Skin science article
Skinfix Barrier+ Triple Lipid-Peptide Cream Versus Murad Retinol Youth Renewal Night Cream
Skinfix Barrier+ Triple Lipid-Peptide Cream Versus Murad Retinol Youth Renewal Night Cream This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin. This anti-aging night m
Skinfix Barrier+ Triple Lipid-Peptide Cream Versus Murad Retinol Youth Renewal Night Cream
This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin.
This anti-aging night moisturizer is formulated around Niacinamide and Retinol to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Caprylic/Capric Triglyceride
Glycerin
Butyrospermum Parkii Butter
Olus Oil
Cetyl Lactate
Propanediol
C12-16 Alcohols
Caprylyl Caprylate/Caprate
Jojoba Oil/Macadamia Seed Oil Esters
Glyceryl Stearate Citrate
Palmitic Acid
Hydrogenated Lecithin
Oryza Sativa Bran Extract
Dilinoleic Acid/Propanediol Copolymer
Squalene
Ophiopogon Japonicus Root Extract
Xanthan Gum
Phytosteryl Sunflowerseedate
Glycine Soja Extract
Pentylene Glycol
Ceramide NP
Ceramide AP
Ceramide EOP
Hydrolyzed Rice Protein
Chondrus Crispus Extract
Hydrogenated Vegetable Glycerides
Helianthus Annuus Extract
Sodium Hyaluronate
Citric Acid
Phytosteryl Macadamiate
Tocopherol
Rosmarinus Officinalis Leaf Extract
Aloe Barbadensis Leaf Juice
Trisodium Ethylenediamine Disuccinate
Phytosterols
Sodium Lauroyl Lactylate
Gluconolactone
Phenethyl Alcohol
Phytosphingosine
Cholesterol
Carbomer
Potassium Sorbate
Ethylhexylglycerin
Sodium Benzoate
Phenoxyethanol
Water, Caprylic/Capric Triglyceride, Glycerin, Butyrospermum Parkii Butter, Olus Oil, Cetyl Lactate, Propanediol, C12-16 Alcohols, Caprylyl Caprylate/Caprate, Jojoba Oil/Macadamia Seed Oil Esters, Glyceryl Stearate Citrate, Palmitic Acid, Hydrogenated Lecithin, Oryza Sativa Bran Extract, Dilinoleic Acid/Propanediol Copolymer, Squalene, Ophiopogon Japonicus Root Extract, Xanthan Gum, Phytosteryl Sunflowerseedate, Glycine Soja Extract, Pentylene Glycol, Ceramide NP, Ceramide AP, Ceramide EOP, Hydrolyzed Rice Protein, Chondrus Crispus Extract, Hydrogenated Vegetable Glycerides, Helianthus Annuus Extract, Sodium Hyaluronate, Citric Acid, Phytosteryl Macadamiate, Tocopherol, Rosmarinus Officinalis Leaf Extract, Aloe Barbadensis Leaf Juice, Trisodium Ethylenediamine Disuccinate, Phytosterols, Sodium Lauroyl Lactylate, Gluconolactone, Phenethyl Alcohol, Phytosphingosine, Cholesterol, Carbomer, Potassium Sorbate, Ethylhexylglycerin, Sodium Benzoate, Phenoxyethanol
Isostearyl Hydroxystearate
Niacinamide
C14-22 Alcohols
Polymethylsilsesquioxane
Dimethicone
Cetyl Alcohol
Glyceryl Stearate
Hydrolyzed Yeast Extract
Isopropyl Palmitate
Retinol
Retinyl Propionate
Oleyl Alcohol
Serine
Hexyldecanol
Tocopheryl Acetate
Glycine Soja Sterols
Urea
Yeast Amino Acids
Trehalose
Inositol
Taurine
Betaine
Polyglucuronic Acid
C12-20 Alkyl Glucoside
Dioscorea Villosa Root Extract
Glyceryl Polyacrylate
Algin
Caprylyl Glycol
Swertia Chirata Extract
Lecithin
Pullulan
Disodium Phosphate
Potassium Phosphate
PEG-75 Stearate
Ceteth-20
Steareth-20
Cetyl Hydroxyethylcellulose
Picolinamide
Disodium EDTA
Sodium Hydroxide
Hexylene Glycol
Sodium Benzotriazolyl Butylphenol Sulfonate
Ammonium Acryloyldimethyltaurate/Vp Copolymer
CI 19140
CI 14700
Alpha-Isomethyl Ionone
Citronellol
Parfum
Water, Isostearyl Hydroxystearate, Niacinamide, Propanediol, Caprylic/Capric Triglyceride, C14-22 Alcohols, Polymethylsilsesquioxane, Dimethicone, Cetyl Alcohol, Glyceryl Stearate, Hydrolyzed Yeast Extract, Isopropyl Palmitate, Retinol, Retinyl Propionate, Oleyl Alcohol, Sodium Hyaluronate, Serine, Hexyldecanol, Glycine Soja Extract, Tocopheryl Acetate, Glycine Soja Sterols, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Glycerin, Polyglucuronic Acid, C12-20 Alkyl Glucoside, Dioscorea Villosa Root Extract, Pentylene Glycol, Glyceryl Polyacrylate, Algin, Caprylyl Glycol, Swertia Chirata Extract, Lecithin, Pullulan, Disodium Phosphate, Potassium Phosphate, PEG-75 Stearate, Ceteth-20, Steareth-20, Cetyl Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Picolinamide, Disodium EDTA, Sodium Hydroxide, Hexylene Glycol, Sodium Benzotriazolyl Butylphenol Sulfonate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, CI 19140, CI 14700, Alpha-Isomethyl Ionone, Citronellol, Parfum
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
This ingredient comes from the wild soybean. It has skin conditioning and moisturizing properties due to its interesting bioactive compounds.
The two key bioactive compounds like genistein, daidzein, soybean trypsin inhibitor, Bowman-Birk inhibitor, and phenolic acids give it a broad range of studied effects.
Studies have shown soy proteins can inhibit melanin transfer to the skin's surface to potentially help with uneven skin tone. There's also some in-vitro evidence that soybean extract stimulate collagen and elastin synthesis. A 2025 mouse study found Glycine Soja leaf/stem extract reduced markers of atopic dermatitis-like inflammation and improved skin barrier function.
Just remember this ingredient still lacks robust human clinical trials. However, it would be a great supportive ingredient in any routine unless you have a known soy allergy.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!