Skin science article
The Derma Co Skin Renew Barrier Repair Peptide Moisturizer Versus Skinfix Barrier+ Triple Lipid-Peptide Cream
The Derma Co Skin Renew Barrier Repair Peptide Moisturizer Versus Skinfix Barrier+ Triple Lipid-Peptide Cream This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. This
The Derma Co Skin Renew Barrier Repair Peptide Moisturizer Versus Skinfix Barrier+ Triple Lipid-Peptide Cream
This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.
This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propanediol
Coco-Caprylate/Caprate
Cetearyl Alcohol
Niacinamide
Betaine
Cyclopentasiloxane
Neopentyl Glycol Diheptanoate
Isododecane
Squalane
3-O-Ethyl Ascorbic Acid
Ceramide NP
PEG-7 Glyceryl Cocoate
Phenoxyethanol
Ethylhexylglycerin
Glyceryl Stearate
Palmitoyl Tripeptide-5
Polyacrylate-13
Polyisobutene
Polysorbate 20
Glyceryl Stearate Citrate
Centella Asiatica Extract
Xylitylglucoside
Anhydroxylitol
Xylitol
Sodium Hyaluronate
Allantoin
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Triethanolamine
Sodium Gluconate
Water, Propanediol, Coco-Caprylate/Caprate, Cetearyl Alcohol, Niacinamide, Betaine, Cyclopentasiloxane, Neopentyl Glycol Diheptanoate, Isododecane, Squalane, 3-O-Ethyl Ascorbic Acid, Ceramide NP, PEG-7 Glyceryl Cocoate, Phenoxyethanol, Ethylhexylglycerin, Glyceryl Stearate, Palmitoyl Tripeptide-5, Polyacrylate-13, Polyisobutene, Polysorbate 20, Glyceryl Stearate Citrate, Centella Asiatica Extract, Xylitylglucoside, Anhydroxylitol, Xylitol, Sodium Hyaluronate, Allantoin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Triethanolamine, Sodium Gluconate
Caprylic/Capric Triglyceride
Glycerin
Butyrospermum Parkii Butter
Olus Oil
Cetyl Lactate
C12-16 Alcohols
Caprylyl Caprylate/Caprate
Jojoba Oil/Macadamia Seed Oil Esters
Palmitic Acid
Hydrogenated Lecithin
Oryza Sativa Bran Extract
Dilinoleic Acid/Propanediol Copolymer
Squalene
Ophiopogon Japonicus Root Extract
Xanthan Gum
Phytosteryl Sunflowerseedate
Glycine Soja Extract
Pentylene Glycol
Ceramide AP
Ceramide EOP
Hydrolyzed Rice Protein
Chondrus Crispus Extract
Hydrogenated Vegetable Glycerides
Helianthus Annuus Extract
Citric Acid
Phytosteryl Macadamiate
Tocopherol
Rosmarinus Officinalis Leaf Extract
Aloe Barbadensis Leaf Juice
Trisodium Ethylenediamine Disuccinate
Phytosterols
Sodium Lauroyl Lactylate
Gluconolactone
Phenethyl Alcohol
Phytosphingosine
Cholesterol
Carbomer
Potassium Sorbate
Sodium Benzoate
Water, Caprylic/Capric Triglyceride, Glycerin, Butyrospermum Parkii Butter, Olus Oil, Cetyl Lactate, Propanediol, C12-16 Alcohols, Caprylyl Caprylate/Caprate, Jojoba Oil/Macadamia Seed Oil Esters, Glyceryl Stearate Citrate, Palmitic Acid, Hydrogenated Lecithin, Oryza Sativa Bran Extract, Dilinoleic Acid/Propanediol Copolymer, Squalene, Ophiopogon Japonicus Root Extract, Xanthan Gum, Phytosteryl Sunflowerseedate, Glycine Soja Extract, Pentylene Glycol, Ceramide NP, Ceramide AP, Ceramide EOP, Hydrolyzed Rice Protein, Chondrus Crispus Extract, Hydrogenated Vegetable Glycerides, Helianthus Annuus Extract, Sodium Hyaluronate, Citric Acid, Phytosteryl Macadamiate, Tocopherol, Rosmarinus Officinalis Leaf Extract, Aloe Barbadensis Leaf Juice, Trisodium Ethylenediamine Disuccinate, Phytosterols, Sodium Lauroyl Lactylate, Gluconolactone, Phenethyl Alcohol, Phytosphingosine, Cholesterol, Carbomer, Potassium Sorbate, Ethylhexylglycerin, Sodium Benzoate, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glyceryl Stearate Citrate is a citric acid ester of glyceryl stearate.
It is an emulsifier, emollient, and a surfactant.
Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating. Common ingredients include oils and water, which do not mix naturally. Emulsifiers have properties that help keep ingredients such as these together.
Emollients help soothe and soften the skin. They do this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.
Surfactants help gather oils, dirt, and other pollutants from the skin. This helps them to be easily rinsed away.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!