Skin science article
The INKEY List Q10 Serum Versus Glow Recipe Guava Vitamin C Dark Spot Treatment Serum
The INKEY List Q10 Serum Versus Glow Recipe Guava Vitamin C Dark Spot Treatment Serum This anti-aging serum is formulated around Squalane and Ubiquinone to soften the look of wrinkles and hydrate skin. This brightening serum is formulated around Tetrahexyldecy
The INKEY List Q10 Serum Versus Glow Recipe Guava Vitamin C Dark Spot Treatment Serum
This anti-aging serum is formulated around Squalane and Ubiquinone to soften the look of wrinkles and hydrate skin.
This brightening serum is formulated around Tetrahexyldecyl Ascorbate and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
Propanediol
Glycerin
Dicaprylyl Carbonate
Caprylic/Capric Triglyceride
Dimethicone
Phenoxyethanol
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Caprylyl Glycol
Squalane
Phospholipids
Lecithin
Glycine Soja Oil
Carbomer
Polysorbate 60
Tocopheryl Acetate
Ubiquinone
Sodium Phytate
Glycolipids
Sorbitan Isostearate
Sodium Hydroxide
Glycine Soja Sterols
Leuconostoc/Radish Root Ferment Filtrate
Hyaluronic Acid
Tocopherol
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate
Water, Butylene Glycol, Propanediol, Glycerin, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Dimethicone, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Caprylyl Glycol, Squalane, Phospholipids, Lecithin, Glycine Soja Oil, Carbomer, Polysorbate 60, Tocopheryl Acetate, Ubiquinone, Sodium Phytate, Glycolipids, Sorbitan Isostearate, Sodium Hydroxide, Glycine Soja Sterols, Leuconostoc/Radish Root Ferment Filtrate, Hyaluronic Acid, Tocopherol, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate
C9-12 Alkane
Psidium Guajava Fruit Extract
Tetrahexyldecyl Ascorbate
Tranexamic Acid
Sodium Polyacryloyldimethyl Taurate
3-O-Ethyl Ascorbic Acid
Ascorbyl Glucoside
Magnesium Ascorbyl Phosphate
Sodium Ascorbyl Phosphate
Psidium Guajava Seed Oil
Sodium Hyaluronate
Ferulic Acid
Tremella Fuciformis Sporocarp Extract
Pyrus Malus Fruit Extract
Musa Sapientum Fruit Extract
Prunus Armeniaca Kernel Extract
Pyrus Communis Fruit Extract
Rubus Idaeus Fruit Extract
Melia Azadirachta Flower Extract
Melia Azadirachta Leaf Extract
Corallina Officinalis Extract
Coccinia Indica Fruit Extract
Hexanoyl Dipeptide-3 Norleucine Acetate
Polyglyceryl-10 Dioleate
1,2-Hexanediol
Hydroxyacetophenone
Sodium Stearoyl Glutamate
Coco-Caprylate/Caprate
Betaine
Polyglyceryl-10 Dipalmitate
Sodium Citrate
Potassium Sorbate
Decyl Glucoside
Lauryl Glucoside
Ethylhexylglycerin
Citric Acid
Xanthan Gum
Water, Propanediol, C9-12 Alkane, Psidium Guajava Fruit Extract, Tetrahexyldecyl Ascorbate, Tranexamic Acid, Sodium Polyacryloyldimethyl Taurate, 3-O-Ethyl Ascorbic Acid, Ascorbyl Glucoside, Magnesium Ascorbyl Phosphate, Sodium Ascorbyl Phosphate, Psidium Guajava Seed Oil, Tocopherol, Tocopheryl Acetate, Sodium Hyaluronate, Ferulic Acid, Tremella Fuciformis Sporocarp Extract, Pyrus Malus Fruit Extract, Musa Sapientum Fruit Extract, Prunus Armeniaca Kernel Extract, Pyrus Communis Fruit Extract, Rubus Idaeus Fruit Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Corallina Officinalis Extract, Coccinia Indica Fruit Extract, Hexanoyl Dipeptide-3 Norleucine Acetate, Polyglyceryl-10 Dioleate, Glycerin, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Caprylyl Glycol, Hydroxyacetophenone, Sodium Stearoyl Glutamate, Coco-Caprylate/Caprate, Betaine, Lecithin, Polyglyceryl-10 Dipalmitate, Sodium Citrate, Sodium Phytate, Potassium Sorbate, Decyl Glucoside, Lauryl Glucoside, Ethylhexylglycerin, Citric Acid, Xanthan Gum, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!