexyldecyl Ascorbate

Lactobacillus/Lemon Peel Ferment Extract

Glyceryl Stearate Se

Rosa Damascena Flower Extract

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Leuconostoc/Radish Root Ferment Filtrate

Cetyl Alcohol

Acacia Senegal Gum

Phytic Acid

Sodium Gluconate

Sodium Hydroxide

Citronellol

CI 77491

Water, Squalane, Glycerin, Caprylic/Capric Triglyceride, Isoamyl Laurate, Cetearyl Olivate, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Lactobacillus/Lemon Peel Ferment Extract, Tocopherol, Glyceryl Stearate Se, Rosa Damascena Flower Extract, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Leuconostoc/Radish Root Ferment Filtrate, Cetyl Alcohol, Acacia Senegal Gum, Xanthan Gum, Ethylhexylglycerin, Phytic Acid, Sodium Gluconate, Phenoxyethanol, Citric Acid, Sodium Hydroxide, Citronellol, CI 77491

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03We don't have a description for C12-16 Alcohols yet.
  4. 04Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
  5. 05Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
  6. 06In practice, that translates to a long shelf life and a consistently elegant skin feel.
  7. 07While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
  8. 08Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
  9. 09This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
  10. 10This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures…
  11. 11Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  12. 12Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  13. 13It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  14. 14Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
  15. 15A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
  16. 16Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.
  17. 17You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.
  18. 18The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.
  19. 19Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.
  20. 20Ceramide EOP is formally known as Ceramide 1.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side