Peptide Skincare & BeautySkin science and ingredient guides

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Acure Radically Rejuvenating Whipped Night Cream Versus DRMTLGY Peptide Night Cream

Acure Radically Rejuvenating Whipped Night Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of Acure Radically Rejuvenating Whipped Night Cream versus DRMTLGY Peptide Night Cream. This anti-aging night moisturizer is formulated around Sclerocarya B

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Acure Radically Rejuvenating Whipped Night Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of Acure Radically Rejuvenating Whipped Night Cream versus DRMTLGY Peptide Night Cream. This anti-aging night moisturizer is formulated around Sclerocarya Birrea Seed Oil and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate skin. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. Water Glycerin Cetearyl Alcohol Cetearyl Olivate Sclerocarya Birrea Seed Oil Coconut Alkanes Sorbitan Olivate Ascorbyl Glucoside Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Sh-Polypeptide-1 Sh-Polypeptide-9 Sh-Polypeptide-11 Sh-Oligopeptide-1 Sh-Oligopeptide-2 Acetyl Glutamine Copper Palmitoyl Heptapeptide-14 Heptapeptide-15 Palmitate Pseudoalteromonas Ferment Extract Ferulic Acid Nymphaea Odorata Root Extract Symphytum Officinale Root Cell Extract Sodium PCA Salicylic Acid Sodium Hyaluronate Lecithin Isomalt Linoleic Acid Linolenic Acid Sodium Anisate Xanthan Gum Bacillus/Folic Acid Ferment Filtrate Extract Sodium Levulinate Caprylyl Glycol Coco-Caprylate/Caprate Glyceryl Caprylate Lactic Acid/Glycolic Acid Copolymer Sorbitan Isostearate Carbomer Polysorbate 20 Butylene Glycol Propanediol 1,2-Hexanediol Polyvinyl Alcohol Citric Acid Water, Glycerin, Cetearyl Alcohol, Cetearyl Olivate, Sclerocarya Birrea Seed Oil, Coconut Alkanes, Sorbitan Olivate, Ascorbyl Glucoside, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Acetyl Glutamine, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Pseudoalteromonas Ferment Extract, Ferulic Acid, Nymphaea Odorata Root Extract, Symphytum Officinale Root Cell Extract, Sodium PCA, Salicylic Acid, Sodium Hyaluronate, Lecithin, Isomalt, Linoleic Acid, Linolenic Acid, Sodium Anisate, Xanthan Gum, Bacillus/Folic Acid Ferment Filtrate Extract, Sodium Levulinate, Caprylyl Glycol, Coco-Caprylate/Caprate, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Sorbitan Isostearate, Carbomer, Polysorbate 20, Butylene Glycol, Propanediol, 1,2-Hexanediol, Polyvinyl Alcohol, Citric Acid Glyceryl Stearate C12-15 Alkyl Benzoate Isopropyl Palmitate Undecane Butyrospermum Parkii Butter Caprylic/Capric Triglyceride Cetyl Alcohol Dimethicone PEG-100 Stearate Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Palmitoyl Tripeptide-5 Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Ceramide NP Ceramide AP Ceramide EOP Phytosphingosine Cholesterol Tridecane Allantoin Tocopherol Glycol Distearate Potassium Cetyl Phosphate Ethylhexylglycerin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Dextran Magnesium Chloride Phenoxyethanol Disodium EDTA Sodium Hydroxide Sodium Lauroyl Lactylate Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Trifluoroacetyl Tripeptide-2, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Tridecane, Allantoin, Tocopherol, Glycol Distearate, Potassium Cetyl Phosphate, Butylene Glycol, Ethylhexylgl Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging". "Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age. This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin. Clinical testing showed statistically significant improvements in: Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid. You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects. A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation result