Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

The INKEY List Caffeine Eye Cream Versus Origins GinZing™ Refreshing Eye Cream to Brighten and Depuff

The INKEY List Caffeine Eye Cream Versus Origins GinZing™ Refreshing Eye Cream to Brighten and Depuff This anti-aging eye moisturizer is formulated around Caffeine and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles. This eye moisturizer is formulated

The INKEY List Caffeine Eye Cream Versus Origins GinZing™ Refreshing Eye Cream to Brighten and Depuff

This anti-aging eye moisturizer is formulated around Caffeine and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.

This eye moisturizer is formulated around Panax Ginseng Root Extract and Caffeine to hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dicaprylyl Carbonate

Propanediol

Polyglyceryl-6 Distearate

Cetyl Alcohol

Glyceryl Behenate

Phenoxyethanol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Jojoba Esters

Albizia Julibrissin Bark Extract

Squalane

Caffeine

Polyglyceryl-3 Beeswax

Phospholipids

Ethylhexylglycerin

Xanthan Gum

Glycine Soja Oil

Polysorbate 60

Sodium Phytate

Glycolipids

Sorbitan Isostearate

Butylene Glycol

Citric Acid

Glycine Soja Sterols

Leuconostoc/Radish Root Ferment Filtrate

Hyaluronic Acid

Sodium Benzoate

Tocopherol

Carbomer

Darutoside

Sodium Lactate

Polysorbate 20

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Water, Glycerin, Dicaprylyl Carbonate, Propanediol, Polyglyceryl-6 Distearate, Cetyl Alcohol, Glyceryl Behenate, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Jojoba Esters, Albizia Julibrissin Bark Extract, Squalane, Caffeine, Polyglyceryl-3 Beeswax, Phospholipids, Ethylhexylglycerin, Xanthan Gum, Glycine Soja Oil, Polysorbate 60, Sodium Phytate, Glycolipids, Sorbitan Isostearate, Butylene Glycol, Citric Acid, Glycine Soja Sterols, Leuconostoc/Radish Root Ferment Filtrate, Hyaluronic Acid, Sodium Benzoate, Tocopherol, Carbomer, Darutoside, Sodium Lactate, Polysorbate 20, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1

Methyl Trimethicone

PEG-100 Stearate

Dimethicone

Cetyl Ricinoleate

Silica

Olea Europaea Fruit Oil

Behenyl Alcohol

Cucumis Sativus Fruit Extract

Panax Ginseng Root Extract

Castanea Sativa Seed Extract

Camellia Sinensis Leaf Extract

Cordyceps Sinensis Extract

Magnolia Officinalis Bark Extract

Pyrus Malus Fruit Extract

Scutellaria Baicalensis Root Extract

Pantethine

Panthenol

Caprylic/Capric Triglyceride

Butyrospermum Parkii Butter

Coleus Barbatus Root Extract

Faex Extract

Folic Acid

Hydrogenated Lecithin

Jojoba Wax PEG-120 Esters

Biotin

Tribehenin

Myristyl Alcohol

Trehalose

Sodium Hyaluronate

Ascorbyl Tocopheryl Maleate

Hesperidin Methyl Chalcone

Sodium Sulfite

Sodium Metabisulfite

Steareth-20

Dipeptide-2

Tromethamine

Sorbic Acid

Chlorphenesin

Mica

CI 77891

CI 77491

CI 77492

CI 77499

Water, Methyl Trimethicone, Butylene Glycol, PEG-100 Stearate, Dimethicone, Cetyl Ricinoleate, Silica, Olea Europaea Fruit Oil, Glycerin, Behenyl Alcohol, Cucumis Sativus Fruit Extract, Panax Ginseng Root Extract, Castanea Sativa Seed Extract, Camellia Sinensis Leaf Extract, Cordyceps Sinensis Extract, Magnolia Officinalis Bark Extract, Pyrus Malus Fruit Extract, Scutellaria Baicalensis Root Extract, Pantethine, Panthenol, Caprylic/Capric Triglyceride, Butyrospermum Parkii Butter, Caffeine, Coleus Barbatus Root Extract, Faex Extract, Folic Acid, Hydrogenated Lecithin, Jojoba Wax PEG-120 Esters, Biotin, Tribehenin, Myristyl Alcohol, Palmitoyl Tetrapeptide-7, Trehalose, Sodium Hyaluronate, Ascorbyl Tocopheryl Maleate, Hesperidin Methyl Chalcone, Sodium Sulfite, Sodium Metabisulfite, Steareth-20, Dipeptide-2, Ethylhexylglycerin, Carbomer, Tromethamine, Sorbic Acid, Chlorphenesin, Phenoxyethanol, Mica, CI 77891, CI 77491, CI 77492, CI 77499

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.

As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.

Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.

You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.

Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.

Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".

"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.

This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.

Clinical testing showed statistically significant improvements in:

Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.

You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Ascorbyl Glucoside
  3. 03Sodium Hydroxide
  4. 04PEG-40 Hydrogenated Castor Oil
  5. 05Phenoxyethanol
  6. 06Benzyl Alcohol
  7. 07Butylene Glycol
  8. 08Xanthan Gum
  9. 09Ethylhexylglycerin
  10. 10Sodium Metabisulfite
  11. 11Dehydroacetic Acid
  12. 12Phytic Acid
  13. 13Oligopeptide-1
  14. 14Water, Ascorbyl Glucoside, Sodium Hydroxide, PEG-40 Hydrogenated Castor Oil, Phenoxyethanol, Benzyl Alcohol, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Sodium Metabisulfite, Dehydroacetic Acid, Phytic Acid, Oligopeptide-1
  15. 15Magnesium Ascorbyl Phosphate
  16. 16Propanediol
  17. 17Dimethicone
  18. 18Glyceryl Stearate Se
  19. 19Polyglyceryl-10 Oleate
  20. 20Caprylic/Capric Triglyceride
Source · skinsort.com
02

Product index

Related product references

Product

The Inkey List Fulvic Acid Cleanser

The Inkey List Fulvic Acid Cleanser The Inkey List Fulvic Acid Cleanser ingredients explained: Aqua (Water), Coco-Glucoside, Glycerin, Butylene Glycol, Xanthan Gum, Phenoxyethanol, Benzyl A…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side