Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Biossance Squalane + Peptide Eye Gel Versus Murad Targeted Eye Depuffer

Biossance Squalane + Peptide Eye Gel Versus Murad Targeted Eye Depuffer Detailed comparison of Biossance Squalane + Peptide Eye Gel versus Murad Targeted Eye Depuffer. This anti-aging eye moisturizer is formulated around Squalane and Niacinamide to soften the

This source-based comparison does not add ratings or recommend a winner.

Biossance Squalane + Peptide Eye Gel Versus Murad Targeted Eye Depuffer Detailed comparison of Biossance Squalane + Peptide Eye Gel versus Murad Targeted Eye Depuffer. This anti-aging eye moisturizer is formulated around Squalane and Niacinamide to soften the look of wrinkles and hydrate skin. This anti-aging eye moisturizer is formulated around Caffeine and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and calm redness. Water Aloe Barbadensis Leaf Juice Squalane Niacinamide Glycerin Panthenol Chondrus Crispus Extract Malus Domestica Fruit Cell Culture Extract Acetyl Tetrapeptide-5 Acetyl Hexapeptide-8 Tocopherol Pentylene Glycol Cucumis Sativus Fruit Extract Tetrahexyldecyl Ascorbate Camellia Sinensis Leaf Extract Lycium Barbarum Fruit Extract Lycopene Vitis Vinifera Skin Extract Sodium Hyaluronate Caffeine Acacia Senegal Gum Dimethicone Crosspolymer Xanthan Gum Carbomer Ethyl Lauroyl Arginate Hcl Lecithin Ammonium Acryloyldimethyltaurate/Vp Copolymer Silica Phenoxyethanol Potassium Sorbate Citric Acid Caprylyl Glycol Water, Aloe Barbadensis Leaf Juice, Squalane, Niacinamide, Glycerin, Panthenol, Chondrus Crispus Extract, Malus Domestica Fruit Cell Culture Extract, Acetyl Tetrapeptide-5, Acetyl Hexapeptide-8, Tocopherol, Pentylene Glycol, Cucumis Sativus Fruit Extract, Tetrahexyldecyl Ascorbate, Camellia Sinensis Leaf Extract, Lycium Barbarum Fruit Extract, Lycopene, Vitis Vinifera Skin Extract, Sodium Hyaluronate, Caffeine, Acacia Senegal Gum, Dimethicone Crosspolymer, Xanthan Gum, Carbomer, Ethyl Lauroyl Arginate Hcl, Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Silica, Phenoxyethanol, Potassium Sorbate, Citric Acid, Caprylyl Glycol Isopentyldiol Propanediol Octyldodecanol Dimethyl Isosorbide Pyrus Malus Fruit Extract Pfaffia Paniculata Root Extract Ptychopetalum Olacoides Bark/Root Extract Lilium Candidum Flower Extract Acmella Oleracea Extract Tetrapeptide-1 Urea Yeast Amino Acids Trehalose Inositol Taurine Betaine Hydroxyacetophenone Ethylhexylglycerin Caprylyl/Capryl Glucoside Pvm/Ma Decadiene Crosspolymer Sodium Hydroxide Chlorphenesin Sodium Benzoate Benzyl Alcohol Xylitol Caprylic Acid Leuconostoc/Radish Root Ferment Filtrate Tin Oxide Synthetic Fluorphlogopite CI 77891 Water, Caffeine, Glycerin, Isopentyldiol, Propanediol, Octyldodecanol, Dimethyl Isosorbide, Pyrus Malus Fruit Extract, Pfaffia Paniculata Root Extract, Ptychopetalum Olacoides Bark/Root Extract, Lilium Candidum Flower Extract, Acmella Oleracea Extract, Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Tetrapeptide-1, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Hydroxyacetophenone, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Pvm/Ma Decadiene Crosspolymer, Silica, Sodium Hydroxide, Citric Acid, Chlorphenesin, Sodium Benzoate, Caprylyl Glycol, Benzyl Alcohol, Xylitol, Caprylic Acid, Leuconostoc/Radish Root Ferment Filtrate, Tocopherol, Tin Oxide, Synthetic Fluorphlogopite, CI 77891 These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana. As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors. Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp. You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited. Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness. Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes. Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath. However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products. Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH. In skincare formulas, citric acid can: While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants. Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations. Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger. However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure. Glycerin (or glycerol) is a compound naturally found in your