Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

The INKEY List Alpha Arbutin Serum Versus Clarins Double Serum Complete Age Control Concentrate

The INKEY List Alpha Arbutin Serum Versus Clarins Double Serum Complete Age Control Concentrate This brightening serum is formulated around Alpha-Arbutin to fade the look of dark spots and brighten dull-looking skin. This anti-aging serum is formulated around

The INKEY List Alpha Arbutin Serum Versus Clarins Double Serum Complete Age Control Concentrate

This brightening serum is formulated around Alpha-Arbutin to fade the look of dark spots and brighten dull-looking skin.

This anti-aging serum is formulated around Squalane to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Propanediol

Glycerin

Alpha-Arbutin

Dicaprylyl Carbonate

Caprylic/Capric Triglyceride

Phenoxyethanol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Caprylyl Glycol

Squalane

Phospholipids

Glycine Soja Oil

Carbomer

Polysorbate 60

Sodium Phytate

Glycolipids

Sorbitan Isostearate

Leuconostoc/Radish Root Ferment Filtrate

Sodium Hydroxide

Glycine Soja Sterols

Hyaluronic Acid

Tocopherol

Water, Butylene Glycol, Propanediol, Glycerin, Alpha-Arbutin, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Caprylyl Glycol, Squalane, Phospholipids, Glycine Soja Oil, Carbomer, Polysorbate 60, Sodium Phytate, Glycolipids, Sorbitan Isostearate, Leuconostoc/Radish Root Ferment Filtrate, Sodium Hydroxide, Glycine Soja Sterols, Hyaluronic Acid, Tocopherol

Cetearyl Isononanoate

Isononyl Isononanoate

Pentylene Glycol

PPG-3 Myristyl Ether

Ethylene/Propylene/Styrene Copolymer

Dipsacus Sylvestris Extract

Parfum

Tromethamine

Silybum Marianum Seed Oil

Tocopheryl Acetate

Escin

Chenopodium Quinoa Seed Extract

Ethylhexylglycerin

Avena Sativa Kernel Extract

Theobroma Cacao Extract

Butylene/Ethylene/Styrene Copolymer

Leontopodium Alpinum Extract

Xanthan Gum

Persea Gratissima Oil Unsaponifiables

Caramel

Curcuma Longa Root Extract

Salicyloyl Phytosphingosine

Musa Sapientum Fruit Extract

Salicornia Herbacea Extract

Actinidia Chinensis Fruit Extract

Kalanchoe Pinnata Leaf Extract

Sodium Benzoate

Citric Acid

Myrothamnus Flabellifolia Leaf/Stem Extract

Disodium EDTA

Lycium Barbarum Fruit Extract

Maltodextrin

Orthosiphon Stamineus Extract

Hedychium Coronarium Root Extract

Mangifera Indica Leaf Extract

Potassium Sorbate

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Jania Rubens Extract

Ascorbic Acid

Sodium Citrate

Engelhardtia Chrysolepis Leaf Extract

CI 14700

Callicarpa Japonica Fruit Extract

Water, Cetearyl Isononanoate, Glycerin, Isononyl Isononanoate, Caprylic/Capric Triglyceride, Pentylene Glycol, PPG-3 Myristyl Ether, Ethylene/Propylene/Styrene Copolymer, Dipsacus Sylvestris Extract, Butylene Glycol, Parfum, Phenoxyethanol, Propanediol, Tromethamine, Silybum Marianum Seed Oil, Carbomer, Tocopheryl Acetate, Escin, Chenopodium Quinoa Seed Extract, Ethylhexylglycerin, Squalane, Avena Sativa Kernel Extract, Theobroma Cacao Extract, Butylene/Ethylene/Styrene Copolymer, Leontopodium Alpinum Extract, Xanthan Gum, Persea Gratissima Oil Unsaponifiables, Caramel, Curcuma Longa Root Extract, Salicyloyl Phytosphingosine, Musa Sapientum Fruit Extract, Salicornia Herbacea Extract, Actinidia Chinensis Fruit Extract, Kalanchoe Pinnata Leaf Extract, Sodium Benzoate, Citric Acid, Myrothamnus Flabellifolia Leaf/Stem Extract, Disodium EDTA, Tocopherol, Lycium Barbarum Fruit Extract, Maltodextrin, Orthosiphon Stamineus Extract, Hedychium Coronarium Root Extract, Mangifera Indica Leaf Extract, Potassium Sorbate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Jania Rubens Extract, Ascorbic Acid, Sodium Citrate, Engelhardtia Chrysolepis Leaf Extract, CI 14700, Callicarpa Japonica Fruit Extract

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  4. 04Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  5. 05It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  6. 06Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
  7. 07A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
  8. 08Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  9. 09Topically, glycerin does several things at once:
  10. 10Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  11. 11Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  12. 12This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  13. 13Just know very high concentrations (>40%) can feel tacky in low humidity.
  14. 14Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  15. 15Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
  16. 16It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
  17. 17On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
  18. 18Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
  19. 19You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
  20. 20Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Source · skinsort.com
02

Product index

Related product references

Product

The Inkey List PHA Body Water Cream

The Inkey List PHA Body Water Cream The Inkey List PHA Body Water Cream ingredients explained: Aqua (Water/Eau), C15-19 Alkane, Gluconolactone, Polyacrylate Crosspolymer-6, Phenoxyethanol, …

Source: incidecoder.comView reference →

Product

The Inkey List Lactic Acid Serum

The Inkey List Lactic Acid Serum The Inkey List Lactic Acid Serum ingredients explained: Aqua (Water), Lactic Acid, Propanediol, Glycerin, Sodium Hydroxide, PPG-26-Buteth-26, Sodium Hyaluro…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side