The INKEY List Mandelic Acid Treatment Versus Theramid Ceramide Treatment

The INKEY List Mandelic Acid Treatment Versus Theramid Ceramide Treatment

This brightening treatment is formulated around Mandelic Acid and Retinol to fade the look of dark spots and refine skin texture.

This barrier-repair serum is formulated around Ceramide Ng and Ceramide NP to strengthen the skin barrier and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Mandelic Acid

Coco-Caprylate/Caprate

Cetearyl Alcohol

Glycerin

Sodium Hydroxide

Caprylic/Capric Triglyceride

Glyceryl Stearate

Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters

Sodium Stearoyl Glutamate

Phenoxyethanol

Sodium Stearoyl Lactylate

Benzyl Alcohol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Copernicia Cerifera Cera

Retinol

Polysorbate 20

Ethylhexylglycerin

Dehydroacetic Acid

Helianthus Annuus Seed Oil

Trisodium Ethylenediamine Disuccinate

Ceramide AP

1,2-Hexanediol

Caprylyl Glycol

Disodium Cocoamphodiacetate

Tocopherol

Xanthan Gum

Ethyl Ferulate

Humulus Lupulus Extract

Water, Propanediol, Mandelic Acid, Coco-Caprylate/Caprate, Cetearyl Alcohol, Glycerin, Sodium Hydroxide, Caprylic/Capric Triglyceride, Glyceryl Stearate, Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters, Sodium Stearoyl Glutamate, Phenoxyethanol, Sodium Stearoyl Lactylate, Benzyl Alcohol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Copernicia Cerifera Cera, Retinol, Polysorbate 20, Ethylhexylglycerin, Dehydroacetic Acid, Helianthus Annuus Seed Oil, Trisodium Ethylenediamine Disuccinate, Ceramide AP, 1,2-Hexanediol, Caprylyl Glycol, Disodium Cocoamphodiacetate, Tocopherol, Xanthan Gum, Ethyl Ferulate, Humulus Lupulus Extract

Dicaprylyl Carbonate

Undecane

Ceramide Ng

Tridecane

Glycine Soja Seed Extract

Ceramide NP

Ceramide As

Ceramide Ns

Ceramide EOP

Gossypium Herbaceum Callus Culture

Dimethicone

Ectoin

Asiaticoside

Madecassic Acid

Asiatic Acid

Silica

Hydrogenated Lecithin

Sclerotium Gum

Dipropylene Glycol

Lecithin

Dimethicone/Vinyl Dimethicone Crosspolymer

Pullulan

Sucrose Distearate

Cholesterol

Citric Acid

Alcohol

Water, Propanediol, Dicaprylyl Carbonate, Glycerin, Undecane, Ceramide Ng, Tridecane, Glycine Soja Seed Extract, Ceramide NP, Ceramide AP, Ceramide As, Ceramide Ns, Ceramide EOP, Gossypium Herbaceum Callus Culture, Dimethicone, Ectoin, Asiaticoside, Madecassic Acid, Asiatic Acid, Silica, Hydrogenated Lecithin, Xanthan Gum, Sclerotium Gum, Dipropylene Glycol, Lecithin, Dimethicone/Vinyl Dimethicone Crosspolymer, Pullulan, Sucrose Distearate, Glyceryl Stearate, Cholesterol, Tocopherol, Citric Acid, Alcohol, Ethylhexylglycerin, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.

You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.

The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.

Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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