Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Aestura Atobarrier 365 Cream Versus Drunk Elephant Protini Polypeptide Cream

Aestura Atobarrier 365 Cream Versus Drunk Elephant Protini Polypeptide Cream Detailed comparison of Aestura Atobarrier 365 Cream versus Drunk Elephant Protini Polypeptide Cream. This barrier-repair moisturizer is formulated around Squalane and Hydroxypropyl Bi

This source-based comparison does not add ratings or recommend a winner.

Aestura Atobarrier 365 Cream Versus Drunk Elephant Protini Polypeptide Cream Detailed comparison of Aestura Atobarrier 365 Cream versus Drunk Elephant Protini Polypeptide Cream. This barrier-repair moisturizer is formulated around Squalane and Hydroxypropyl Bispalmitamide Mea to strengthen the skin barrier and hydrate skin. This anti-aging moisturizer is formulated around Sclerocarya Birrea Seed Oil and Sh-Oligopeptide-1 to soften the look of wrinkles and hydrate skin. Water Butylene Glycol Glycerin Butylene Glycol Dicaprylate/Dicaprate Cetyl Ethylhexanoate Squalane Pentaerythrityl Tetraisostearate Dicaprylyl Carbonate Behenyl Alcohol Dimethicone Hydroxypropyl Bispalmitamide Mea Stearic Acid Betaine Mannitol C14-22 Alcohols Palmitic Acid Hydroxypropyl Bislauramide Mea Arachidyl Alcohol Cholesterol Polyacrylate-13 C12-20 Alkyl Glucoside Allantoin Arachidyl Glucoside Niacinamide Ceramide NP Glyceryl Caprylate Ethylhexylglycerin Hydrogenated Polyisobutene Carbomer Tromethamine Dimethiconol Polyglyceryl-10 Laurate Hydrogenated Lecithin Ethylhexyl Palmitate Acrylates/Ammonium Methacrylate Copolymer Sorbitan Isostearate Silica Phytosphingosine Sphingolipids Arachidic Acid Tocopherol Oleic Acid Water, Butylene Glycol, Glycerin, Butylene Glycol Dicaprylate/Dicaprate, Cetyl Ethylhexanoate, Squalane, Pentaerythrityl Tetraisostearate, Dicaprylyl Carbonate, Behenyl Alcohol, Dimethicone, Hydroxypropyl Bispalmitamide Mea, Stearic Acid, Betaine, Mannitol, C14-22 Alcohols, Palmitic Acid, Hydroxypropyl Bislauramide Mea, Arachidyl Alcohol, Cholesterol, Polyacrylate-13, C12-20 Alkyl Glucoside, Allantoin, Arachidyl Glucoside, Niacinamide, Ceramide NP, Glyceryl Caprylate, Ethylhexylglycerin, Hydrogenated Polyisobutene, Carbomer, Tromethamine, Dimethiconol, Polyglyceryl-10 Laurate, Hydrogenated Lecithin, Ethylhexyl Palmitate, Acrylates/Ammonium Methacrylate Copolymer, Sorbitan Isostearate, Silica, Phytosphingosine, Sphingolipids, Arachidic Acid, Tocopherol, Oleic Acid Cetearyl Alcohol Cetearyl Olivate Sorbitan Olivate Sclerocarya Birrea Seed Oil Bacillus/Folic Acid Ferment Filtrate Extract Nymphaea Alba Root Extract Sh-Oligopeptide-1 Sh-Oligopeptide-2 Sh-Polypeptide-1 Sh-Polypeptide-9 Sh-Polypeptide-11 Copper Palmitoyl Heptapeptide-14 Heptapeptide-15 Palmitate Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Alanine Arginine Glycine Histidine Isoleucine Phenylalanine Proline Serine Threonine Valine Acetyl Glutamine Coconut Alkanes Coco-Caprylate/Caprate Sodium Hyaluronate Aspartic Acid Linoleic Acid Linolenic Acid Lecithin Polyvinyl Alcohol Sodium Lactate Sodium PCA PCA Polysorbate 20 Polysorbate 60 Lactic Acid/Glycolic Acid Copolymer Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Xanthan Gum Isomalt 1,2-Hexanediol Caprylyl Glycol Chlorphenesin Phenoxyethanol Sodium Benzoate Phenylpropanol Symphytum Officinale Callus Culture Extract Water, Dicaprylyl Carbonate, Glycerin, Cetearyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Sclerocarya Birrea Seed Oil, Bacillus/Folic Acid Ferment Filtrate Extract, Nymphaea Alba Root Extract, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate/Caprate, Sodium Hyaluronate, Aspartic Acid, These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Dicaprylyl Carbonate comes from carbonic acid and caprylyl alcohol, a fatty alcohol. It is an emollient and gives skin a velvet feel. The sources of Dicaprylyl Carbonate may be synthetic or from animals. As an emollient, Dicaprylyl Carbonate creates a film on the skin. This film traps moisture in, keeping your skin soft and hydrated. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Glyceryl Caprylate comes from glycerin and caprylic acid. It is an emollient, co-emulsifier, and preservative booster. Its short C8 fatty acid chain makes it behave differently from its longer-chain emollient cousins like Glyceryl Stearate. It feels more lightweight, fast-absorbing, and silky instead of rich and waxy. As a co-emulsifier, its "head" and "tail" sit at the oil-water interface. But overall, the short C8 tail and not being water soluble means it doesn't really have the muscle to emulsify a formula on its own. T