Skin science article
Stella by Stella McCartney Alter-Care Serum Versus Biossance Squalane + Copper Peptide Rapid Plumping Serum
Stella by Stella McCartney Alter-Care Serum Versus Biossance Squalane + Copper Peptide Rapid Plumping Serum This hydrating serum is formulated around Squalane and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier. This hydrating serum is formu
Stella by Stella McCartney Alter-Care Serum Versus Biossance Squalane + Copper Peptide Rapid Plumping Serum
This hydrating serum is formulated around Squalane and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.
This hydrating serum is formulated around Squalane and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Glycerin
Propanediol
Squalane
Caprylic/Capric Triglyceride
Pentylene Glycol
Polyglycerin-3
Maris Aqua
Sodium Hyaluronate
Vaccinium Vitis-Idaea Fruit Extract
Crithmum Maritimum Extract
Palmaria Palmata Extract
Hydrogenated Vegetable Oil
Tocopheryl Acetate
Tocopherol
Jojoba Esters
Xanthan Gum
Hydrogenated Coco-Glycerides
Hydroxyacetophenone
Cetearyl Glucoside
Sodium Stearoyl Glutamate
Alcaligenes Polysaccharides
Citric Acid
Sodium Citrate
Gluconolactone
Glucose
Calcium Gluconate
Caprylic/Capric/Succinic Triglyceride
Cetearyl Alcohol
Sodium Benzoate
Parfum
Water, Glycerin, Propanediol, Squalane, Caprylic/Capric Triglyceride, Pentylene Glycol, Polyglycerin-3, Maris Aqua, Sodium Hyaluronate, Vaccinium Vitis-Idaea Fruit Extract, Crithmum Maritimum Extract, Palmaria Palmata Extract, Hydrogenated Vegetable Oil, Tocopheryl Acetate, Tocopherol, Jojoba Esters, Xanthan Gum, Hydrogenated Coco-Glycerides, Hydroxyacetophenone, Cetearyl Glucoside, Sodium Stearoyl Glutamate, Alcaligenes Polysaccharides, Citric Acid, Sodium Citrate, Gluconolactone, Glucose, Calcium Gluconate, Caprylic/Capric/Succinic Triglyceride, Cetearyl Alcohol, Sodium Benzoate, Parfum
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Copper Tripeptide-1
Acmella Oleracea Extract
Ectoin
Tetrapeptide-30
Palmitoyl Hexapeptide-52
Copper PCA
Panthenol
Sodium Polyglutamate
Camellia Sinensis Leaf Extract
Aloe Barbadensis Flower Extract
Passiflora Incarnata Flower Extract
Melia Azadirachta Leaf Extract
Solanum Melongena Fruit Extract
Curcuma Longa Root Extract
Ocimum Basilicum Flower/Leaf Extract
Coccinia Indica Fruit Extract
Melia Azadirachta Flower Extract
Ocimum Sanctum Leaf Extract
Corallina Officinalis Extract
Polyacrylate Crosspolymer-6
Acacia Senegal Gum
Phenoxyethanol
Ethylhexylglycerin
Caprylyl Glycol
Water, Glycerin, Propanediol, Squalane, Sodium Hyaluronate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Copper Tripeptide-1, Acmella Oleracea Extract, Ectoin, Tetrapeptide-30, Palmitoyl Hexapeptide-52, Copper PCA, Panthenol, Sodium Polyglutamate, Camellia Sinensis Leaf Extract, Aloe Barbadensis Flower Extract, Passiflora Incarnata Flower Extract, Melia Azadirachta Leaf Extract, Solanum Melongena Fruit Extract, Curcuma Longa Root Extract, Ocimum Basilicum Flower/Leaf Extract, Coccinia Indica Fruit Extract, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin, Citric Acid, Caprylyl Glycol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.