Skin science article
Swisse Bio-Retinol 0.5% Vitamin B3 10% Renewing Booster Serum Versus rhode Peptide Glazing Fluid
Swisse Bio-Retinol 0.5% Vitamin B3 10% Renewing Booster Serum Versus rhode Peptide Glazing Fluid This anti-aging serum is formulated around Niacinamide and Bakuchiol to soften the look of wrinkles and refine skin texture. This barrier-repair serum is formulate
Swisse Bio-Retinol 0.5% Vitamin B3 10% Renewing Booster Serum Versus rhode Peptide Glazing Fluid
This anti-aging serum is formulated around Niacinamide and Bakuchiol to soften the look of wrinkles and refine skin texture.
This barrier-repair serum is formulated around Sclerocarya Birrea Seed Oil and Niacinamide to strengthen the skin barrier and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Niacinamide
Glycerin
Propanediol
Pentylene Glycol
Coco-Caprylate
PEG-7 Glyceryl Cocoate
Bakuchiol
Sodium Hyaluronate
Sodium Hyaluronate Crosspolymer
Sodium Acetylated Hyaluronate
Hydrolyzed Sodium Hyaluronate
C13-15 Alkane
Capryloyl Glycerin/Sebacic Acid Copolymer
Diheptyl Succinate
Glycine Soja Oil
Heptyl Undecylenate
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Disodium EDTA
Xanthan Gum
Heptyl Glucoside
Citric Acid
Sodium Hydroxide
Ethylhexylglycerin
Caprylyl Glycol
Phenoxyethanol
Water, Niacinamide, Glycerin, Propanediol, Pentylene Glycol, Coco-Caprylate, PEG-7 Glyceryl Cocoate, Bakuchiol, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, C13-15 Alkane, Capryloyl Glycerin/Sebacic Acid Copolymer, Diheptyl Succinate, Glycine Soja Oil, Heptyl Undecylenate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Disodium EDTA, Xanthan Gum, Heptyl Glucoside, Citric Acid, Sodium Hydroxide, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol
Butylene Glycol
Sclerocarya Birrea Seed Oil
Tetradecane
Benzyl Alcohol
Glyceryl Oleate
Sucrose Palmitate
Hydroxyacetophenone
Carbomer
Disodium Phosphate
Sodium Phosphate
Dilauryl Thiodipropionate
Acetyl Hexapeptide-8
Water, Butylene Glycol, Glycerin, Sclerocarya Birrea Seed Oil, Niacinamide, Tetradecane, Capryloyl Glycerin/Sebacic Acid Copolymer, Diheptyl Succinate, Benzyl Alcohol, Glyceryl Oleate, Sucrose Palmitate, Hydroxyacetophenone, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Sodium Hydroxide, Disodium Phosphate, Sodium Phosphate, Sodium Hyaluronate, Dilauryl Thiodipropionate, Acetyl Hexapeptide-8
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
We don't have a description for Capryloyl Glycerin/Sebacic Acid Copolymer yet.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
We don't have a description for Diheptyl Succinate yet.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!