Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

The INKEY List Alpha Hydroxy Acid Versus Lancôme Advanced Génifique Youth Activating Concentrate

The INKEY List Alpha Hydroxy Acid Versus Lancôme Advanced Génifique Youth Activating Concentrate This brightening serum is formulated around Ascorbyl Glucoside to brighten dull-looking skin and fade the look of dark spots. This anti-aging serum is formulated a

The INKEY List Alpha Hydroxy Acid Versus Lancôme Advanced Génifique Youth Activating Concentrate

This brightening serum is formulated around Ascorbyl Glucoside to brighten dull-looking skin and fade the look of dark spots.

This anti-aging serum is formulated around Bifida Ferment Lysate and Ascorbyl Glucoside to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Vaccinium Myrtillus Fruit Extract

Glycerin

Saccharum Officinarum Extract

Ascorbyl Glucoside

Sodium Hydroxide

Sodium Hyaluronate 1%

Citrus Aurantium Dulcis Fruit Extract

Citrus Limon Fruit Extract

Xanthan Gum

Acer Saccharum Extract

Sodium Benzoate

Allantoin

Sodium Levulinate

Potassium Sorbate

Sodium Anisate

Trisodium Ethylenediamine Disuccinate

Water, Propanediol, Vaccinium Myrtillus Fruit Extract, Glycerin, Saccharum Officinarum Extract, Ascorbyl Glucoside, Sodium Hydroxide, Sodium Hyaluronate 1%, Citrus Aurantium Dulcis Fruit Extract, Citrus Limon Fruit Extract, Xanthan Gum, Acer Saccharum Extract, Sodium Benzoate, Allantoin, Sodium Levulinate, Potassium Sorbate, Sodium Anisate, Trisodium Ethylenediamine Disuccinate

Bifida Ferment Lysate

Alcohol Denat.

Dimethicone

Hydroxyethylpiperazine Ethane Sulfonic Acid

Sodium Hyaluronate

Phenoxyethanol

Adenosine

Yeast Extract

PEG-20 Methyl Glucose Sesquistearate

PEG-60 Hydrogenated Castor Oil

Salicyloyl Phytosphingosine

Ammonium Polyacryloyldimethyl Taurate

Limonene

Caprylyl Glycol

Disodium EDTA

Octyldodecanol

Citronellol

Parfum

Water, Bifida Ferment Lysate, Glycerin, Alcohol Denat., Dimethicone, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ascorbyl Glucoside, Sodium Hyaluronate, Sodium Hydroxide, Sodium Benzoate, Phenoxyethanol, Adenosine, Yeast Extract, PEG-20 Methyl Glucose Sesquistearate, PEG-60 Hydrogenated Castor Oil, Salicyloyl Phytosphingosine, Ammonium Polyacryloyldimethyl Taurate, Limonene, Xanthan Gum, Caprylyl Glycol, Disodium EDTA, Octyldodecanol, Citronellol, Parfum

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ascorbyl Glucoside (AA-2G) is one of the most stable vitamin C derivatives out there.

It's made by attaching a glucose molecule to ascorbic acid; this glucose "cap" shields the vitamin C from air, light, heat, and metal ions that normally cause pure ascorbic acid to oxidize.

Once on your skin, the enzyme alpha-glucosidase snips off the glucose and gradually releases active ascorbic acid right where it's needed. Basically, it behaves like a slow-release pro-vitamin C with less of a stinging that high-strength ascorbic acid can cause.

The research supports the classic vitamin C benefits as well. In lab and human studies, AA-2G slowed down the skin's production of melanin (the pigment behind dark spots) and helped shield skin cells against sun damage better than ascorbyl phosphate.

These studies also showed AA-2G released vitamin C over a longer period.

A frequently cited manufacturer trial found that a 2% AA-2G face cream significantly improved wrinkle depth and skin roughness after 45 days.

And in 2009, a clinical trial showed it meaningfully lightened dark patches on the gums compared to a placebo.

There's also collagen-synthesis support (since vitamin C is a required cofactor for that) and an antioxidant effect too.

Typical usage is usually between 0.5-5% and most studies/products land around 2%.

AA-2G performs best when formulated at a mildly acidic pH (~5-7) which is much gentler than the pH that pure vitamin C demands (~2.5-3.5).

Just one thing worth knowing: the in-skin conversation rate is only about 55-60% by weight. So a 5% AA-2G product delivers roughly 2.75-3% of actual active vitamin C. On top of that, skin absorption is relatively low because the ingredient is water-soluble.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

The Inkey List Retinol Eye CreamIngredients explained

  1. 01Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
  2. 02It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
  3. 03Expand to read more
  4. 04Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
  5. 05One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
  6. 06A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by ever…
  7. 07A natural moisturizer that’s also in our skin
  8. 08A super common, safe, effective and cheap molecule used for more than 50 years
  9. 09Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  10. 10Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
  11. 11High-glycerin moisturizers are awesome for treating severely dry skin
  12. 12Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
  13. 13BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting…
  14. 14It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
  15. 15We don't have description for this ingredient yet.
  16. 16An "eco-designed" emollient ester coming from shea butter. While pure shea butter is a rich emollient that might feel greasy on the skin, this one is designed for its light, silky-soft feeling.
  17. 17The manufacturer claims that it has a great sustainability profile, long lasting stability and a unique, light and silky feel that's ideal as a base for modern, eco-friendly body lotions and facial care products.
  18. 18An ester that comes from Cetearyl alcohol and the fatty acids of olive oil. It often comes to the formula coupled with Sorbitan Olivate as the two together form the well-known, natural emulsifier trade named Olivem 1000.
  19. 19Other than helping oil and water to blend, the main thing of Olivem 1000 is generating liquid crystal structures that are similar to the lipid structures of the stratum corneum (the outermost layer of the skin). Thanks to this, Olivem 1000 doubles a…
  20. 20It also helps to deliver water-soluble actives such as caffeine more effectively, and can even boost SPF in sunscreen formulas. Its typical use level is 1-5% and has wide compatibility with other actives and oils.
Source · incidecoder.com
02

Product index

Related product references

Product

The Inkey List Caffeine Eye Cream

The Inkey List Caffeine Eye Cream The Inkey List Caffeine Eye Cream ingredients explained: Water, Glycerin, Dicaprylyl Carbonate, Propanediol, Polyglyceryl-6 Distearate, Cetyl Alcohol, Hydr…

Source: incidecoder.comView reference →

Product

The Inkey List Brighten-i Eye Cream

The Inkey List Brighten-i Eye Cream The Inkey List Brighten-i Eye Cream ingredients explained: Water (Aqua/Eau), Dimethicone, Coco-Caprylate/Caprate, Glycerin, Caprylic/Capric Triglyceride,…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side