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Skin science article

Theramid Copper Peptide Versus Allies of Skin Peptide & Antioxidants Firming Daily Treatment

Theramid Copper Peptide Versus Allies of Skin Peptide & Antioxidants Firming Daily Treatment This anti-aging serum is formulated around Copper Tripeptide-1 and Bifida Ferment Lysate to soften the look of wrinkles and strengthen the skin barrier. This anti-agin

Theramid Copper Peptide Versus Allies of Skin Peptide & Antioxidants Firming Daily Treatment

This anti-aging serum is formulated around Copper Tripeptide-1 and Bifida Ferment Lysate to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging moisturizer is formulated around Niacinamide and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Dimethicone

Hydrogenated Ethylhexyl Olivate

Betaine

Isododecane

PEG-10 Dimethicone

Copper Tripeptide-1

Bifida Ferment Lysate

Glycerin

PEG/PPG-18/18 Dimethicone

Magnesium Sulfate

Hydrogenated Castor Oil/Sebacic Acid Copolymer

Sodium Hyaluronate

Acetyl Hexapeptide-1

Acetyl Tetrapeptide-2

Trifluoroacetyl Tripeptide-2

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-9

Sh-Polypeptide-11

Bacillus/Folic Acid Ferment Filtrate Extract

Acetyl Glutamine

Disteardimonium Hectorite

Hydrogenated Olive Oil Unsaponifiables

Propylene Carbonate

Lecithin

Caprylyl Glycol

Butylene Glycol

Dextran

Tocopherol

Acetic Acid

Lactic Acid

Disodium EDTA

Sodium Benzoate

1,2-Hexanediol

Ethylhexylglycerin

Phenoxyethanol

Water, Propanediol, Dimethicone, Hydrogenated Ethylhexyl Olivate, Betaine, Isododecane, PEG-10 Dimethicone, Copper Tripeptide-1, Bifida Ferment Lysate, Glycerin, PEG/PPG-18/18 Dimethicone, Magnesium Sulfate, Hydrogenated Castor Oil/Sebacic Acid Copolymer, Sodium Hyaluronate, Acetyl Hexapeptide-1, Acetyl Tetrapeptide-2, Trifluoroacetyl Tripeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Bacillus/Folic Acid Ferment Filtrate Extract, Acetyl Glutamine, Disteardimonium Hectorite, Hydrogenated Olive Oil Unsaponifiables, Propylene Carbonate, Lecithin, Caprylyl Glycol, Butylene Glycol, Dextran, Tocopherol, Acetic Acid, Lactic Acid, Disodium EDTA, Sodium Benzoate, 1,2-Hexanediol, Ethylhexylglycerin, Phenoxyethanol

Caprylic/Capric Triglyceride

Isononyl Isononanoate

Caffeine

C12-15 Alkyl Benzoate

Niacinamide

Lactobacillus Ferment

Cetearyl Olivate

Polysorbate 60

Tetrahexyldecyl Ascorbate

Marrubium Vulgare Extract

Plantago Lanceolata Leaf Extract

Palmitoyl Tripeptide-5

Acetyl Tetrapeptide-40

Palmitoyl Tripeptide-8

Hydrolyzed Verbascum Thapsus Flower

Moringa Oleifera Seed Extract

Teprenone

Phospholipids

Hyaluronic Acid

Syringa Vulgaris Leaf Cell Culture Extract

Sphingolipids

Astaxanthin

Bisabolol

Euterpe Oleracea Fruit Oil

Rubus Idaeus Seed Oil

Honey

Dimethyl Isosorbide

Ceramide NP

Phenyl T-Butylnitrone

Glutathione

Tetrahydrodiferuloylmethane

Tetrahydrodemethoxydiferuloylmethane

Tetrahydrobisdemethoxydiferuloylmethane

Ergothioneine

Xanthan Gum

Carbomer

Sorbitan Olivate

Benzimidazole Diamond Amidoethyl Urea Carbamoyl Propyl Polymethylsilsesquioxane

Mica

Citric Acid

Sodium Hydroxide

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

CI 77891

Isohexadecane

Maltodextrin

Polysorbate 80

Acetyl Tributyl Citrate

Tetrasodium EDTA

Sorbitan Oleate

Potassium Sorbate

Sodium Glycolate

Polysorbate 20

O-Cymen-5-Ol

Water, Glycerin, Caprylic/Capric Triglyceride, Isononyl Isononanoate, Caffeine, C12-15 Alkyl Benzoate, Niacinamide, Lactobacillus Ferment, Cetearyl Olivate, Butylene Glycol, Polysorbate 60, Tetrahexyldecyl Ascorbate, Marrubium Vulgare Extract, Plantago Lanceolata Leaf Extract, Palmitoyl Tripeptide-5, Acetyl Tetrapeptide-40, Palmitoyl Tripeptide-8, Hydrolyzed Verbascum Thapsus Flower, Moringa Oleifera Seed Extract, Teprenone, Phospholipids, Hyaluronic Acid, Syringa Vulgaris Leaf Cell Culture Extract, Sphingolipids, Astaxanthin, Bisabolol, Euterpe Oleracea Fruit Oil, Rubus Idaeus Seed Oil, Honey, Dimethyl Isosorbide, Ceramide NP, Phenyl T-Butylnitrone, Tocopherol, Glutathione, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Ergothioneine, Xanthan Gum, Caprylyl Glycol, Carbomer, Sorbitan Olivate, Benzimidazole Diamond Amidoethyl Urea Carbamoyl Propyl Polymethylsilsesquioxane, Mica, Dextran, Citric Acid, Sodium Hydroxide, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, CI 77891, Ethylhexylglycerin, Isohexadecane, Maltodextrin, Polysorbate 80, Acetyl Tributyl Citrate, Tetrasodium EDTA, Sorbitan Oleate, Sodium Benzoate, Potassium Sorbate, Sodium Glycolate, Polysorbate 20, Phenoxyethanol, O-Cymen-5-Ol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Dextran is a sugar (polysaccharide) with skin hydrating properties.

Fun fact: Louis Pasteur first discovered this ingredient as a microbial product in wine.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
  7. 07The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure …
  8. 08Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
  9. 09Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  10. 10Topically, glycerin does several things at once:
  11. 11Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  12. 12Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  13. 13This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  14. 14Just know very high concentrations (>40%) can feel tacky in low humidity.
  15. 15Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  16. 16Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
  17. 17It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
  18. 18On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
  19. 19Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
  20. 20You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

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