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The Originote 2 In 1 Lash & Brow Serum Versus Glad2Glow Berry Peptide Eye Cream

The Originote 2 In 1 Lash & Brow Serum Versus Glad2Glow Berry Peptide Eye Cream This anti-aging eye moisturizer is formulated around Niacinamide and Palmitoyl Pentapeptide-4 to soften the look of wrinkles. What's inside Key Ingredients Benefits Concerns Ingred

The Originote 2 In 1 Lash & Brow Serum Versus Glad2Glow Berry Peptide Eye Cream

This anti-aging eye moisturizer is formulated around Niacinamide and Palmitoyl Pentapeptide-4 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propylene Glycol

Glycerin

Butylene Glycol

Glycereth-26

Hydrolyzed Collagen

Propanediol

1,2-Hexanediol

Hydroxyacetophenone

Sodium Hyaluronate

Hydroxyethylcellulose

Sodium Chloride

PEG-40 Hydrogenated Castor Oil

Xanthan Gum

Hydrolyzed Pea Protein

Ethylhexylglycerin

Tocopherol

Panax Ginseng Root Extract

Biotin

Tripeptide-1

Palmitoyl Pentapeptide-4

Water, Propylene Glycol, Glycerin, Butylene Glycol, Glycereth-26, Hydrolyzed Collagen, Propanediol, 1,2-Hexanediol, Hydroxyacetophenone, Sodium Hyaluronate, Hydroxyethylcellulose, Sodium Chloride, PEG-40 Hydrogenated Castor Oil, Xanthan Gum, Hydrolyzed Pea Protein, Ethylhexylglycerin, Tocopherol, Panax Ginseng Root Extract, Biotin, Tripeptide-1, Palmitoyl Pentapeptide-4

Dimethicone

Methylpropanediol

Coco-Caprylate/Caprate

Maris Aqua

Cyclopentasiloxane

Cetyl Alcohol

Octyldodecanol

Glyceryl Stearate

Niacinamide

Cyclohexasiloxane

Methyl Hydrogenated Rosinate

Ammonium Acryloyldimethyltaurate/Vp Copolymer

PEG-75 Stearate

Tocopheryl Acetate

Steareth-20

Ceteth-20

Bisabolol

Pentylene Glycol

Lactobacillus/Soymilk Ferment Filtrate

Gentiana Scabra Root Extract

Hydroxyphenyl Propamidobenzoic Acid

Caffeine

Ceramide EOP

Ceramide AP

Ceramide Ns

Ceramide Ng

Ceramide As

Acetyl Tetrapeptide-5

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Chondrus Crispus Extract

Smithsonite Extract

Peumus Boldus Leaf Extract

Moringa Oleifera Seed Extract

Zea Mays Kernel Extract

Palmaria Palmata Extract

Phytosteryl/Octyldodecyl Lauroyl Glutamate

Ceramide NP

Echinacea Purpurea Extract

Ascorbyl Palmitate

Lycium Barbarum Fruit Extract

Trehalose

Sophora Flavescens Root Extract

Aloe Barbadensis Leaf Extract

Hydrogenated Lecithin

Dendrobium Nobile Stem Extract

Erythritol

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Disodium EDTA

Cyclodextrin

Polysorbate 20

Carbomer

Arginine

Water, Glycerin, Dimethicone, Methylpropanediol, Coco-Caprylate/Caprate, Maris Aqua, Cyclopentasiloxane, Cetyl Alcohol, Octyldodecanol, Glyceryl Stearate, Niacinamide, Cyclohexasiloxane, Hydroxyacetophenone, 1,2-Hexanediol, Methyl Hydrogenated Rosinate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, PEG-75 Stearate, Tocopheryl Acetate, Steareth-20, Ceteth-20, Butylene Glycol, Bisabolol, Pentylene Glycol, Lactobacillus/Soymilk Ferment Filtrate, Gentiana Scabra Root Extract, Hydroxyphenyl Propamidobenzoic Acid, Caffeine, Sodium Hyaluronate, Palmitoyl Pentapeptide-4, Tocopherol, Ceramide EOP, Ceramide AP, Ceramide Ns, Ceramide Ng, Ceramide As, Acetyl Tetrapeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Chondrus Crispus Extract, Smithsonite Extract, Peumus Boldus Leaf Extract, Moringa Oleifera Seed Extract, Zea Mays Kernel Extract, Palmaria Palmata Extract, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Ceramide NP, Echinacea Purpurea Extract, Ascorbyl Palmitate, Lycium Barbarum Fruit Extract, Trehalose, Sophora Flavescens Root Extract, Aloe Barbadensis Leaf Extract, Hydrogenated Lecithin, Dendrobium Nobile Stem Extract, Erythritol, Xanthan Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Disodium EDTA, Cyclodextrin, Polysorbate 20, Carbomer, Arginine

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.

As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.

Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.

This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.

You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.

Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.

An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.

So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.

Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.

You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.

As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.

A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.

The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.

The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.

Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.

Read more about other common types of peptides here:

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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Comparison edit

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