Skin science article
YENSA Pink Lotus Peptide Renewal Face Cream Versus IT Cosmetics Confidence in a Gel Cream Oil-Free Moisturizer
YENSA Pink Lotus Peptide Renewal Face Cream Versus IT Cosmetics Confidence in a Gel Cream Oil-Free Moisturizer This anti-aging moisturizer is formulated around Niacinamide and Adenosine to soften the look of wrinkles and strengthen the skin barrier. This oil-c
YENSA Pink Lotus Peptide Renewal Face Cream Versus IT Cosmetics Confidence in a Gel Cream Oil-Free Moisturizer
This anti-aging moisturizer is formulated around Niacinamide and Adenosine to soften the look of wrinkles and strengthen the skin barrier.
This oil-control moisturizer is formulated around Niacinamide and Gluconolactone to balance excess oil.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Propanediol
Hydrogenated Polydecene
Neopentyl Glycol Dicaprate
Cyclopentasiloxane
Cannabis Sativa Seed Oil
Caprylic/Capric Triglyceride
Cetearyl Alcohol
Dimethicone
Behenyl Alcohol
Butyrospermum Parkii Butter
Niacinamide
Glyceryl Stearate
PEG-100 Stearate
Palmitic Acid
Phenoxyethanol
Stearic Acid
Carbomer
Arginine
Citrus Aurantium Bergamia Fruit Oil
Hydrogenated Lecithin
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Ethylhexylglycerin
Adenosine
Butylene Glycol
Xanthan Gum
Paeonia Lactiflora Extract
Myristic Acid
Malpighia Punicifolia Fruit Extract
Prunus Avium Fruit Extract
Prunus Serrulata Flower Extract
Punica Granatum Fruit Extract
Pyrus Malus Fruit Extract
Citrus Paradisi Fruit Extract
1,2-Hexanediol
Rosa Centifolia Flower Extract
Rubus Idaeus Fruit Extract
Nelumbo Nucifera Flower Extract
Wine Extract
Camellia Japonica Flower Extract
Tocopherol
Acetyl Hexapeptide-8
Linalool
Limonene
Water, Glycerin, Propanediol, Hydrogenated Polydecene, Neopentyl Glycol Dicaprate, Cyclopentasiloxane, Cannabis Sativa Seed Oil, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Dimethicone, Behenyl Alcohol, Butyrospermum Parkii Butter, Niacinamide, Glyceryl Stearate, PEG-100 Stearate, Palmitic Acid, Phenoxyethanol, Stearic Acid, Carbomer, Arginine, Citrus Aurantium Bergamia Fruit Oil, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Ethylhexylglycerin, Adenosine, Butylene Glycol, Xanthan Gum, Paeonia Lactiflora Extract, Myristic Acid, Malpighia Punicifolia Fruit Extract, Prunus Avium Fruit Extract, Prunus Serrulata Flower Extract, Punica Granatum Fruit Extract, Pyrus Malus Fruit Extract, Citrus Paradisi Fruit Extract, 1,2-Hexanediol, Rosa Centifolia Flower Extract, Rubus Idaeus Fruit Extract, Nelumbo Nucifera Flower Extract, Wine Extract, Camellia Japonica Flower Extract, Tocopherol, Acetyl Hexapeptide-8, Linalool, Limonene
Alcohol Denat.
Betaine
Coco-Caprylate/Caprate
Squalane
Hydroxyethylpiperazine Ethane Sulfonic Acid
Aloe Barbadensis Leaf Juice Powder
Sarcosine
Gluconolactone
Menthoxypropanediol
Methyldihydrojasmonate
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Sodium Hydroxide
Tetrasodium Glutamate Diacetate
Zinc PCA
Silica Silylate
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Aluminum Starch Octenylsuccinate
Cetearyl Glucoside
Polysorbate 20
Sodium Lactate
Stearyl Dimethicone
CI 42090
Chlorphenesin
Parfum
Water, Glycerin, Butylene Glycol, Niacinamide, Dimethicone, Alcohol Denat., Betaine, Coco-Caprylate/Caprate, Squalane, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Hydroxyethylpiperazine Ethane Sulfonic Acid, Aloe Barbadensis Leaf Juice Powder, Sarcosine, Adenosine, Gluconolactone, Menthoxypropanediol, Methyldihydrojasmonate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tetrasodium Glutamate Diacetate, Zinc PCA, Hydrogenated Lecithin, Silica Silylate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aluminum Starch Octenylsuccinate, Carbomer, Cetearyl Alcohol, Cetearyl Glucoside, Polysorbate 20, Sodium Lactate, Stearyl Dimethicone, Limonene, Linalool, CI 42090, Chlorphenesin, Phenoxyethanol, Parfum
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.
The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:
Due to its large molecular size, it sits on the surface of skin rather than penetrating it.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Limonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Linalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.
Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.
This ingredient has a scent that is floral, spicy tropical, and citrus-like.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!