The INKEY List Peptide Moisturizer Versus Cetaphil Moisturizing Cream

The INKEY List Peptide Moisturizer Versus Cetaphil Moisturizing Cream

This barrier-repair moisturizer is formulated around Petrolatum and Panthenol to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Caprylic/Capric Triglyceride

Glycerin

C12-15 Alkyl Benzoate

Cetearyl Alcohol

Glyceryl Stearate Se

Betaine

Butylene Glycol

Phenoxyethanol

Benzyl Alcohol

Carbomer

Butyrospermum Parkii Butter

Sodium Stearoyl Glutamate

Sodium Hydroxide

Ethylhexylglycerin

Sodium Gluconate

Tocopheryl Acetate

Dehydroacetic Acid

Hydrogenated Lecithin

Phenethyl Alcohol

Acetyl Hexapeptide-37

Maltodextrin

Pentapeptide-48

Water, Caprylic/Capric Triglyceride, Glycerin, C12-15 Alkyl Benzoate, Cetearyl Alcohol, Glyceryl Stearate Se, Betaine, Butylene Glycol, Phenoxyethanol, Benzyl Alcohol, Carbomer, Butyrospermum Parkii Butter, Sodium Stearoyl Glutamate, Sodium Hydroxide, Ethylhexylglycerin, Sodium Gluconate, Tocopheryl Acetate, Dehydroacetic Acid, Hydrogenated Lecithin, Phenethyl Alcohol, Acetyl Hexapeptide-37, Maltodextrin, Pentapeptide-48

Petrolatum

Dicaprylyl Ether

Dimethicone

Glyceryl Stearate

Cetyl Alcohol

Helianthus Annuus Seed Oil

PEG-30 Stearate

Panthenol

Niacinamide

Prunus Amygdalus Dulcis Oil

Pantolactone

Dimethiconol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Propylene Glycol

Disodium EDTA

Citric Acid

Water, Glycerin, Petrolatum, Dicaprylyl Ether, Dimethicone, Glyceryl Stearate, Cetyl Alcohol, Helianthus Annuus Seed Oil, PEG-30 Stearate, Panthenol, Niacinamide, Prunus Amygdalus Dulcis Oil, Tocopheryl Acetate, Pantolactone, Dimethiconol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Propylene Glycol, Disodium EDTA, Benzyl Alcohol, Phenoxyethanol, Sodium Hydroxide, Citric Acid

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Benzyl Alcohol is an aromatic alcohol with several roles: it's a preservative, solvent, and mild fragrance component with a floral scent.

This ingredient has been deemed safe for use in cosmetic formulations at concentrations up to 5%, and up to 10% in hair dyes. You'll typically see 0.5-2% in most rinse-off or leave-on products.

As a preservative, it works by disrupting the membrane of microbial proteins. This helps keep bacteria and fungi from growing in your products.

The sensitization picture is actually quite assuring as well:of nearly 71,000 patients patch tested with benzyl alcohol, only 0.21% showed a positive reaction with most of them being weakly positive.

This led researchers to conclude that benzyl alcohol cannot be regarded as a significant contact allergen.

It is worth noting this ingredient is classified as one of the EU's regulated fragrance allergens and restricted to 1% in finished products.

Labels must also declare it in concentrations above 0.001% in leave-on products and 0.01% in rinse-off products.

At concentrations around 5%, localized redness and itching can appear as a direct irritant response and not as a true allergic reaction.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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