Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

The INKEY List Caffeine Eye Cream Versus Caudalie Resveratrol Lift Firming Eye Gel-Cream

The INKEY List Caffeine Eye Cream Versus Caudalie Resveratrol Lift Firming Eye Gel-Cream This anti-aging eye moisturizer is formulated around Caffeine and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles. This anti-aging eye moisturizer is formulated ar

The INKEY List Caffeine Eye Cream Versus Caudalie Resveratrol Lift Firming Eye Gel-Cream

This anti-aging eye moisturizer is formulated around Caffeine and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.

This anti-aging eye moisturizer is formulated around Palmitoyl Grapevine Shoot Extract and Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-47 to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dicaprylyl Carbonate

Propanediol

Polyglyceryl-6 Distearate

Cetyl Alcohol

Glyceryl Behenate

Phenoxyethanol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Jojoba Esters

Albizia Julibrissin Bark Extract

Squalane

Caffeine

Polyglyceryl-3 Beeswax

Phospholipids

Ethylhexylglycerin

Xanthan Gum

Glycine Soja Oil

Polysorbate 60

Sodium Phytate

Glycolipids

Sorbitan Isostearate

Butylene Glycol

Citric Acid

Glycine Soja Sterols

Leuconostoc/Radish Root Ferment Filtrate

Hyaluronic Acid

Sodium Benzoate

Tocopherol

Carbomer

Darutoside

Sodium Lactate

Polysorbate 20

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Water, Glycerin, Dicaprylyl Carbonate, Propanediol, Polyglyceryl-6 Distearate, Cetyl Alcohol, Glyceryl Behenate, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Jojoba Esters, Albizia Julibrissin Bark Extract, Squalane, Caffeine, Polyglyceryl-3 Beeswax, Phospholipids, Ethylhexylglycerin, Xanthan Gum, Glycine Soja Oil, Polysorbate 60, Sodium Phytate, Glycolipids, Sorbitan Isostearate, Butylene Glycol, Citric Acid, Glycine Soja Sterols, Leuconostoc/Radish Root Ferment Filtrate, Hyaluronic Acid, Sodium Benzoate, Tocopherol, Carbomer, Darutoside, Sodium Lactate, Polysorbate 20, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1

Coco-Caprylate/Caprate

Isoamyl Laurate

Polyacrylate Crosspolymer-6

Sodium Polyacrylate

Palmitoyl Grapevine Shoot Extract

Sclerotium Gum

Chenopodium Quinoa Seed Extract

Helianthus Annuus Seed Oil

Benzyl Alcohol

Hydrolyzed Hyaluronic Acid

Caesalpinia Spinosa Fruit Extract

Adenosine

Acetyl Dipeptide-1 Cetyl Ester

Kappaphycus Alvarezii Extract

Pentylene Glycol

Khaya Senegalensis Bark Extract

Maltodextrin

Paeonia Lactiflora Root Extract

Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-47

Water, Butylene Glycol, Glycerin, Coco-Caprylate/Caprate, Isoamyl Laurate, Polyacrylate Crosspolymer-6, Ethylhexylglycerin, Sodium Polyacrylate, Palmitoyl Grapevine Shoot Extract, Sclerotium Gum, Xanthan Gum, Chenopodium Quinoa Seed Extract, Helianthus Annuus Seed Oil, Tocopherol, Benzyl Alcohol, Hydrolyzed Hyaluronic Acid, Caesalpinia Spinosa Fruit Extract, Adenosine, Acetyl Dipeptide-1 Cetyl Ester, Sodium Phytate, Sodium Benzoate, Kappaphycus Alvarezii Extract, Hyaluronic Acid, Pentylene Glycol, Khaya Senegalensis Bark Extract, Maltodextrin, Paeonia Lactiflora Root Extract, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-47

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.

Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  4. 04Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  5. 05It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  6. 06Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
  7. 07A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
  8. 08Dicaprylyl Carbonate comes from carbonic acid and caprylyl alcohol, a fatty alcohol. It is an emollient and gives skin a velvet feel. The sources of Dicaprylyl Carbonate may be synthetic or from animals.
  9. 09As an emollient, Dicaprylyl Carbonate creates a film on the skin. This film traps moisture in, keeping your skin soft and hydrated.
  10. 10Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  11. 11Topically, glycerin does several things at once:
  12. 12Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  13. 13Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  14. 14This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  15. 15Just know very high concentrations (>40%) can feel tacky in low humidity.
  16. 16Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  17. 17This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
  18. 18It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.
  19. 19Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
  20. 20It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
Source · skinsort.com
02

Product index

Related product references

Product

The Inkey List Fulvic Acid Cleanser

The Inkey List Fulvic Acid Cleanser The Inkey List Fulvic Acid Cleanser ingredients explained: Aqua (Water), Coco-Glucoside, Glycerin, Butylene Glycol, Xanthan Gum, Phenoxyethanol, Benzyl A…

Source: incidecoder.comView reference →

Product

The Inkey List Oat Balm Cleanser

The Inkey List Oat Balm Cleanser The Inkey List Oat Balm Cleanser ingredients explained: Prunus Amygdalus Dulcis (Sweet Almond) Oil, PEG-20 Glyceryl Triisostearate, Avena Sativa (Oat) Kerne…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side