Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Skintific 2% Salicylic Acid Anti Acne Serum Versus Paula's Choice 10% Azelaic Acid Booster

Skintific 2% Salicylic Acid Anti Acne Serum Versus Paula's Choice 10% Azelaic Acid Booster This acne serum is formulated around Niacinamide and Salicylic Acid to clear breakouts and refine the look of pores. This calming treatment is formulated around Azelaic

Skintific 2% Salicylic Acid Anti Acne Serum Versus Paula's Choice 10% Azelaic Acid Booster

This acne serum is formulated around Niacinamide and Salicylic Acid to clear breakouts and refine the look of pores.

This calming treatment is formulated around Azelaic Acid and Salicylic Acid to calm redness and fade the look of dark spots.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Niacinamide

Glycerin

PPG-10 Methyl Glucose Ether

Pentylene Glycol

1,2-Hexanediol

Salicylic Acid

Acacia Senegal Gum

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Triethanolamine

Methylpropanediol

Ectoin

Dipotassium Glycyrrhizate

Ceramide AP

Ceramide NP

Ceramide Ns

Ceramide Ng

Centella Asiatica Extract

Disodium EDTA

Tartaric Acid

Malic Acid

Peumus Boldus Leaf Extract

PPG-26-Buteth-26

Allantoin

O-Cymen-5-Ol

Ethylhexylglycerin

Glyceryl Caprylate

PEG-40 Hydrogenated Castor Oil

Menthol

Caprylyl Glycol

Xanthan Gum

Hydrolyzed Royal Jelly Protein

Oligopeptide-1

Sodium Hyaluronate

Glycolipids

Glycosphingolipids

Propanediol

Sodium Lactate

Glycolic Acid

Sucrose

Urea

Sodium Citrate

Phenoxyethanol

Water, Butylene Glycol, Niacinamide, Glycerin, PPG-10 Methyl Glucose Ether, Pentylene Glycol, 1,2-Hexanediol, Salicylic Acid, Acacia Senegal Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Triethanolamine, Methylpropanediol, Ectoin, Dipotassium Glycyrrhizate, Ceramide AP, Ceramide NP, Ceramide Ns, Ceramide Ng, Centella Asiatica Extract, Disodium EDTA, Tartaric Acid, Malic Acid, Peumus Boldus Leaf Extract, PPG-26-Buteth-26, Allantoin, O-Cymen-5-Ol, Ethylhexylglycerin, Glyceryl Caprylate, PEG-40 Hydrogenated Castor Oil, Menthol, Caprylyl Glycol, Xanthan Gum, Hydrolyzed Royal Jelly Protein, Oligopeptide-1, Sodium Hyaluronate, Glycolipids, Glycosphingolipids, Propanediol, Sodium Lactate, Glycolic Acid, Sucrose, Urea, Sodium Citrate, Phenoxyethanol

Azelaic Acid

C12-15 Alkyl Benzoate

Caprylic/Capric Triglyceride

Methyl Glucose Sesquistearate

Cetearyl Alcohol

Glyceryl Stearate

Dimethicone

Adenosine

Glycyrrhiza Glabra Root Extract

Boerhavia Diffusa Root Extract

Bisabolol

Cyclopentasiloxane

Sclerotium Gum

Water, Azelaic Acid, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Methyl Glucose Sesquistearate, Glycerin, Cetearyl Alcohol, Glyceryl Stearate, Dimethicone, Salicylic Acid, Adenosine, Glycyrrhiza Glabra Root Extract, Boerhavia Diffusa Root Extract, Allantoin, Bisabolol, Cyclopentasiloxane, Xanthan Gum, Sclerotium Gum, Propanediol, Butylene Glycol, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Salicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.

Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.

Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.

Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.

It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.

While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.

If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Glycerin
  3. 03Coco-Caprylate
  4. 04Butylene Glycol
  5. 05Propanediol
  6. 06Glyceryl Stearate
  7. 07Emblica Officinalis Fruit Extract
  8. 08Euterpe Oleracea Fruit Extract
  9. 09Vaccinium Macrocarpon Fruit Extract
  10. 10Vaccinium Myrtillus Fruit Extract
  11. 11Rubus Idaeus Fruit Extract
  12. 12Sambucus Nigra Fruit Extract
  13. 13Malpighia Emarginata Fruit Extract
  14. 14Hippophae Rhamnoides Fruit Extract
  15. 15Schisandra Chinensis Fruit Extract
  16. 16Rubus Chamaemorus Fruit Extract
  17. 17Lycium Barbarum Fruit Extract
  18. 18Plinia Cauliflora Fruit Extract
  19. 19Fragaria Vesca Fruit Extract
  20. 20Melia Azadirachta Flower Extract
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side