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Vichy Liftactiv Peptide-C Ampoule Serum Versus La Roche-Posay Retinol B3 Serum

Vichy Liftactiv Peptide-C Ampoule Serum Versus La Roche-Posay Retinol B3 Serum This anti-aging ampoule is formulated around Ascorbic Acid to soften the look of wrinkles and brighten dull-looking skin. This anti-aging serum is formulated around Niacinamide and

By Peptide Skincare & Beauty Editorial TeamPublished

Vichy Liftactiv Peptide-C Ampoule Serum Versus La Roche-Posay Retinol B3 Serum

This anti-aging ampoule is formulated around Ascorbic Acid to soften the look of wrinkles and brighten dull-looking skin.

This anti-aging serum is formulated around Niacinamide and Retinol to soften the look of wrinkles and fade the look of dark spots.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Ascorbic Acid

Butylene Glycol

Dipropylene Glycol

Glycerin

Sodium Hyaluronate

Hydrolyzed Rice Protein

Hydrolyzed Hyaluronic Acid

Hydrolyzed Lupine Protein

Ceramide AP

Water, Ascorbic Acid, Butylene Glycol, Dipropylene Glycol, Glycerin, Sodium Hyaluronate, Hydrolyzed Rice Protein, Hydrolyzed Hyaluronic Acid, Hydrolyzed Lupine Protein, Ceramide AP

Cyclohexasiloxane

Alcohol Denat.

Pentylene Glycol

Niacinamide

Dimethicone

Glycine Soja Oil

PPG-6-Decyltetradeceth-30

Retinol

Adenosine

Ammonium Polyacryloyldimethyl Taurate

Caprylyl Glycol

Citric Acid

Trisodium Ethylenediamine Disuccinate

Xanthan Gum

Polysilicone-11

Retinyl Palmitate

Tocopherol

Phenoxyethanol

Parfum

Water, Glycerin, Cyclohexasiloxane, Alcohol Denat., Pentylene Glycol, Niacinamide, Dimethicone, Glycine Soja Oil, PPG-6-Decyltetradeceth-30, Sodium Hyaluronate, Retinol, Adenosine, Ammonium Polyacryloyldimethyl Taurate, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Polysilicone-11, Retinyl Palmitate, Tocopherol, Phenoxyethanol, Parfum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Ascorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin.
  4. 04Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for:
  5. 05Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.
  6. 06One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.
  7. 07While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.
  8. 08The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% be…
  9. 09Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.
  10. 10Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at…
  11. 11Read more about other types of Vitamin C:
  12. 12Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.
  13. 13Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  14. 14Topically, glycerin does several things at once:
  15. 15Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  16. 16Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  17. 17This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  18. 18Just know very high concentrations (>40%) can feel tacky in low humidity.
  19. 19Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  20. 20Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Source · skinsort.com ⟶
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