Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Clinique Dramatically Different Hydrating Jelly Versus First Aid Beauty Ultra Repair Hydra-Firm Night Cream

Clinique Dramatically Different Hydrating Jelly Versus First Aid Beauty Ultra Repair Hydra-Firm Night Cream Detailed comparison of Clinique Dramatically Different Hydrating Jelly US versus First Aid Beauty Ultra Repair Hydra-Firm Night Cream. This barrier-repa

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Clinique Dramatically Different Hydrating Jelly Versus First Aid Beauty Ultra Repair Hydra-Firm Night Cream Detailed comparison of Clinique Dramatically Different Hydrating Jelly US versus First Aid Beauty Ultra Repair Hydra-Firm Night Cream. This barrier-repair moisturizer is formulated around Cucumis Sativus Fruit Extract and Sodium Hyaluronate to strengthen the skin barrier and hydrate skin. This anti-aging night moisturizer is formulated around Butyrospermum Parkii Butter and Niacinamide to soften the look of wrinkles and hydrate skin. Water Bis-PEG-18 Methyl Ether Dimethyl Silane Butylene Glycol Glycerin Cucumis Sativus Fruit Extract Hypnea Musciformis Extract Gelidiella Acerosa Extract Hordeum Vulgare Extract Padina Pavonica Thallus Extract Helianthus Annuus Seedcake Sucrose Caffeine Sodium Hyaluronate Hydroxyethyl Urea Hydrolyzed Rice Extract Sorbitol Sodium Polyaspartate PPG-6-Decyltetradeceth-30 Ethylhexylglycerin Propylene Glycol Dicaprate Caprylyl Glycol Trehalose Polysorbate 80 Carbomer Sodium Hydroxide Hexylene Glycol Citric Acid Sodium Citrate Disodium EDTA Phenoxyethanol Water, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Glycerin, Cucumis Sativus Fruit Extract, Hypnea Musciformis Extract, Gelidiella Acerosa Extract, Hordeum Vulgare Extract, Padina Pavonica Thallus Extract, Helianthus Annuus Seedcake, Sucrose, Caffeine, Sodium Hyaluronate, Hydroxyethyl Urea, Hydrolyzed Rice Extract, Sorbitol, Sodium Polyaspartate, PPG-6-Decyltetradeceth-30, Ethylhexylglycerin, Propylene Glycol Dicaprate, Caprylyl Glycol, Trehalose, Polysorbate 80, Carbomer, Sodium Hydroxide, Hexylene Glycol, Citric Acid, Sodium Citrate, Disodium EDTA, Phenoxyethanol Caprylic/Capric Triglyceride Butyrospermum Parkii Butter Dimethicone Glyceryl Stearate C10-18 Triglycerides Ethylhexyl Palmitate Lactobacillus Ferment Jojoba Esters Cetyl Alcohol Niacinamide Spilanthes Acmella Flower Extract Helianthus Annuus Seed Cera Acacia Decurrens Flower Cera Algae Extract Palmitoyl Tripeptide-38 Avena Sativa Kernel Flour Palmitoyl Hexapeptide-12 Palmitoyl Tetrapeptide-7 Camellia Sinensis Leaf Extract Chrysanthemum Parthenium Extract Glycyrrhiza Glabra Root Extract Hydroxypropyl Cyclodextrin Sodium Lactate PEG-75 Stearate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Ceteth-20 Steareth-20 Polyglycerin-3 Polysorbate 20 Xanthan Gum Tetrasodium EDTA Water, Glycerin, Caprylic/Capric Triglyceride, Butyrospermum Parkii Butter, Dimethicone, Glyceryl Stearate, C10-18 Triglycerides, Ethylhexyl Palmitate, Lactobacillus Ferment, Jojoba Esters, Cetyl Alcohol, Niacinamide, Spilanthes Acmella Flower Extract, Helianthus Annuus Seed Cera, Acacia Decurrens Flower Cera, Algae Extract, Palmitoyl Tripeptide-38, Sodium Hyaluronate, Avena Sativa Kernel Flour, Palmitoyl Hexapeptide-12, Palmitoyl Tetrapeptide-7, Camellia Sinensis Leaf Extract, Chrysanthemum Parthenium Extract, Glycyrrhiza Glabra Root Extract, Hydroxypropyl Cyclodextrin, Sodium Lactate, Butylene Glycol, PEG-75 Stearate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ceteth-20, Steareth-20, Polyglycerin-3, Carbomer, Polysorbate 20, Phenoxyethanol, Xanthan Gum, Tetrasodium EDTA, Sodium Hydroxide These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the f