Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

AHK-Cu vs GHK-Cu: Head-to-Head Comparison

This table consolidates the key differences across every relevant parameter. Amino acid sequence Gly-His-Lys-Cu2+ Ala-His-Lys-Cu2+ Molecular weight ~403 Da ~417 Da Natural (human plasma) Primary target Skin cells, fibroblasts, immune cells Dermal papilla cells

This source-based comparison does not add ratings or recommend a winner.

  • This table consolidates the key differences across every relevant parameter.
  • Amino acid sequence
  • Gly-His-Lys-Cu2+
  • Ala-His-Lys-Cu2+
  • Molecular weight
  • ~403 Da
  • ~417 Da
  • Natural (human plasma)
  • Primary target
  • Skin cells, fibroblasts, immune cells
  • Dermal papilla cells (hair follicles)
  • Genes modulated
  • 4,000+
  • Limited data
  • Collagen stimulation
  • Strong (types I and III)
  • Weak
  • Wound healing
  • Extensively documented
  • Not documented
  • Hair follicle elongation
  • Moderate
  • Strong (Pyo 2007)
  • DPC proliferation
  • Superior (Pyo 2007)
  • DHT reduction
  • Yes (copper ion mechanism)
  • Anti-inflammatory
  • Strong
  • ~15 years, limited studies
  • Skin anti-aging, wound healing, scars
  • Regulatory status
  • Research compound