Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

SKKN BY KIM Hyaluronic Acid Serum Versus Hylamide SubQ Skin

SKKN BY KIM Hyaluronic Acid Serum Versus Hylamide SubQ Skin This hydrating serum is formulated around Aloe Barbadensis Leaf Juice and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier. This anti-aging serum is formulated around Palmitoyl Tripe

SKKN BY KIM Hyaluronic Acid Serum Versus Hylamide SubQ Skin

This hydrating serum is formulated around Aloe Barbadensis Leaf Juice and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Sodium Hyaluronate Crosspolymer to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Rosa Centifolia Flower Water

Aloe Barbadensis Leaf Juice

Glycerin

1,2-Hexanediol

Butylene Glycol

Saccharide Isomerate

Caprylyl Glycol

Citric Acid

Ethylhexylglycerin

Hydroxyacetophenone

Leuconostoc/Radish Root Ferment Filtrate

Myosotis Sylvatica Flower/Leaf/Stem Extract

Pentylene Glycol

Phytic Acid

Propanediol

Prunus Armeniaca Kernel Extract

Punica Granatum Fruit Juice

Sclerotium Gum

Sodium Citrate

Sodium Hyaluronate

Sodium Hydroxide

Vitis Vinifera Seed Oil

Chlorphenesin

Potassium Sorbate

Sodium Benzoate

Water, Rosa Centifolia Flower Water, Aloe Barbadensis Leaf Juice, Glycerin, 1,2-Hexanediol, Butylene Glycol, Saccharide Isomerate, Caprylyl Glycol, Citric Acid, Ethylhexylglycerin, Hydroxyacetophenone, Leuconostoc/Radish Root Ferment Filtrate, Myosotis Sylvatica Flower/Leaf/Stem Extract, Pentylene Glycol, Phytic Acid, Propanediol, Prunus Armeniaca Kernel Extract, Punica Granatum Fruit Juice, Sclerotium Gum, Sodium Citrate, Sodium Hyaluronate, Sodium Hydroxide, Vitis Vinifera Seed Oil, Chlorphenesin, Potassium Sorbate, Sodium Benzoate

Hydrolyzed Yeast Extract

Tamarindus Indica Seed Gum

Sodium Hyaluronate Crosspolymer

Palmitoyl Tripeptide-38

Myristoyl Nonapeptide-3

Copper Lysinate/Prolinate

Methylglucoside Phosphate

Hydrolyzed Sodium Hyaluronate

Ahnfeltia Concinna Extract

Polyglucuronic Acid

Lactobacillus/Eriodictyon Californicum Ferment Extract

Pseudoalteromonas Ferment Extract

Phospholipids

Lecithin

Hydroxypropyl Cyclodextrin

Cetyl Hydroxyethylcellulose

Polyacrylate Crosspolymer-6

Hexylene Glycol

Salicylic Acid

Trisodium Ethylenediamine Disuccinate

Ethoxydiglycol

Phenoxyethanol

Water, Glycerin, Hydrolyzed Yeast Extract, Pentylene Glycol, Tamarindus Indica Seed Gum, Sodium Hyaluronate Crosspolymer, Palmitoyl Tripeptide-38, Myristoyl Nonapeptide-3, Copper Lysinate/Prolinate, Methylglucoside Phosphate, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate, Ahnfeltia Concinna Extract, Saccharide Isomerate, Polyglucuronic Acid, Lactobacillus/Eriodictyon Californicum Ferment Extract, Pseudoalteromonas Ferment Extract, Phospholipids, Lecithin, Hydroxypropyl Cyclodextrin, Cetyl Hydroxyethylcellulose, Polyacrylate Crosspolymer-6, Hexylene Glycol, Salicylic Acid, Citric Acid, Sodium Citrate, Sodium Hydroxide, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Leuconostoc/Radish Root Ferment Filtrate, Sodium Benzoate, Potassium Sorbate, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol, Chlorphenesin

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc. The trade name for this ingredient is Leucidal.

Leuconostoc comes from lactic acid.

This ingredient has antimicrobial properties and helps prevent the growth of bacteria in a product.

Leuconostoc is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Saccharide Isomerate comes from sugars found in corn. It is a skin hydrator.

The structure of this ingredient can be altered to be more similar to the carbohydrates found in our skin. This ability to mimic our skin gives it hydrating properties.

Specifically, saccharide Isomerate is a humectant. Humectants draw moisture from the air to our skin.

Research shows Saccharide Isomerate to be an effective moisturizer.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

Its main functions are to maintain the pH of a product and neutralize metal ions.

The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).

Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Squalane
  2. 02Tetrahexyldecyl Ascorbate
  3. 03Caprylic/Capric Triglyceride
  4. 04Pistacia Lentiscus Gum
  5. 05Rosa Damascena Flower Extract
  6. 06Geraniol
  7. 07Citronellol
  8. 08Squalane, Tetrahexyldecyl Ascorbate, Caprylic/Capric Triglyceride, Pistacia Lentiscus Gum, Rosa Damascena Flower Extract, Geraniol, Citronellol
  9. 09Water
  10. 10Propanediol
  11. 11Sodium Hyaluronate
  12. 12Glycerin
  13. 13Butylene Glycol
  14. 14Phenoxyethanol
  15. 15Ammonium Acryloyldimethyltaurate/Vp Copolymer
  16. 16Leuconostoc/Radish Root Ferment Filtrate
  17. 17Hyaluronic Acid
  18. 18Carbomer
  19. 19Sodium Lactate
  20. 20Polysorbate 20
Source · skinsort.com
02

Product index

Related product references

Product

Omnilux Hyaluronic Acid Serum

Omnilux Hyaluronic Acid Serum Ingredients in Omnilux Hyaluronic Acid Serum explained: benefits, concerns, and detailed analysis of 21 ingredients including Water, Glycerin, and Propylene Gl…

Source: skinsort.comView reference →
03

Comparison edit

Read side by side

04

Ask the journal

Related questions

01Is Serum Good for All Skin Types?

Serums are a form of skincare that can be added to any routine no matter what your skin type is. All skin types can benefit from the use of a serum since there are so many different formulations that can target specific skincare concerns. “Serums are used for hydration,to aid [or] maintain the skin barrier, or treat skin issues like acne or rosacea,” says Dr. Lewis. The type of serum that you may use should depend on the skin issue you’re trying to target. Think of serums as a treatment for the skin. “Some serums can reverse damage and help prevent free radicals that cause the signs of aging skin,” adds Dr. Lewis.

Source · www.skincare.com
02When and How to Use Hyaluronic Acid in Your Routine

Products with hyaluronic acid can be used in the morning or at night (or both!). Applying the hydrating ingredient at night will restore your skin’s resilience while you sleep, and applying it in the morning will leave your skin feeling plump, hydrated and ready for makeup. Hyaluronic acid is great at providing topical hydration when it’s introduced into a balanced skincare routine. According to Dr. King, it’s important to pair your hyaluronic acid products with an emollient or occlusive moisturizer to lock in hydration.

Source · www.skincare.com