Ingredient or product comparison
Best Research Peptides for Hair Loss: Evidence Comparison
GHK-Cu (Copper Peptide) Lysyl oxidase activation, collagen synthesis, copper chelation 340 Da Topical with penetration enhancers OR subcutaneous Level 2 (controlled human trials) 1–10 µM twice daily topical OR 2 mg subQ 2×/week 230% increase in dermal papilla
This source-based comparison does not add ratings or recommend a winner.
- GHK-Cu (Copper Peptide)
- Lysyl oxidase activation, collagen synthesis, copper chelation
- 340 Da
- Topical with penetration enhancers OR subcutaneous
- Level 2 (controlled human trials)
- 1–10 µM twice daily topical OR 2 mg subQ 2×/week
- 230% increase in dermal papilla cell proliferation; 12.3% increase in anagen follicles (meta-analysis)
- TB500 (Thymosin Beta-4 Fragment)
- VEGF upregulation, angiogenesis, actin polymerization
- 4963 Da
- Subcutaneous injection only
- Level 3 (preclinical + open-label human)
- 2 mg subQ 2×/week for 12 weeks
- 70% increase in perifollicular vessel density (mouse model); extended anagen phase duration
- PTD-DBM
- Wnt/β-catenin pathway activation, stem cell signaling
- ~5000 Da
- Intradermal injection
- Level 3 (Phase 2 trial, limited replication)
- 100 µg intradermal every 2 weeks for 16 weeks
- Anagen follicle percentage increased from 42% to 68% over 16 weeks (Seoul National University trial)