Skin science article
Summer Fridays CC Me Vitamin C Serum Versus Allies of Skin 35% Vitamin C+ Perfecting Serum
Summer Fridays CC Me Vitamin C Serum Versus Allies of Skin 35% Vitamin C+ Perfecting Serum This brightening serum is formulated around Niacinamide and 3-O-Ethyl Ascorbic Acid to brighten dull-looking skin and fade the look of dark spots. This brightening serum
Summer Fridays CC Me Vitamin C Serum Versus Allies of Skin 35% Vitamin C+ Perfecting Serum
This brightening serum is formulated around Niacinamide and 3-O-Ethyl Ascorbic Acid to brighten dull-looking skin and fade the look of dark spots.
This brightening serum is formulated around 3-O-Ethyl Ascorbic Acid and Tetrahexyldecyl Ascorbate to brighten dull-looking skin and fade the look of dark spots.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Niacinamide
Butylene Glycol
3-O-Ethyl Ascorbic Acid
Ascorbyl Glucoside
Glycerin
Capryloyl Glycerin/Sebacic Acid Copolymer
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Squalane
Sodium Citrate
Phenoxyethanol
Sodium Hydroxide
Citric Acid
Diheptyl Succinate
Tocopheryl Acetate
Xanthan Gum
Tetrasodium Glutamate Diacetate
Carbomer
Polysorbate 20
Palmitoyl Oligopeptide
Palmitoyl Tetrapeptide-7
Camellia Oleifera Leaf Extract
Ethylhexylglycerin
Orchis Mascula Flower Extract
Caprylic/Capric Triglyceride
Cananga Odorata Flower Extract
Cucumis Melo Cantalupensis Fruit Extract
Eugenia Caryophyllus Flower Extract
Glycine Soja Oil
Pyrus Malus Fruit Extract
Prunus Armeniaca Fruit Extract
Rosa Gallica Flower Extract
Cinnamomum Cassia Bark Extract
Jasminum Officinale Flower/Leaf Extract
Coffea Arabica Leaf/Seed Extract
Camellia Sinensis Leaf Extract
Amyl Cinnamal
Cinnamyl Alcohol
Citronellol
Eugenol
Hydroxycitronellal
Water, Niacinamide, Butylene Glycol, 3-O-Ethyl Ascorbic Acid, Ascorbyl Glucoside, Glycerin, Capryloyl Glycerin/Sebacic Acid Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Sodium Citrate, Phenoxyethanol, Sodium Hydroxide, Citric Acid, Diheptyl Succinate, Tocopheryl Acetate, Xanthan Gum, Tetrasodium Glutamate Diacetate, Carbomer, Polysorbate 20, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Camellia Oleifera Leaf Extract, Ethylhexylglycerin, Orchis Mascula Flower Extract, Caprylic/Capric Triglyceride, Cananga Odorata Flower Extract, Cucumis Melo Cantalupensis Fruit Extract, Eugenia Caryophyllus Flower Extract, Glycine Soja Oil, Pyrus Malus Fruit Extract, Prunus Armeniaca Fruit Extract, Rosa Gallica Flower Extract, Cinnamomum Cassia Bark Extract, Jasminum Officinale Flower/Leaf Extract, Coffea Arabica Leaf/Seed Extract, Camellia Sinensis Leaf Extract, Amyl Cinnamal, Cinnamyl Alcohol, Citronellol, Eugenol, Hydroxycitronellal
Ethoxydiglycol
Tetrahexyldecyl Ascorbate
Dimethyl Isosorbide
Isodecyl Neopentanoate
Glutathione
Superoxide Dismutase
Caprylyl Glycol
Ethoxydiglycol, 3-O-Ethyl Ascorbic Acid, Tetrahexyldecyl Ascorbate, Dimethyl Isosorbide, Isodecyl Neopentanoate, Glutathione, Superoxide Dismutase, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
3-O-Ethyl Ascorbic Acid is one of the most popular "stable" vitamin C derivatives in skincare.
Plain ascorbic acid is fantastic but notoriously fragile; it browns, oxidizes, and loses potency fast. So attaching an ethyl group to the third carbon of the molecule gives it some cool perks:
In a formula, it does the 3 classic vitamin C jobs: it acts as an antioxidant, helps brighten skin tone by inhibiting tyrosinase, and supports collagen.
The evidence is reasonably solid for a cosmetic ingredient; Liao and colleagues (2018) showed it's significantly more stable than ascorbic acid while still being effective.
A 2021 study by Zerbinati and colleagues tested a serum with 30% 3-O-ethyl-l-ascorbic acid and 1% lactic acid significantly increased collagen production, reduced UVB-induced DNA damage, and decreased melanin on a reconstructed pigmented skin model.
Typical real world usage sits around 0.5-5% (and 1-2% is common for daily serums).
Amounts up to 30% have been shown to be non-irritating on human skin samples, but two isolated cases reported allergic contact dermatitis so a patch test is sensible if you have reactive skin.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.