Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Superdrug Me+ Caffeine Eye Cream Versus The INKEY List Caffeine Eye Cream

Superdrug Me+ Caffeine Eye Cream Versus The INKEY List Caffeine Eye Cream This anti-aging eye moisturizer is formulated around Caffeine and Coffea Arabica Seed Extract to soften the look of wrinkles. This anti-aging eye moisturizer is formulated around Caffein

Superdrug Me+ Caffeine Eye Cream Versus The INKEY List Caffeine Eye Cream

This anti-aging eye moisturizer is formulated around Caffeine and Coffea Arabica Seed Extract to soften the look of wrinkles.

This anti-aging eye moisturizer is formulated around Caffeine and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Caprylic/Capric Triglyceride

Propylene Glycol

Butyrospermum Parkii Butter

Isopropyl Myristate

Glyceryl Stearate

Dimethicone

Polyglyceryl-3 Methylglucose Distearate

Caffeine

Stearyl Alcohol

Phenoxyethanol

Coffea Arabica Seed Extract

Betaine

Stearic Acid

Caprylyl Glycol

Carbomer

Glycerin

Xanthan Gum

Butylene Glycol

Lecithin

Tocopheryl Acetate

Disodium EDTA

Sodium Hydroxide

Tetrapeptide-21

Water, Caprylic/Capric Triglyceride, Propylene Glycol, Butyrospermum Parkii Butter, Isopropyl Myristate, Glyceryl Stearate, Dimethicone, Polyglyceryl-3 Methylglucose Distearate, Caffeine, Stearyl Alcohol, Phenoxyethanol, Coffea Arabica Seed Extract, Betaine, Stearic Acid, Caprylyl Glycol, Carbomer, Glycerin, Xanthan Gum, Butylene Glycol, Lecithin, Tocopheryl Acetate, Disodium EDTA, Sodium Hydroxide, Tetrapeptide-21

Dicaprylyl Carbonate

Propanediol

Polyglyceryl-6 Distearate

Cetyl Alcohol

Glyceryl Behenate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Jojoba Esters

Albizia Julibrissin Bark Extract

Squalane

Polyglyceryl-3 Beeswax

Phospholipids

Ethylhexylglycerin

Glycine Soja Oil

Polysorbate 60

Sodium Phytate

Glycolipids

Sorbitan Isostearate

Citric Acid

Glycine Soja Sterols

Leuconostoc/Radish Root Ferment Filtrate

Hyaluronic Acid

Sodium Benzoate

Tocopherol

Darutoside

Sodium Lactate

Polysorbate 20

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Water, Glycerin, Dicaprylyl Carbonate, Propanediol, Polyglyceryl-6 Distearate, Cetyl Alcohol, Glyceryl Behenate, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Jojoba Esters, Albizia Julibrissin Bark Extract, Squalane, Caffeine, Polyglyceryl-3 Beeswax, Phospholipids, Ethylhexylglycerin, Xanthan Gum, Glycine Soja Oil, Polysorbate 60, Sodium Phytate, Glycolipids, Sorbitan Isostearate, Butylene Glycol, Citric Acid, Glycine Soja Sterols, Leuconostoc/Radish Root Ferment Filtrate, Hyaluronic Acid, Sodium Benzoate, Tocopherol, Carbomer, Darutoside, Sodium Lactate, Polysorbate 20, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.

As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.

Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.

You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.

Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.

Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.
  7. 07As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.
  8. 08Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.
  9. 09You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.
  10. 10Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.
  11. 11Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.
  12. 12Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
  13. 13Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
  14. 14However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
  15. 15Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
  16. 16In skincare formulas, citric acid can:
  17. 17While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
  18. 18Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
  19. 19Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
  20. 20However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's…
Source · skinsort.com
02

Product index

Related product references

Product

Tree to Tub Caffeine Eye Cream,

Tree to Tub Caffeine Eye Cream, Tree to Tub Caffeine Eye Cream, ingredients explained: Aqua, Glycerin (From Palm)*, Coco-Caprylate/Caprate (From Coconut), Caprylic / Capric Triglyceride (Fr…

Source: incidecoder.comView reference →

Product

John Jeff Caffeine Eye Cream

John Jeff Caffeine Eye Cream Ingredients in John Jeff Caffeine Eye Cream explained: benefits, concerns, and detailed analysis of 29 ingredients including Water, Niacinamide, and Caffeine A …

Source: skinsort.comView reference →
03

Comparison edit

Read side by side