Skin science article
The Derma Co Skin Renew Barrier Repair Peptide Moisturizer Versus Minimalist Ceramides 0.3% + Madecassoside
The Derma Co Skin Renew Barrier Repair Peptide Moisturizer Versus Minimalist Ceramides 0.3% + Madecassoside This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. This ba
The Derma Co Skin Renew Barrier Repair Peptide Moisturizer Versus Minimalist Ceramides 0.3% + Madecassoside
This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.
This barrier-repair moisturizer is formulated around Avena Sativa Kernel Extract and Madecassoside to strengthen the skin barrier and calm redness.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propanediol
Coco-Caprylate/Caprate
Cetearyl Alcohol
Niacinamide
Betaine
Cyclopentasiloxane
Neopentyl Glycol Diheptanoate
Isododecane
Squalane
3-O-Ethyl Ascorbic Acid
Ceramide NP
PEG-7 Glyceryl Cocoate
Phenoxyethanol
Ethylhexylglycerin
Glyceryl Stearate
Palmitoyl Tripeptide-5
Polyacrylate-13
Polyisobutene
Polysorbate 20
Glyceryl Stearate Citrate
Centella Asiatica Extract
Xylitylglucoside
Anhydroxylitol
Xylitol
Sodium Hyaluronate
Allantoin
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Triethanolamine
Sodium Gluconate
Water, Propanediol, Coco-Caprylate/Caprate, Cetearyl Alcohol, Niacinamide, Betaine, Cyclopentasiloxane, Neopentyl Glycol Diheptanoate, Isododecane, Squalane, 3-O-Ethyl Ascorbic Acid, Ceramide NP, PEG-7 Glyceryl Cocoate, Phenoxyethanol, Ethylhexylglycerin, Glyceryl Stearate, Palmitoyl Tripeptide-5, Polyacrylate-13, Polyisobutene, Polysorbate 20, Glyceryl Stearate Citrate, Centella Asiatica Extract, Xylitylglucoside, Anhydroxylitol, Xylitol, Sodium Hyaluronate, Allantoin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Triethanolamine, Sodium Gluconate
Avena Sativa Kernel Extract
Dicaprylyl Carbonate
Glycerin
Glyceryl Glucoside
Butylene Glycol
Trehalose
Saccharide Isomerate
Ursolic Acid
Aminobutyric Acid
Pentylene Glycol
Cholesterol
Hydrogenated Lecithin
Madecassoside
Sucrose Distearate
Propylene Glycol
Ceramide EOP
Ceramide Ns
Ceramide As
Ceramide AP
Citric Acid
Sodium Citrate
Carbomer
Trisodium Ethylenediamine Disuccinate
Water, Avena Sativa Kernel Extract, Dicaprylyl Carbonate, Glycerin, Glyceryl Glucoside, Butylene Glycol, Trehalose, Saccharide Isomerate, Ursolic Acid, Aminobutyric Acid, Pentylene Glycol, Allantoin, Cholesterol, Hydrogenated Lecithin, Madecassoside, Polyacrylate-13, Polyisobutene, Polysorbate 20, Glyceryl Stearate, Sucrose Distearate, Propylene Glycol, Phenoxyethanol, Ceramide NP, Ceramide EOP, Ceramide Ns, Ceramide As, Ceramide AP, Triethanolamine, Ethylhexylglycerin, Citric Acid, Sodium Citrate, Carbomer, Trisodium Ethylenediamine Disuccinate
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.
Polyacrylate-13 creates a film to protect the skin. It is also used to thicken and stabilize a product. It works by making water a gel-like consistency. This gel consistency helps suspend particles.
Polyacrylate-13 is a copolymer of acrylic acid, acrylamide, sodium acrylate, sodium acryloyldimethyltaurate monomers
Polyisobutene is a synthetic polymer made from isobutene.
It is a film-forming agent and helps bind ingredients together.
Polyisobutene is not absorbed by the skin.
Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Triethanolamine (TEA) is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.
As an emulsifier, it prevents ingredients from separating and enhances texture by adding volume to a product.
PH adjusters are common in cosmetic products. The pH of a product can affect the effectiveness of other ingredients. A product with a high pH may also irritate the skin.
If you are looking for the tea leaf ingredient, click here.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!