Skin science article
Tree of Life Anti-Aging Ultimate Daytime Glow Facial Serum Versus The INKEY List Retinol Serum
Tree of Life Anti-Aging Ultimate Daytime Glow Facial Serum Versus The INKEY List Retinol Serum This anti-aging serum is formulated around Sodium Ascorbyl Phosphate and Alpha-Arbutin to soften the look of wrinkles and brighten dull-looking skin. This anti-aging
Tree of Life Anti-Aging Ultimate Daytime Glow Facial Serum Versus The INKEY List Retinol Serum
This anti-aging serum is formulated around Sodium Ascorbyl Phosphate and Alpha-Arbutin to soften the look of wrinkles and brighten dull-looking skin.
This anti-aging serum is formulated around Retinyl Acetate and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Santalum Austrocaledonicum Wood Water
Aloe Barbadensis Leaf Juice
Helianthus Annuus Seed Oil
Glycerin
Ethylhexyl Palmitate
Glyceryl Stearate
Tanacetum Annuum Flower Oil
Cocos Nucifera Oil
Simmondsia Chinensis Seed Oil
Theobroma Cacao Seed Butter
Beeswax
Sodium Ascorbyl Phosphate
Panthenol
Alpha-Arbutin
Niacinamide
Ubiquinone
Astaxanthin
Undaria Pinnatifida Cell Culture Extract
Caesalpinia Spinosa Gum
Hydrolyzed Caesalpinia Spinosa Gum
Curcuma Longa Rhizome Extract
Hydrangea Arborescens Root Extract
Glycyrrhiza Glabra Root Extract
Prunus Virginiana Bark Extract
Cetyl Alcohol
Potassium Stearate
Alcohol
Phenoxyethanol
Ethylhexylglycerin
Water, Santalum Austrocaledonicum Wood Water, Aloe Barbadensis Leaf Juice, Helianthus Annuus Seed Oil, Glycerin, Ethylhexyl Palmitate, Glyceryl Stearate, Tanacetum Annuum Flower Oil, Cocos Nucifera Oil, Simmondsia Chinensis Seed Oil, Theobroma Cacao Seed Butter, Beeswax, Sodium Ascorbyl Phosphate, Panthenol, Alpha-Arbutin, Niacinamide, Ubiquinone, Astaxanthin, Undaria Pinnatifida Cell Culture Extract, Caesalpinia Spinosa Gum, Hydrolyzed Caesalpinia Spinosa Gum, Curcuma Longa Rhizome Extract, Hydrangea Arborescens Root Extract, Glycyrrhiza Glabra Root Extract, Prunus Virginiana Bark Extract, Cetyl Alcohol, Potassium Stearate, Alcohol, Phenoxyethanol, Ethylhexylglycerin
Butylene Glycol
Propanediol
Dicaprylyl Carbonate
Retinyl Acetate
Dimethicone
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Caprylyl Glycol
Phospholipids
Squalane
Glycine Soja Oil
Carbomer
Polysorbate 60
Tocopheryl Acetate
Glycolipids
Sodium Hydroxide
Sodium Phytate
Sorbitan Isostearate
Glycine Soja Sterols
Tetrahexyldecyl Ascorbate
Leuconostoc/Radish Root Ferment Filtrate
Hyaluronic Acid
Sodium Lactate
Tocopherol
Polysorbate 20
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Water, Glycerin, Butylene Glycol, Propanediol, Dicaprylyl Carbonate, Retinyl Acetate, Dimethicone, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Caprylyl Glycol, Phospholipids, Squalane, Glycine Soja Oil, Carbomer, Polysorbate 60, Tocopheryl Acetate, Glycolipids, Sodium Hydroxide, Sodium Phytate, Sorbitan Isostearate, Glycine Soja Sterols, Tetrahexyldecyl Ascorbate, Leuconostoc/Radish Root Ferment Filtrate, Hyaluronic Acid, Sodium Lactate, Tocopherol, Polysorbate 20, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!