Skin science article
Skinfix Barrier+ Triple Lipid-Peptide Cream Versus Epionce Renewal Facial Lotion
Skinfix Barrier+ Triple Lipid-Peptide Cream Versus Epionce Renewal Facial Lotion This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer i
Skinfix Barrier+ Triple Lipid-Peptide Cream Versus Epionce Renewal Facial Lotion
This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin.
This barrier-repair moisturizer is formulated around Petrolatum and Carthamus Tinctorius Seed Oil to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Caprylic/Capric Triglyceride
Glycerin
Butyrospermum Parkii Butter
Olus Oil
Cetyl Lactate
Propanediol
C12-16 Alcohols
Caprylyl Caprylate/Caprate
Jojoba Oil/Macadamia Seed Oil Esters
Glyceryl Stearate Citrate
Palmitic Acid
Hydrogenated Lecithin
Oryza Sativa Bran Extract
Dilinoleic Acid/Propanediol Copolymer
Squalene
Ophiopogon Japonicus Root Extract
Xanthan Gum
Phytosteryl Sunflowerseedate
Glycine Soja Extract
Pentylene Glycol
Ceramide NP
Ceramide AP
Ceramide EOP
Hydrolyzed Rice Protein
Chondrus Crispus Extract
Hydrogenated Vegetable Glycerides
Helianthus Annuus Extract
Sodium Hyaluronate
Citric Acid
Phytosteryl Macadamiate
Tocopherol
Rosmarinus Officinalis Leaf Extract
Aloe Barbadensis Leaf Juice
Trisodium Ethylenediamine Disuccinate
Phytosterols
Sodium Lauroyl Lactylate
Gluconolactone
Phenethyl Alcohol
Phytosphingosine
Cholesterol
Carbomer
Potassium Sorbate
Ethylhexylglycerin
Sodium Benzoate
Phenoxyethanol
Water, Caprylic/Capric Triglyceride, Glycerin, Butyrospermum Parkii Butter, Olus Oil, Cetyl Lactate, Propanediol, C12-16 Alcohols, Caprylyl Caprylate/Caprate, Jojoba Oil/Macadamia Seed Oil Esters, Glyceryl Stearate Citrate, Palmitic Acid, Hydrogenated Lecithin, Oryza Sativa Bran Extract, Dilinoleic Acid/Propanediol Copolymer, Squalene, Ophiopogon Japonicus Root Extract, Xanthan Gum, Phytosteryl Sunflowerseedate, Glycine Soja Extract, Pentylene Glycol, Ceramide NP, Ceramide AP, Ceramide EOP, Hydrolyzed Rice Protein, Chondrus Crispus Extract, Hydrogenated Vegetable Glycerides, Helianthus Annuus Extract, Sodium Hyaluronate, Citric Acid, Phytosteryl Macadamiate, Tocopherol, Rosmarinus Officinalis Leaf Extract, Aloe Barbadensis Leaf Juice, Trisodium Ethylenediamine Disuccinate, Phytosterols, Sodium Lauroyl Lactylate, Gluconolactone, Phenethyl Alcohol, Phytosphingosine, Cholesterol, Carbomer, Potassium Sorbate, Ethylhexylglycerin, Sodium Benzoate, Phenoxyethanol
Butylene Glycol
Trisiloxane
Petrolatum
Carthamus Tinctorius Seed Oil
PPG-2 Myristyl Ether Propionate
C10-30 Cholesterol/Lanosterol Esters
Limnanthes Alba Seed Oil
Laureth-7
C13-14 Isoparaffin
Polyacrylamide
Beeswax
C12-15 Alkyl Benzoate
Caprylyl Glycol
Cetyl Alcohol
Citrus Aurantium Dulcis Peel Oil
Citrus Limon Peel Oil
Cymbopogon Citratus Leaf/Stem Oil
Ethylene Brassylate
Glyceryl Stearate
Hexylene Glycol
Lavandula Hybrida Oil
Linalool
Linalyl Acetate
Linum Usitatissimum Seed Oil
Litsea Cubeba Fruit Oil
Malic Acid
Octanal
Olea Europaea Fruit Oil
PEG-100 Stearate
Persea Gratissima Oil
Phoenix Dactylifera Fruit Extract
Pyrus Malus Fruit Extract
Quercetin
Rosa Canina Fruit Oil
Sodium Hydroxide
Water, Butylene Glycol, Trisiloxane, Petrolatum, Carthamus Tinctorius Seed Oil, Glycerin, PPG-2 Myristyl Ether Propionate, C10-30 Cholesterol/Lanosterol Esters, Limnanthes Alba Seed Oil, Laureth-7, C13-14 Isoparaffin, Polyacrylamide, Beeswax, C12-15 Alkyl Benzoate, Caprylyl Glycol, Cetyl Alcohol, Citrus Aurantium Dulcis Peel Oil, Citrus Limon Peel Oil, Cymbopogon Citratus Leaf/Stem Oil, Ethylene Brassylate, Ethylhexylglycerin, Glyceryl Stearate, Hexylene Glycol, Lavandula Hybrida Oil, Linalool, Linalyl Acetate, Linum Usitatissimum Seed Oil, Litsea Cubeba Fruit Oil, Malic Acid, Octanal, Olea Europaea Fruit Oil, PEG-100 Stearate, Persea Gratissima Oil, Phenoxyethanol, Phoenix Dactylifera Fruit Extract, Phytosphingosine, Phytosterols, Pyrus Malus Fruit Extract, Quercetin, Rosa Canina Fruit Oil, Sodium Hyaluronate, Sodium Hydroxide
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Phytosphingosine is a phospholipid naturally found in our skin as a building block for ceramides.. It helps moisturize, soothe, and protect skin.
Phytosphingosine contributes to your skin's natural moisturizing factor (NMF). The NMF is responsible for hydration, a strong barrier, and plasticity. Our NMF decreases with age. Increasing NMF leads to more healthy and hydrated skin.
Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.
Fun fact: Phytosphingosine is abundant in plants and fungi.
More ingredients that help boost collagen in skin:
Phytosterols are plant-derived sterols (you can think of them as the plant world's version of cholesterol). In cosmetics, this ingredient is usually sourced from soybean, rice bran, shea, sunflower, and other seed oils.
The main actors in this group are β-sitosterol, campesterol, and stigmasterol (the CIR covers 27 phytosterols).
They work by fitting perfectly into your stratum corneum's lipid matrix since they're structurally similar to cholesterol. Here, they reinforce your skin's barrier.
One small in vivo human study showed topical soybean phytosterols sped up barrier recovery within three days on tape-stripped skin.
Broader research credits them with:
Formulation use typically sit under 5%.
Testing in soy-allergic subjects found no sensitization signals, but be sure to patch test if you are unsure or have existing allergies.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!