Skin science article
Vichy Liftactiv Peptide-C Ampoule Serum Versus Dear, Klairs Freshly Juiced Vitamin Drop
Vichy Liftactiv Peptide-C Ampoule Serum Versus Dear, Klairs Freshly Juiced Vitamin Drop This anti-aging ampoule is formulated around Ascorbic Acid to soften the look of wrinkles and brighten dull-looking skin. This brightening serum is formulated around Ascorb
Vichy Liftactiv Peptide-C Ampoule Serum Versus Dear, Klairs Freshly Juiced Vitamin Drop
This anti-aging ampoule is formulated around Ascorbic Acid to soften the look of wrinkles and brighten dull-looking skin.
This brightening serum is formulated around Ascorbic Acid and Centella Asiatica Extract to brighten dull-looking skin and fade the look of dark spots.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Ascorbic Acid
Butylene Glycol
Dipropylene Glycol
Glycerin
Sodium Hyaluronate
Hydrolyzed Rice Protein
Hydrolyzed Hyaluronic Acid
Hydrolyzed Lupine Protein
Ceramide AP
Water, Ascorbic Acid, Butylene Glycol, Dipropylene Glycol, Glycerin, Sodium Hyaluronate, Hydrolyzed Rice Protein, Hydrolyzed Hyaluronic Acid, Hydrolyzed Lupine Protein, Ceramide AP
Propylene Glycol
Hydroxyethylcellulose
Citrus Junos Fruit Extract
Centella Asiatica Extract
Polysorbate 60
Illicium Verum Fruit Extract
Chaenomeles Sinensis Fruit Extract
Paeonia Suffruticosa Root Extract
Brassica Oleracea Italica Extract
Nelumbium Speciosum Flower Extract
Citrus Paradisi Fruit Extract
Scutellaria Baicalensis Root Extract
Citrus Aurantium Dulcis Oil
1,2-Hexanediol
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Isohexadecane
Disodium EDTA
Lavandula Angustifolia Oil
Camellia Sinensis Callus Culture Extract
Polysorbate 80
Disodium Phosphate
Sorbitan Oleate
Chrysanthellum Indicum Extract
Asarum Sieboldii Root Extract
Quercus Mongolica Leaf Extract
Persicaria Hydropiper Extract
Larix Europaea Wood Extract
Magnolia Obovata Bark Extract
Rheum Palmatum Root Extract
Corydalis Turtschaninovii Root Extract
Coptis Chinensis Root Extract
Sodium Phosphate
Lysine Hcl
Sodium Ascorbyl Phosphate
Acetyl Methionine
Theanine
Proline
Lecithin
Acetyl Glutamine
Bacillus/Folic Acid/Soybean Ferment Extract
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Sh-Polypeptide-11
Sh-Polypeptide-9
Caprylyl Glycol
Limonene
Water, Propylene Glycol, Ascorbic Acid, Hydroxyethylcellulose, Citrus Junos Fruit Extract, Centella Asiatica Extract, Polysorbate 60, Illicium Verum Fruit Extract, Chaenomeles Sinensis Fruit Extract, Paeonia Suffruticosa Root Extract, Brassica Oleracea Italica Extract, Nelumbium Speciosum Flower Extract, Citrus Paradisi Fruit Extract, Scutellaria Baicalensis Root Extract, Butylene Glycol, Glycerin, Citrus Aurantium Dulcis Oil, 1,2-Hexanediol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Disodium EDTA, Lavandula Angustifolia Oil, Camellia Sinensis Callus Culture Extract, Polysorbate 80, Disodium Phosphate, Sorbitan Oleate, Chrysanthellum Indicum Extract, Asarum Sieboldii Root Extract, Quercus Mongolica Leaf Extract, Persicaria Hydropiper Extract, Larix Europaea Wood Extract, Magnolia Obovata Bark Extract, Rheum Palmatum Root Extract, Corydalis Turtschaninovii Root Extract, Coptis Chinensis Root Extract, Sodium Phosphate, Lysine Hcl, Sodium Ascorbyl Phosphate, Acetyl Methionine, Theanine, Proline, Lecithin, Acetyl Glutamine, Bacillus/Folic Acid/Soybean Ferment Extract, Sodium Hyaluronate, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Caprylyl Glycol, Limonene
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ascorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin.
Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for:
Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.
One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.
While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.
The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption.
Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.
Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day.
Read more about other types of Vitamin C:
Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!