Skin science article
The INKEY List C-50 Blemish Night Treatment Versus Paula's Choice Omega+ Complex Eye Cream
The INKEY List C-50 Blemish Night Treatment Versus Paula's Choice Omega+ Complex Eye Cream This acne treatment is formulated around Sodium Ascorbyl Phosphate and Salicylic Acid to clear breakouts and refine skin texture. This barrier-repair eye moisturizer is
The INKEY List C-50 Blemish Night Treatment Versus Paula's Choice Omega+ Complex Eye Cream
This acne treatment is formulated around Sodium Ascorbyl Phosphate and Salicylic Acid to clear breakouts and refine skin texture.
This barrier-repair eye moisturizer is formulated around Borago Officinalis Seed Oil and Niacinamide to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propanediol
Sodium Ascorbyl Phosphate
Salicylic Acid
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Phenoxyethanol
Caprylyl/Capryl Glucoside
Xanthan Gum
Glycerin
Sodium Hydroxide
Madecassoside
Ethylhexylglycerin
Hydroxyacetophenone
Sodium Gluconate
Sodium Metabisulfite
Lecithin
Ascorbyl Palmitate
Nelumbo Nucifera Flower Extract
Nymphaea Coerulea Flower Extract
Tocopherol
Helianthus Annuus Seed Oil
Water, Propanediol, Sodium Ascorbyl Phosphate, Salicylic Acid, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Phenoxyethanol, Caprylyl/Capryl Glucoside, Xanthan Gum, Glycerin, Sodium Hydroxide, Madecassoside, Ethylhexylglycerin, Hydroxyacetophenone, Sodium Gluconate, Sodium Metabisulfite, Lecithin, Ascorbyl Palmitate, Nelumbo Nucifera Flower Extract, Nymphaea Coerulea Flower Extract, Tocopherol, Helianthus Annuus Seed Oil
Caprylic/Capric Triglyceride
Butylene Glycol
Neopentyl Glycol Diheptanoate
Cetyl Palmitate
Nylon-12
Propylene Glycol Dibenzoate
Persea Gratissima Oil
Borago Officinalis Seed Oil
Sodium Stearoyl Glutamate
Squalane
Niacinamide
Salvia Hispanica Seed Oil
Linum Usitatissimum Seed Oil
Limnanthes Alba Seed Oil
Olea Europaea Fruit Oil
Passiflora Edulis Seed Oil
Ceramide EOP
Ceramide NP
Ceramide AP
Sodium Hyaluronate
Cholesterol
Morus Alba Root Extract
Arctostaphylos Uva-Ursi Leaf Extract
Glycyrrhiza Glabra Root Extract
Linoleic Acid
Linolenic Acid
Serine
Alanine
Proline
Arginine
Threonine
Phytosphingosine
Phytosterols
Sodium PCA
Glycine
Oleic Acid
Glutamic Acid
Lysine Hcl
Adenosine
Sodium Lactate
Hydrogenated Olive Oil
Euterpe Oleracea Sterols
Olea Europaea Oil Unsaponifiables
Phytic Acid
Scutellaria Baicalensis Root Extract
Anastatica Hierochuntica Extract
PCA
Betaine
Pullulan
Carbomer
Sclerotium Gum
Sodium Citrate
Citric Acid
Tocopheryl Acetate
Silica
Sorbitan Oleate
Sodium Lauroyl Lactylate
Chlorphenesin
Water, Caprylic/Capric Triglyceride, Butylene Glycol, Neopentyl Glycol Diheptanoate, Cetyl Palmitate, Nylon-12, Propanediol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Propylene Glycol Dibenzoate, Persea Gratissima Oil, Borago Officinalis Seed Oil, Sodium Stearoyl Glutamate, Squalane, Niacinamide, Salvia Hispanica Seed Oil, Linum Usitatissimum Seed Oil, Limnanthes Alba Seed Oil, Olea Europaea Fruit Oil, Passiflora Edulis Seed Oil, Ceramide EOP, Ceramide NP, Ceramide AP, Sodium Hyaluronate, Cholesterol, Morus Alba Root Extract, Arctostaphylos Uva-Ursi Leaf Extract, Glycyrrhiza Glabra Root Extract, Linoleic Acid, Linolenic Acid, Serine, Alanine, Proline, Arginine, Threonine, Phytosphingosine, Phytosterols, Sodium PCA, Glycine, Oleic Acid, Glutamic Acid, Lysine Hcl, Lecithin, Adenosine, Sodium Lactate, Hydrogenated Olive Oil, Euterpe Oleracea Sterols, Olea Europaea Oil Unsaponifiables, Phytic Acid, Scutellaria Baicalensis Root Extract, Anastatica Hierochuntica Extract, Glycerin, PCA, Betaine, Pullulan, Carbomer, Sclerotium Gum, Sodium Citrate, Citric Acid, Ascorbyl Palmitate, Tocopheryl Acetate, Silica, Sorbitan Oleate, Xanthan Gum, Sodium Lauroyl Lactylate, Phenoxyethanol, Ethylhexylglycerin, Chlorphenesin
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.
The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:
Due to its large molecular size, it sits on the surface of skin rather than penetrating it.
Ascorbyl Palmitate is a fat-soluble form of vitamin C (Ascorbic Acid) made by combining it with palmitic acid.
It is able to blend easily into creams and oil-based formulas because it dissolves in oils rather than water.
As you may know, regular vitamin C is notorious for breaking down when exposed to sunlight and air. Ascorbyl Palmitate is more stable and degrades at a slower rate.
Research on whether it converts efficiently into active vitamin C once it's applied on your skin is still limited.
Some in-vitro studies suggest it may support collagen production, but it is not considered one of the stronger vitamin C derivatives, like:
Due to the palmitic acid base, this ingredient may not be fungal acne safe. Comedogenic studies have also shown this ingredient to have a rating of 2.
It's also worth keeping in mind that comedogenic and irritancy ratings are tested on individual ingredients, not finished formulas. The final product's formulation, concentration, and other ingredients all play a role in how something actually behaves on your skin.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.