Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

The INKEY List 10% Urea Moisturizer Versus CeraVe Moisturizing Cream

The INKEY List 10% Urea Moisturizer Versus CeraVe Moisturizing Cream This smoothing moisturizer is formulated around Urea and Avena Sativa Kernel Flour to refine skin texture and hydrate skin. This barrier-repair moisturizer is formulated around Ceramide NP an

The INKEY List 10% Urea Moisturizer Versus CeraVe Moisturizing Cream

This smoothing moisturizer is formulated around Urea and Avena Sativa Kernel Flour to refine skin texture and hydrate skin.

This barrier-repair moisturizer is formulated around Ceramide NP and Ceramide AP to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Urea

Caprylic/Capric Triglyceride

Glycerin

Cetearyl Alcohol

Glyceryl Stearate Se

Avena Sativa Kernel Flour

Carthamus Tinctorius Seed Oil

Squalane

Phenoxyethanol

Benzyl Alcohol

Sodium Carbomer

Sodium Stearoyl Glutamate

Citric Acid

Ethylhexylglycerin

Sodium Gluconate

Dehydroacetic Acid

Water, Urea, Caprylic/Capric Triglyceride, Glycerin, Cetearyl Alcohol, Glyceryl Stearate Se, Avena Sativa Kernel Flour, Carthamus Tinctorius Seed Oil, Squalane, Phenoxyethanol, Benzyl Alcohol, Sodium Carbomer, Sodium Stearoyl Glutamate, Citric Acid, Ethylhexylglycerin, Sodium Gluconate, Dehydroacetic Acid

Cetyl Alcohol

Ceteareth-20

Petrolatum

Potassium Phosphate

Ceramide NP

Ceramide AP

Ceramide EOP

Carbomer

Dimethicone

Behentrimonium Methosulfate

Sodium Lauroyl Lactylate

Sodium Hyaluronate

Cholesterol

Disodium EDTA

Dipotassium Phosphate

Tocopherol

Phytosphingosine

Xanthan Gum

Water, Glycerin, Cetearyl Alcohol, Caprylic/Capric Triglyceride, Cetyl Alcohol, Ceteareth-20, Petrolatum, Potassium Phosphate, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Dimethicone, Behentrimonium Methosulfate, Sodium Lauroyl Lactylate, Sodium Hyaluronate, Cholesterol, Phenoxyethanol, Disodium EDTA, Dipotassium Phosphate, Tocopherol, Phytosphingosine, Xanthan Gum, Ethylhexylglycerin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Squalane
  3. 03Glycerin
  4. 04Propanediol
  5. 05Plukenetia Volubilis Seed Oil
  6. 06Dicaprylyl Carbonate
  7. 07Bakuchiol
  8. 08Phenoxyethanol
  9. 09Sodium Caproyl Prolinate
  10. 10Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
  11. 11Carbomer
  12. 12Sodium Hydroxide
  13. 13Ethylhexylglycerin
  14. 14Sodium Stearoyl Glutamate
  15. 15Polysorbate 60
  16. 16Phytic Acid
  17. 17Glyceryl Polyacrylate
  18. 18Sorbitan Isostearate
  19. 19Tocopherol
  20. 20Water, Squalane, Glycerin, Propanediol, Plukenetia Volubilis Seed Oil, Dicaprylyl Carbonate, Bakuchiol, Phenoxyethanol, Sodium Caproyl Prolinate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Carbomer, Sodium Hydroxide, Ethylhexyl…
Source · skinsort.com
02

Product index

Related product references

Product

The Inkey List Vitamin C Serum

The Inkey List Vitamin C Serum The Inkey List Vitamin C Serum ingredients explained: Dimethicone, Ascorbic Acid, Polysilicone-11, Peg-10 Dimethicone Show all ingredients by function Dimethi…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side