Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Clinique Clarifying Lotion 3 Versus Paula's Choice Resist Advanced Replenishing Toner

Clinique Clarifying Lotion 3 Versus Paula's Choice Resist Advanced Replenishing Toner Detailed comparison of Clinique Clarifying Lotion 3 versus Paula's Choice Resist Advanced Replenishing Toner. This oil-control exfoliator is formulated around Salicylic Acid

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Clinique Clarifying Lotion 3 Versus Paula's Choice Resist Advanced Replenishing Toner Detailed comparison of Clinique Clarifying Lotion 3 versus Paula's Choice Resist Advanced Replenishing Toner. This oil-control exfoliator is formulated around Salicylic Acid to balance excess oil and refine skin texture. This barrier-repair toner is formulated around Linoleic Acid and Phospholipids to strengthen the skin barrier and hydrate skin. Water Alcohol Denat. Salicylic Acid Hamamelis Virginiana Water Butylene Glycol Glycerin Trehalose Sodium Hyaluronate Citric Acid Sodium Hydroxide Disodium EDTA BHT Phenoxyethanol Benzophenone-4 Extracts CI 60730 CI 15850 CI 15510 Water, Alcohol Denat., Salicylic Acid, Hamamelis Virginiana Water, Butylene Glycol, Glycerin, Trehalose, Sodium Hyaluronate, Citric Acid, Sodium Hydroxide, Disodium EDTA, BHT, Phenoxyethanol, Benzophenone-4, Extracts, CI 60730, CI 15850, CI 15510 Cyclopentasiloxane Glycereth-26 Polysorbate 20 Dimethiconol Linoleic Acid Oleic Acid Linolenic Acid Phospholipids Carnosine Epigallocatechin Gallate Genistein Sphingolipids Ferulic Acid Laurdimonium Hydroxypropyl Hydrolyzed Soy Protein Glycyrrhiza Glabra Root Extract Acetyl Glucosamine Quercetin Oenothera Biennis Oil Beta Vulgaris Root Extract Cucurbita Pepo Seed Extract Lecithin Caprylic/Capric Triglyceride Hydrolyzed Corn Starch Hydrogenated Lecithin Palmitic Acid Acrylates/C10-30 Alkyl Acrylate Crosspolymer Xanthan Gum Laureth-23 Laureth-4 Aminomethyl Propanol Sodium Benzoate Ethylhexylglycerin Chlorphenesin Benzoic Acid Sorbic Acid Water, Cyclopentasiloxane, Glycerin, Glycereth-26, Polysorbate 20, Dimethiconol, Linoleic Acid, Oleic Acid, Linolenic Acid, Phospholipids, Carnosine, Epigallocatechin Gallate, Genistein, Sodium Hyaluronate, Sphingolipids, Ferulic Acid, Laurdimonium Hydroxypropyl Hydrolyzed Soy Protein, Glycyrrhiza Glabra Root Extract, Acetyl Glucosamine, Quercetin, Oenothera Biennis Oil, Beta Vulgaris Root Extract, Cucurbita Pepo Seed Extract, Lecithin, Caprylic/Capric Triglyceride, Hydrolyzed Corn Starch, Hydrogenated Lecithin, Palmitic Acid, Butylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Laureth-23, Laureth-4, Aminomethyl Propanol, Disodium EDTA, Sodium Benzoate, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin, Benzoic Acid, Sorbic Acid These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effective