Skin science article
The INKEY List Mandelic Acid Treatment Versus Good Molecules Discoloration Correcting Serum
The INKEY List Mandelic Acid Treatment Versus Good Molecules Discoloration Correcting Serum This brightening treatment is formulated around Mandelic Acid and Retinol to fade the look of dark spots and refine skin texture. This brightening serum is formulated a
The INKEY List Mandelic Acid Treatment Versus Good Molecules Discoloration Correcting Serum
This brightening treatment is formulated around Mandelic Acid and Retinol to fade the look of dark spots and refine skin texture.
This brightening serum is formulated around Niacinamide to fade the look of dark spots and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propanediol
Mandelic Acid
Coco-Caprylate/Caprate
Cetearyl Alcohol
Glycerin
Sodium Hydroxide
Caprylic/Capric Triglyceride
Glyceryl Stearate
Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters
Sodium Stearoyl Glutamate
Phenoxyethanol
Sodium Stearoyl Lactylate
Benzyl Alcohol
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Copernicia Cerifera Cera
Retinol
Polysorbate 20
Ethylhexylglycerin
Dehydroacetic Acid
Helianthus Annuus Seed Oil
Trisodium Ethylenediamine Disuccinate
Ceramide AP
1,2-Hexanediol
Caprylyl Glycol
Disodium Cocoamphodiacetate
Tocopherol
Xanthan Gum
Ethyl Ferulate
Humulus Lupulus Extract
Water, Propanediol, Mandelic Acid, Coco-Caprylate/Caprate, Cetearyl Alcohol, Glycerin, Sodium Hydroxide, Caprylic/Capric Triglyceride, Glyceryl Stearate, Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters, Sodium Stearoyl Glutamate, Phenoxyethanol, Sodium Stearoyl Lactylate, Benzyl Alcohol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Copernicia Cerifera Cera, Retinol, Polysorbate 20, Ethylhexylglycerin, Dehydroacetic Acid, Helianthus Annuus Seed Oil, Trisodium Ethylenediamine Disuccinate, Ceramide AP, 1,2-Hexanediol, Caprylyl Glycol, Disodium Cocoamphodiacetate, Tocopherol, Xanthan Gum, Ethyl Ferulate, Humulus Lupulus Extract
Niacinamide
Cetyl Tranexamate Mesylate
Ceratonia Siliqua Gum
Tamarindus Indica Seed Gum
Water, Propanediol, Glycerin, Niacinamide, Cetyl Tranexamate Mesylate, Cetearyl Alcohol, Ceratonia Siliqua Gum, Caprylyl Glycol, Tamarindus Indica Seed Gum, Ethylhexylglycerin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!