Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

The INKEY List Hyaluronic Acid Serum Versus The INKEY List C-50 Blemish Night Treatment

The INKEY List Hyaluronic Acid Serum Versus The INKEY List C-50 Blemish Night Treatment This hydrating serum is formulated around Sodium Hyaluronate and Hyaluronic Acid to hydrate skin and strengthen the skin barrier. This acne treatment is formulated around S

The INKEY List Hyaluronic Acid Serum Versus The INKEY List C-50 Blemish Night Treatment

This hydrating serum is formulated around Sodium Hyaluronate and Hyaluronic Acid to hydrate skin and strengthen the skin barrier.

This acne treatment is formulated around Sodium Ascorbyl Phosphate and Salicylic Acid to clear breakouts and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Sodium Hyaluronate

Glycerin

Butylene Glycol

Phenoxyethanol

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Leuconostoc/Radish Root Ferment Filtrate

Hyaluronic Acid

Carbomer

Sodium Lactate

Polysorbate 20

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Water, Propanediol, Sodium Hyaluronate, Glycerin, Butylene Glycol, Phenoxyethanol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Leuconostoc/Radish Root Ferment Filtrate, Hyaluronic Acid, Carbomer, Sodium Lactate, Polysorbate 20, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1

Sodium Ascorbyl Phosphate

Salicylic Acid

Caprylyl/Capryl Glucoside

Xanthan Gum

Sodium Hydroxide

Madecassoside

Ethylhexylglycerin

Hydroxyacetophenone

Sodium Gluconate

Sodium Metabisulfite

Lecithin

Ascorbyl Palmitate

Nelumbo Nucifera Flower Extract

Nymphaea Coerulea Flower Extract

Tocopherol

Helianthus Annuus Seed Oil

Water, Propanediol, Sodium Ascorbyl Phosphate, Salicylic Acid, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Phenoxyethanol, Caprylyl/Capryl Glucoside, Xanthan Gum, Glycerin, Sodium Hydroxide, Madecassoside, Ethylhexylglycerin, Hydroxyacetophenone, Sodium Gluconate, Sodium Metabisulfite, Lecithin, Ascorbyl Palmitate, Nelumbo Nucifera Flower Extract, Nymphaea Coerulea Flower Extract, Tocopherol, Helianthus Annuus Seed Oil

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.

Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.

The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:

Due to its large molecular size, it sits on the surface of skin rather than penetrating it.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  7. 07Topically, glycerin does several things at once:
  8. 08Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  9. 09Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  10. 10This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  11. 11Just know very high concentrations (>40%) can feel tacky in low humidity.
  12. 12Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  13. 13Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
  14. 14And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
  15. 15You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
  16. 16In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
  17. 17If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
  18. 18When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
  19. 19When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
  20. 20In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Source · skinsort.com
02

Product index

Related product references

Product

The Inkey List Oat Balm Cleanser

The Inkey List Oat Balm Cleanser The Inkey List Oat Balm Cleanser ingredients explained: Prunus Amygdalus Dulcis (Sweet Almond) Oil, PEG-20 Glyceryl Triisostearate, Avena Sativa (Oat) Kerne…

Source: incidecoder.comView reference →

Product

The Inkey List Bakuchiol

The Inkey List Bakuchiol The Inkey List Bakuchiol ingredients explained: Aqua (Water/Eau), Squalane, Glycerin, Propanediol, Plukenetia Volubilis Seed Oil (Sacha Inchi Oil), Dicaprylyl Carbo…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side