Timeless Skin Care CoEnzyme Q10 Serum Versus Paula's Choice Resist Ultra-Light Super Antioxidant Concentrate Serum

Timeless Skin Care CoEnzyme Q10 Serum Versus Paula's Choice Resist Ultra-Light Super Antioxidant Concentrate Serum

This anti-aging serum is formulated around Matrixyl 3000 and Ubiquinone to soften the look of wrinkles and hydrate skin.

This anti-aging serum is formulated around Resveratrol and Niacinamide to soften the look of wrinkles and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Matrixyl 3000

Ubiquinone

Aloe Barbadensis Leaf Extract

Glycerin

Hyaluronic Acid

Tocopherol

Benzyl Alcohol

Dehydroacetic Acid

Water, Matrixyl 3000, Ubiquinone, Aloe Barbadensis Leaf Extract, Glycerin, Hyaluronic Acid, Tocopherol, Benzyl Alcohol, Dehydroacetic Acid

Cyclopentasiloxane

Butylene Glycol

Dimethicone

Polysorbate 20

Polysilicone-11

Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone

Resveratrol

Niacinamide

Quercetin

Adenosine

Tetrahexyldecyl Ascorbate

Phospholipids

Epigallocatechin Gallate

Sea Whip Extract

Bisabolol

Beta-Glucan

Phytic Acid

Xanthan Gum

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sodium Hydroxide

Disodium EDTA

Ethylhexylglycerin

Phenoxyethanol

Water, Cyclopentasiloxane, Butylene Glycol, Dimethicone, Glycerin, Polysorbate 20, Polysilicone-11, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Hyaluronic Acid, Resveratrol, Niacinamide, Quercetin, Adenosine, Tetrahexyldecyl Ascorbate, Tocopherol, Phospholipids, Ubiquinone, Epigallocatechin Gallate, Sea Whip Extract, Bisabolol, Beta-Glucan, Phytic Acid, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Ubiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.

Aging and environmental exposure diminishes our skin's natural ubiquinone levels. This is much like our natural collagen and elastin.

The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:

Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.

When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.

Fun fact: ubiquinone is fat-soluble.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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