Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Clinique Repairwear Laser Focus Smooths, Restores, Corrects Face Serum Versus Neogold Peptide 6X Wrinkle Erase Serum

Clinique Repairwear Laser Focus Smooths, Restores, Corrects Face Serum Versus Neogold Peptide 6X Wrinkle Erase Serum Detailed comparison of Clinique Repairwear Laser Focus Smooths, Restores, Corrects Face Serum versus Neogold Peptide 6X Wrinkle Erase Serum. Th

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Clinique Repairwear Laser Focus Smooths, Restores, Corrects Face Serum Versus Neogold Peptide 6X Wrinkle Erase Serum Detailed comparison of Clinique Repairwear Laser Focus Smooths, Restores, Corrects Face Serum versus Neogold Peptide 6X Wrinkle Erase Serum. This anti-aging serum is formulated around Acetyl Glucosamine and Acetyl Hexapeptide-8 to soften the look of wrinkles. This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture. Water Dimethicone Butylene Glycol Methyl Trimethicone Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer Polysorbate 20 Bis-PEG-18 Methyl Ether Dimethyl Silane Glycerin Silica Polymethylsilsesquioxane Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone Methyl Gluceth-20 Polysilicone-11 Sigesbeckia Orientalis Extract Salvia Sclarea Extract Acetyl Glucosamine Plankton Extract Whey Protein Sea Whip Extract Arabidopsis Thaliana Extract Caffeine Acetyl Hexapeptide-8 Glycine Soja Protein Sodium Hyaluronate Micrococcus Lysate Palmitoyl Oligopeptide Ergothioneine Aminopropyl Ascorbyl Phosphate Caprylyl Glycol Ethylhexylglycerin Tocopheryl Acetate Cholesterol Glyceryl Polymethacrylate Sodium Hydroxide Lecithin Carbomer PEG-8 Xanthan Gum Citric Acid Disodium EDTA Phenoxyethanol Water, Dimethicone, Butylene Glycol, Methyl Trimethicone, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Polysorbate 20, Bis-PEG-18 Methyl Ether Dimethyl Silane, Glycerin, Silica, Polymethylsilsesquioxane, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Methyl Gluceth-20, Polysilicone-11, Sigesbeckia Orientalis Extract, Salvia Sclarea Extract, Acetyl Glucosamine, Plankton Extract, Whey Protein, Sea Whip Extract, Arabidopsis Thaliana Extract, Caffeine, Acetyl Hexapeptide-8, Glycine Soja Protein, Sodium Hyaluronate, Micrococcus Lysate, Palmitoyl Oligopeptide, Ergothioneine, Aminopropyl Ascorbyl Phosphate, Caprylyl Glycol, Ethylhexylglycerin, Tocopheryl Acetate, Cholesterol, Glyceryl Polymethacrylate, Sodium Hydroxide, Lecithin, Carbomer, PEG-8, Xanthan Gum, Citric Acid, Disodium EDTA, Phenoxyethanol Pyrus Malus Fiber PEG-12 Dimethicone Aloe Barbadensis Leaf Juice Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Pentapeptide-18 Palmitoyl Tripeptide-37 Chenopodium Quinoa Seed Extract Rosa Damascena Flower Extract Soluble Collagen Centella Asiatica Extract Camellia Sinensis Leaf Extract Punica Granatum Extract Rubus Fruticosus Fruit Extract Coffea Robusta Seed Extract Vaccinium Macrocarpon Fruit Extract Vitis Vinifera Leaf Extract Euterpe Oleracea Fruit Extract Arctostaphylos Uva-Ursi Leaf Extract Lycium Barbarum Fruit Extract Morinda Citrifolia Fruit Extract Rubus Idaeus Fruit Aristotelia Chilensis Fruit Extract Tetrasodium Glutamate Diacetate Brassica Oleracea Acephala Leaf Extract Parfum Hexylene Glycol Water, Glycerin, Pyrus Malus Fiber, PEG-12 Dimethicone, Aloe Barbadensis Leaf Juice, Sodium Hyaluronate, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Pentapeptide-18, Palmitoyl Tripeptide-37, Chenopodium Quinoa Seed Extract, Rosa Damascena Flower Extract, Soluble Collagen, Butylene Glycol, Carbomer, Centella Asiatica Extract, Camellia Sinensis Leaf Extract, Punica Granatum Extract, Rubus Fruticosus Fruit Extract, Coffea Robusta Seed Extract, Vaccinium Macrocarpon Fruit Extract, Vitis Vinifera Leaf Extract, Euterpe Oleracea Fruit Extract, Arctostaphylos Uva-Ursi Leaf Extract, Lycium Barbarum Fruit Extract, Morinda Citrifolia Fruit Extract, Rubus I These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes. Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin