Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

CeraVe Itch Relief Moisturizing Lotion Versus Paula's Choice Water-Infusing Electrolyte Moisturizer

CeraVe Itch Relief Moisturizing Lotion Versus Paula's Choice Water-Infusing Electrolyte Moisturizer Detailed comparison of CeraVe Itch Relief Moisturizing Lotion versus Paula's Choice Water-Infusing Electrolyte Moisturizer EU. This calming moisturizer is formu

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CeraVe Itch Relief Moisturizing Lotion Versus Paula's Choice Water-Infusing Electrolyte Moisturizer Detailed comparison of CeraVe Itch Relief Moisturizing Lotion versus Paula's Choice Water-Infusing Electrolyte Moisturizer EU. This calming moisturizer is formulated around Niacinamide and Ceramide NP to calm redness and strengthen the skin barrier. This moisturizer is formulated around Potassium PCA and Magnesium PCA to hydrate skin. Pramoxine Hydrochloride 1% Water Isopropyl Myristate PEG-100 Stearate Glyceryl Stearate Cetearyl Alcohol Cetyl Alcohol Glycerin Niacinamide Dimethicone Stearic Acid Allantoin Potassium Phosphate Ceramide NP Ceramide AP Ceramide EOP Carbomer Zinc Citrate Behentrimonium Methosulfate Sodium Hydroxide Sodium Lauroyl Lactylate Arginine PCA Myristic Acid Sodium PCA Cholesterol Palmitic Acid Tasmannia Lanceolata Fruit Extract Phenoxyethanol Dipotassium Phosphate Disodium EDTA Alcohol Denat. Tocopheryl Acetate Hydrolyzed Hyaluronic Acid Xanthan Gum Phytosphingosine Polyglyceryl-3 Diisostearate Ethylhexylglycerin Pramoxine Hydrochloride 1%, Water, Isopropyl Myristate, PEG-100 Stearate, Glyceryl Stearate, Cetearyl Alcohol, Cetyl Alcohol, Glycerin, Niacinamide, Dimethicone, Stearic Acid, Allantoin, Potassium Phosphate, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Zinc Citrate, Behentrimonium Methosulfate, Sodium Hydroxide, Sodium Lauroyl Lactylate, Arginine PCA, Myristic Acid, Sodium PCA, Cholesterol, Palmitic Acid, Tasmannia Lanceolata Fruit Extract, Phenoxyethanol, Dipotassium Phosphate, Disodium EDTA, Alcohol Denat., Tocopheryl Acetate, Hydrolyzed Hyaluronic Acid, Xanthan Gum, Phytosphingosine, Polyglyceryl-3 Diisostearate, Ethylhexylglycerin Butylene Glycol Propanediol Isohexadecane Potassium PCA Magnesium PCA Calcium PCA Ethylhexyl Olivate Polyglyceryl-4 Olivate Pyrus Malus Fruit Extract Laminaria Saccharina Extract Actinidia Chinensis Fruit Extract Coffea Arabica Seed Extract Biotin/Folic Acid/Cyanocobalamin/Niacinamide/Pantothenic Acid/Pyridoxine/Riboflavin/Thiamine/Yeast Polypeptides Garcinia Mangostana Peel Extract Prunus Serotina Fruit Extract Squalane Pisum Sativum Extract Acetyl Hexapeptide-37 Oryza Sativa Bran Extract Tocopherol Creatine Bisabolol Sorbitol Inositol Xylitol Caprylic/Capric Triglyceride Sodium Levulinate Behenyl Behenate Tribehenin Sodium Acrylates Copolymer Acrylates/C10-30 Alkyl Acrylate Crosspolymer Tetrasodium EDTA Water, Glycerin, Dimethicone, Butylene Glycol, Propanediol, Stearic Acid, Glyceryl Stearate, Isohexadecane, Potassium PCA, Magnesium PCA, Calcium PCA, Ethylhexyl Olivate, Polyglyceryl-4 Olivate, Pyrus Malus Fruit Extract, Laminaria Saccharina Extract, Actinidia Chinensis Fruit Extract, Coffea Arabica Seed Extract, Biotin/Folic Acid/Cyanocobalamin/Niacinamide/Pantothenic Acid/Pyridoxine/Riboflavin/Thiamine/Yeast Polypeptides, Garcinia Mangostana Peel Extract, Prunus Serotina Fruit Extract, Squalane, Ceramide EOP, Ceramide AP, Ceramide NP, Pisum Sativum Extract, Phytosphingosine, Cholesterol, Acetyl Hexapeptide-37, Oryza Sativa Bran Extract, Tocopherol, Creatine, Bisabolol, Sorbitol, Inositol, Xylitol, Caprylic/Capric Triglyceride, Sodium Levulinate, Behenyl Behenate, Tribehenin, Sodium Lauroyl Lactylate, Xanthan Gum, Sodium Acrylates Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Sodium Hydroxide, Tetrasodium EDTA, Phenoxyethanol, Ethylhexylglycerin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function. You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has. The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function. Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration. Ceramide EOP is formally known as Ceramide 1. It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer. EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base. What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do). Low levels of Ceramide EOP have been found in people with eczema and psoriasis. Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss. In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks. You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum co