Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

BIOTHERM Blue Therapy Anti-Aging Night Cream Versus Paula's Choice Barrier Repair Advanced Moisturizer

BIOTHERM Blue Therapy Anti-Aging Night Cream Versus Paula's Choice Barrier Repair Advanced Moisturizer Detailed comparison of BIOTHERM Blue Therapy Anti-Aging Night Cream versus Paula's Choice Barrier Repair Advanced Moisturizer US. This anti-aging night moist

This source-based comparison does not add ratings or recommend a winner.

BIOTHERM Blue Therapy Anti-Aging Night Cream Versus Paula's Choice Barrier Repair Advanced Moisturizer Detailed comparison of BIOTHERM Blue Therapy Anti-Aging Night Cream versus Paula's Choice Barrier Repair Advanced Moisturizer US. This anti-aging night moisturizer is formulated around Adenosine and Vitreoscilla Ferment to soften the look of wrinkles. This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin. Water Hydrogenated Polyisobutene Glycerin Butylene Glycol Dimethicone Cetyl Alcohol Glyceryl Stearate Zea Mays Starch Elaeis Guineensis Oil Paraffinum Liquidum PEG-100 Stearate Cera Alba Sorbitol Myristyl Myristate Zea Mays Oil PEG-14m Cera Microcristallina Paraffin Algae Sorbitan Tristearate Glyceryl Acrylate/Acrylic Acid Copolymer Dimethyl Isosorbide Isohexadecane Laminaria Ochroleuca Extract Sodium Hydroxide Moringa Oleifera Seed Extract 2-Oleamido-1,3-Octadecanediol Phenoxyethanol Prunus Armeniaca Kernel Oil Adenosine Chlorphenesin Disodium EDTA Propylene Glycol Hydroxypropyl Tetrahydropyrantriol Capryloyl Salicylic Acid Vitreoscilla Ferment Passiflora Edulis Seed Oil Xanthan Gum Maltitol Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Octyldodecanol Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Polysorbate 80 Oryza Sativa Bran Oil Parfum Water, Hydrogenated Polyisobutene, Glycerin, Butylene Glycol, Dimethicone, Cetyl Alcohol, Glyceryl Stearate, Zea Mays Starch, Elaeis Guineensis Oil, Paraffinum Liquidum, PEG-100 Stearate, Cera Alba, Sorbitol, Myristyl Myristate, Zea Mays Oil, PEG-14m, Cera Microcristallina, Paraffin, Algae, Sorbitan Tristearate, Glyceryl Acrylate/Acrylic Acid Copolymer, Dimethyl Isosorbide, Isohexadecane, Laminaria Ochroleuca Extract, Sodium Hydroxide, Moringa Oleifera Seed Extract, 2-Oleamido-1,3-Octadecanediol, Phenoxyethanol, Prunus Armeniaca Kernel Oil, Adenosine, Chlorphenesin, Disodium EDTA, Propylene Glycol, Hydroxypropyl Tetrahydropyrantriol, Capryloyl Salicylic Acid, Vitreoscilla Ferment, Passiflora Edulis Seed Oil, Xanthan Gum, Maltitol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Octyldodecanol, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Polysorbate 80, Oryza Sativa Bran Oil, Parfum Dicaprylyl Carbonate Ethylhexyl Stearate Cocoglycerides Squalane Sodium Polyacrylate Butyrospermum Parkii Butter Ceramide NP Ceramide AP Ceramide As Ceramide Ns Ceramide EOP Sodium Hyaluronate Palmitoyl Tripeptide-5 Citrullus Lanatus Seed Oil Caprylyl Glycol Hydroxyacetophenone Sodium Stearoyl Glutamate Hexylene Glycol Tocopherol 2,3-Butanediol Ethylhexylglycerin Sodium Phytate Sodium PCA Urea Hydrogenated Lecithin Trehalose Polyquaternium-51 Triacetin Cholesterol Water, Dicaprylyl Carbonate, Ethylhexyl Stearate, Glycerin, Cocoglycerides, Squalane, Sodium Polyacrylate, Butyrospermum Parkii Butter, Ceramide NP, Ceramide AP, Ceramide As, Ceramide Ns, Ceramide EOP, Sodium Hyaluronate, Adenosine, Palmitoyl Tripeptide-5, Citrullus Lanatus Seed Oil, Glyceryl Stearate, Caprylyl Glycol, Hydroxyacetophenone, Sodium Stearoyl Glutamate, Hexylene Glycol, Tocopherol, 2,3-Butanediol, Xanthan Gum, Ethylhexylglycerin, Sodium Phytate, Sodium PCA, Urea, Hydrogenated Lecithin, Trehalose, Polyquaternium-51, Triacetin, Cholesterol, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive. Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture. This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic. A close cousin of this ingredient is Glyceryl Stearate