Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Bottega Verde Retinolo BV Plus Siero Versus Perricone MD High Potency Growth Factor Firming & Lifting Serum

Bottega Verde Retinolo BV Plus Siero Versus Perricone MD High Potency Growth Factor Firming & Lifting Serum Detailed comparison of Bottega Verde Retinolo BV Plus Siero versus Perricone MD High Potency Growth Factor Firming & Lifting Serum. This anti-aging seru

This source-based comparison does not add ratings or recommend a winner.

Bottega Verde Retinolo BV Plus Siero Versus Perricone MD High Potency Growth Factor Firming & Lifting Serum Detailed comparison of Bottega Verde Retinolo BV Plus Siero versus Perricone MD High Potency Growth Factor Firming & Lifting Serum. This anti-aging serum is formulated around Panax Ginseng Root Extract and Retinyl Palmitate to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Niacinamide and Retinol to soften the look of wrinkles and refine skin texture. Water Octyldodecanol Hydrogenated Ethylhexyl Olivate Pentylene Glycol Glyceryl Oleate Citrate Polymethyl Methacrylate Hydrogenated Olive Oil Unsaponifiables Hydroxyacetophenone Tricaprylin Caprylic/Capric Triglyceride Panax Ginseng Root Extract Silybum Marianum Fruit Extract Triticum Vulgare Germ Extract Glycine Soja Germ Extract Retinyl Palmitate Retinol Caprylyl Glycol Xanthan Gum Acacia Senegal Gum 1,2-Hexanediol Acrylates/C10-30 Alkyl Acrylate Crosspolymer Trisodium Ethylenediamine Disuccinate Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate BHT Alcohol Denat. Dilauryl Thiodipropionate Phenoxyethanol Sodium Hydroxide Ethylhexylglycerin Butylene Glycol PEG-60 Hydrogenated Castor Oil Citric Acid Glucose Carrageenan Tocopheryl Acetate Ascorbyl Palmitate Sodium Benzoate Potassium Sorbate Tocopherol Water, Octyldodecanol, Hydrogenated Ethylhexyl Olivate, Pentylene Glycol, Glyceryl Oleate Citrate, Polymethyl Methacrylate, Hydrogenated Olive Oil Unsaponifiables, Hydroxyacetophenone, Tricaprylin, Caprylic/Capric Triglyceride, Panax Ginseng Root Extract, Silybum Marianum Fruit Extract, Triticum Vulgare Germ Extract, Glycine Soja Germ Extract, Retinyl Palmitate, Retinol, Caprylyl Glycol, Xanthan Gum, Acacia Senegal Gum, 1,2-Hexanediol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Trisodium Ethylenediamine Disuccinate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, BHT, Alcohol Denat., Dilauryl Thiodipropionate, Phenoxyethanol, Sodium Hydroxide, Ethylhexylglycerin, Butylene Glycol, PEG-60 Hydrogenated Castor Oil, Citric Acid, Glucose, Carrageenan, Tocopheryl Acetate, Ascorbyl Palmitate, Sodium Benzoate, Potassium Sorbate, Tocopherol Heptyl Undecylenate Lecithin Niacinamide Pentaerythrityl Adipate/Caprate/Caprylate/Heptanoate Phosphatidylcholine Hydrolyzed Egg Shell Membrane Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Dipropylene Glycol Cetearyl Alcohol Stearic Acid Glyceryl Stearate PEG-100 Stearate Spermidine Sodium Polyacrylate Parfum Limonene Linalool Hydroxycitronellal Citronellol Benzyl Alcohol Geraniol Water, Butylene Glycol, Heptyl Undecylenate, Lecithin, Alcohol Denat., Polymethyl Methacrylate, Niacinamide, Pentaerythrityl Adipate/Caprate/Caprylate/Heptanoate, Phosphatidylcholine, Ascorbyl Palmitate, Hydrolyzed Egg Shell Membrane, Tricaprylin, Retinol, Tocopherol, BHT, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dipropylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Alcohol, Stearic Acid, Caprylyl Glycol, Glyceryl Stearate, PEG-100 Stearate, Spermidine, Sodium Polyacrylate, Phenoxyethanol, Parfum, Limonene, Linalool, Hydroxycitronellal, Citronellol, Benzyl Alcohol, Geraniol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives. The "denat" part just means "denatured"; common denaturants include Denatonium Benzoate, t-butyl alcohol, and Diethyl Phthalate. This step makes the alcohol undrinkable (and lets brand skip taxes related to beverage alcohol). This ingredient gets a bad rep because it is irritating and drying due to its astringent property. Astringents draw out natural oils in tissue to constrict pores and dry out your skin. However, alcohol denat. is not all that bad. Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin. This also helps other ingredients become better absorbed upon application. Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged. Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments. The rule of thumb is this ingredient will probably not affect your skin much if it is near the end of an ingredients list. One thing to note: People with ALDH2 (aldehyde dehydrogenase 2) deficiency may experience skin irritation from continued alcohol use. About 8% of the world's population have this deficiency. The Cosmetic Ingredient Review Expert Panel has determined denatured alcohols to be safe for use in concentrations between 0.05% and 12% (depending on which denaturant is used). Also... This ingredient has antimicrobial and solvent properties. The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients. Look for formulas that contain glycerin, hyaluronic acid, or panthenol if you want to offset any drying effect. This ingredient will trip away your skin's natural oils/lipids that help it lock in moisture. This can worsen dryness, trigger eczema flare-ups, and aggravate rosacea. Be sure to patch test any product with this ingredient if you have dry or sensitive skin, eczema, or rosacea. Ascorbyl P