Skin science article
The Ordinary Argireline Solution 10% Versus The Ordinary Multi-Peptide Serum for Hair Density
The Ordinary Argireline Solution 10% Versus The Ordinary Multi-Peptide Serum for Hair Density This anti-aging serum is formulated around Acetyl Hexapeptide-8 to soften the look of wrinkles. What's inside Key Ingredients Benefits Concerns No concerns Ingredient
The Ordinary Argireline Solution 10% Versus The Ordinary Multi-Peptide Serum for Hair Density
This anti-aging serum is formulated around Acetyl Hexapeptide-8 to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Propanediol
Acetyl Hexapeptide-8
Trisodium Ethylenediamine Disuccinate
Gellan Gum
Sodium Chloride
Isoceteth-20
Dimethyl Isosorbide
Potassium Sorbate
Phenoxyethanol
Chlorphenesin
Water, Propanediol, Acetyl Hexapeptide-8, Trisodium Ethylenediamine Disuccinate, Gellan Gum, Sodium Chloride, Isoceteth-20, Dimethyl Isosorbide, Potassium Sorbate, Phenoxyethanol, Chlorphenesin
Butylene Glycol
Glycerin
Caffeine
Biotinoyl Tripeptide-1
Acetyl Tetrapeptide-3
Larix Europaea Wood Extract
Pisum Sativum Extract
Scutellaria Baicalensis Root Extract
Triticum Vulgare Germ Extract
Glycine Soja Germ Extract
Trifolium Pratense Flower Extract
Camellia Sinensis Leaf Extract
Apigenin
Oleanolic Acid
Arginine
Glycine
Calcium Gluconate
Zinc Chloride
Lactic Acid
Gluconolactone
Dextran
Maltodextrin
Hydroxyethylcellulose
Xanthan Gum
Pentylene Glycol
Polysorbate 20
PPG-26-Buteth-26
PEG-40 Hydrogenated Castor Oil
Sodium Metabisulfite
Sodium Benzoate
Water, Propanediol, Butylene Glycol, Glycerin, Caffeine, Biotinoyl Tripeptide-1, Acetyl Tetrapeptide-3, Larix Europaea Wood Extract, Pisum Sativum Extract, Scutellaria Baicalensis Root Extract, Triticum Vulgare Germ Extract, Glycine Soja Germ Extract, Trifolium Pratense Flower Extract, Camellia Sinensis Leaf Extract, Apigenin, Oleanolic Acid, Arginine, Glycine, Calcium Gluconate, Zinc Chloride, Lactic Acid, Gluconolactone, Dextran, Maltodextrin, Hydroxyethylcellulose, Xanthan Gum, Pentylene Glycol, Dimethyl Isosorbide, Polysorbate 20, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Sodium Metabisulfite, Sodium Benzoate, Phenoxyethanol, Chlorphenesin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.
Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.
Chlorphenesin is soluble in both water and glycerin.
Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.
Dimethyl Isosorbide (often shortened to DMI) is a sugar-derived solvent made from sorbitol. It's used to dissolve tricky ingredients and help them mix smoothly into a formula.
Many actives sit as gritty crystals when undissolved, so DMI swoops in to full dissolve them. This helps improve texture, stability, and how evenly an active is distributed.
It does have a penetration-enhancing reputation that is a bit more nuanced than marketing suggests; a cell study on human skin found that 10% DMI didn't significantly boost the permeation of Hydroquinone, Salicylic Acid, or Octadecenedioic Acid compared to controls (though it did improve their solubility in the formula itself).
Typical usage concentrations usually range from 1-10% depending on the formula's needs; this ingredient is also well tolerated at these levels.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Trisodium Ethylenediamine Disuccinate is used to help stabilize a product.
It is a chelating agent, meaning it helps prevent metal ions from binding to other ingredients. This prevents unwanted reactions in products. Metal ions can come into a product via the water ingredient. They are found in trace amounts and are not known to be harmful.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!