Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Clinique Smart Clinical Repair Lifting Face + Neck Cream Versus Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream

Clinique Smart Clinical Repair Lifting Face + Neck Cream Versus Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream Detailed comparison of Clinique Smart Clinical Repair Lifting Face + Neck Cream versus Peter Thomas Roth Peptide Skinjection Moisture

This source-based comparison does not add ratings or recommend a winner.

Clinique Smart Clinical Repair Lifting Face + Neck Cream Versus Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream Detailed comparison of Clinique Smart Clinical Repair Lifting Face + Neck Cream versus Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream. This anti-aging moisturizer is formulated around Butyrospermum Parkii Butter and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin. This anti-aging moisturizer is formulated around Squalane and Hexapeptide-11 to soften the look of wrinkles and hydrate skin. Water Butyrospermum Parkii Butter Butylene Glycol Caprylic/Capric/Myristic/Stearic Triglyceride Polyglyceryl-3 Methylglucose Distearate Glycerin Coco-Caprylate/Caprate Simmondsia Chinensis Seed Oil Polyglyceryl-10 Pentastearate Glyceryl Stearate Behenyl Alcohol Ricinus Communis Seed Oil Mangifera Indica Seed Butter Prunus Amygdalus Dulcis Seed Extract Caffeine Dimethicone Ethylhexylglycerin Dimethicone/Vinyl Dimethicone Crosspolymer Caprylyl Glycol Cera Alba Sodium Hyaluronate Acetyl Hexapeptide-8 Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 PEG-8 PEG-100 Stearate Glyceryl Polymethacrylate Acrylates/Va Copolymer Copernicia Cerifera Cera Potassium Cetyl Phosphate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Sodium Stearoyl Lactylate Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Stearic Acid Hexylene Glycol Sodium Hydroxide Carbomer Polysorbate 60 Sorbitan Isostearate Polysorbate 20 Tocopheryl Acetate Tocopherol Disodium EDTA Phenoxyethanol Chlorphenesin Potassium Sorbate Mica CI 77891 Water, Butyrospermum Parkii Butter, Butylene Glycol, Caprylic/Capric/Myristic/Stearic Triglyceride, Polyglyceryl-3 Methylglucose Distearate, Glycerin, Coco-Caprylate/Caprate, Simmondsia Chinensis Seed Oil, Polyglyceryl-10 Pentastearate, Glyceryl Stearate, Behenyl Alcohol, Ricinus Communis Seed Oil, Mangifera Indica Seed Butter, Prunus Amygdalus Dulcis Seed Extract, Caffeine, Dimethicone, Ethylhexylglycerin, Dimethicone/Vinyl Dimethicone Crosspolymer, Caprylyl Glycol, Cera Alba, Sodium Hyaluronate, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, PEG-8, PEG-100 Stearate, Glyceryl Polymethacrylate, Acrylates/Va Copolymer, Copernicia Cerifera Cera, Potassium Cetyl Phosphate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Stearoyl Lactylate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Stearic Acid, Hexylene Glycol, Sodium Hydroxide, Carbomer, Polysorbate 60, Sorbitan Isostearate, Polysorbate 20, Tocopheryl Acetate, Tocopherol, Disodium EDTA, Phenoxyethanol, Chlorphenesin, Potassium Sorbate, Mica, CI 77891 Olive Oil Decyl Esters Glycereth-26 Squalane Polysilicone-11 Batyl Alcohol Hexapeptide-11 Dipeptide Diaminobutyroyl Benzylamide Diacetate Palmitoyl Tripeptide-5 Tripeptide-10 Citrulline Acetyl Hexapeptide-1 Acetyl Tetrapeptide-11 Acetyl Tetrapeptide-9 Acetyl Tetrapeptide-2 Acetyl Octapeptide-3 Palmitoyl Hexapeptide-19 Trifluoroacetyl Tripeptide-2 Tripeptide-1 Palmitoyl Oligopeptide Natto Gum Sodium Polyglutamate Squalene Sorbic Acid Cereus Grandiflorus Flower Extract Pseudoalteromonas Ferment Extract Leuconostoc/Radish Root Ferment Filtrate Magnesium Chloride Cetyl Alcohol Stearyl Alcohol Trehalose Silanetriol Trehalose Ether Mannitol Phytosterols Caprylic/Capric Triglyceride Hydrogenated Lecithin Polyglyceryl-10 Myristate Dimethyl Isosorbide Sodium Benzoate Laureth-12 Hydrolyzed Wheat Protein Lecithin Disodium Phosphate Hydrolyzed Soy Protein Dextra These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Behenyl Alcohol is a type of fatty alcohol (these are different from the drying, solvent alcohols). Fatty Alcohols have hydrating properties and are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils; behenyl alcohol is derived from the fats of vegetable oils. Emollients help keep your skin soft and hydrated by creating a film that traps moisture in. In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it i