Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Anua Nano Retinol 0.3% + Niacin Renewing Serum Versus COSRX The 6 Peptide Skin Booster Serum

Anua Nano Retinol 0.3% + Niacin Renewing Serum Versus COSRX The 6 Peptide Skin Booster Serum Detailed comparison of Anua Nano Retinol 0.3% + Niacin Renewing Serum versus COSRX The 6 Peptide Skin Booster Serum. This anti-aging serum is formulated around Niacina

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Anua Nano Retinol 0.3% + Niacin Renewing Serum Versus COSRX The 6 Peptide Skin Booster Serum Detailed comparison of Anua Nano Retinol 0.3% + Niacin Renewing Serum versus COSRX The 6 Peptide Skin Booster Serum. This anti-aging serum is formulated around Niacinamide and Retinol to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and strengthen the skin barrier. Water Glycereth-26 Niacinamide 5% Pyrus Malus Fruit Extract Glycerin 1,2-Hexanediol Caprylic/Capric Triglyceride Castanea Crenata Shell Extract Glyceryl Citrate/Lactate/Linoleate/Oleate Diospyros Kaki Leaf Extract Coptis Japonica Root Extract Potentilla Anserina Extract Avena Sativa Kernel Extract Cynara Scolymus Leaf Extract Portulaca Oleracea Extract Melaleuca Alternifolia Leaf Extract Ficus Carica Fruit Extract Centella Asiatica Extract Camellia Sinensis Leaf Extract Artemisia Capillaris Flower Extract Arnica Montana Flower Extract Houttuynia Cordata Extract Melia Azadirachta Leaf Extract Lavandula Angustifolia Flower Extract Chamomilla Recutita Flower/Leaf Extract Borago Officinalis Extract Centaurea Cyanus Flower Extract Hydrogenated Lecithin Camellia Sinensis Leaf Water Centaurea Cyanus Flower Water Sodium Hyaluronate Melaleuca Alternifolia Leaf Oil Carapa Guaianensis Seed Oil Hippophae Rhamnoides Acid Tocopherol Cetyl Ethylhexanoate Ammonium Acryloyldimethyltaurate/Vp Copolymer Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Polyacrylate Crosspolymer-6 Methylpropanediol Butylene Glycol Polysorbate 20 Retinol 0.1% Ceramide NP Pentylene Glycol Carbomer Tromethamine Dipotassium Glycyrrhizate Ethylhexylglycerin Adenosine Disodium EDTA Polyquaternium-51 Squalane Panthenol Hydrolyzed Sodium Hyaluronate BHT Oleic Acid Dipropylene Glycol BHA Allantoin Maltodextrin Saccharide Hydrolysate Sorbitan Laurate Glyceryl Stearate Butyrospermum Parkii Butter Octyldodecanol Phytosterols Madecassoside Ceramide As Ceramide AP Capryloyl Salicylic Acid Cholesterol Hydroxyethylcellulose Acetyl Dipeptide-1 Cetyl Ester Ceramide Ns Ceramide Ng Caprylyl Glycol Guaiazulene Sucrose Distearate Nonapeptide-1 Acetyl Hexapeptide-8 Copper Tripeptide-1 Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Palmitoyl Pentapeptide-4 Hydroxypropyl Cyclodextrin Hexapeptide-9 Ceramide EOP Water, Glycereth-26, Niacinamide 5%, Pyrus Malus Fruit Extract, Glycerin, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Castanea Crenata Shell Extract, Glyceryl Citrate/Lactate/Linoleate/Oleate, Diospyros Kaki Leaf Extract, Coptis Japonica Root Extract, Potentilla Anserina Extract, Avena Sativa Kernel Extract, Cynara Scolymus Leaf Extract, Portulaca Oleracea Extract, Melaleuca Alternifolia Leaf Extract, Ficus Carica Fruit Extract, Centella Asiatica Extract, Camellia Sinensis Leaf Extract, Artemisia Capillaris Flower Extract, Arnica Montana Flower Extract, Houttuynia Cordata Extract, Melia Azadirachta Leaf Extract, Lavandula Angustifolia Flower Extract, Chamomilla Recutita Flower/Leaf Extract, Borago Officinalis Extract, Centaurea Cyanus Flower Extract, Hydrogenated Lecithin, Camellia Sinensis Leaf Water, Centaurea Cyanus Flower Water, Sodium Hyaluronate, Melaleuca Alternifolia Leaf Oil, Carapa Guaianensis Seed Oil, Hippophae Rhamnoides Acid, Tocopherol, Cetyl Ethylhexanoate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Polyac These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it